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TARS2 Antibody, HRP conjugated

  • 中文名稱:
    TARS2兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào):
    CSB-PA023132LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TARS2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    TARS2 antibody; TARSL1 antibody; Threonine--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.3 antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody; Threonyl-tRNA synthetase-like 1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
  • 基因功能參考文獻(xiàn):
    1. Identification of a TARS2 splicing variant in several human cell lines, which encodes a hmtThrRS derivative lacking a peptide covering a portion of both the editing and the aminoacylation domains. PMID: 26811336
    2. TARS2 mutations caused fatal mitochondrial encephalomyopathy in two siblings. PMID: 24827421
  • 相關(guān)疾病:
    Combined oxidative phosphorylation deficiency 21 (COXPD21)
  • 亞細(xì)胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Class-II aminoacyl-tRNA synthetase family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 30740

    OMIM: 612805

    KEGG: hsa:80222

    STRING: 9606.ENSP00000358060

    UniGene: Hs.288974



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