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  4. TARS2 Antibody, Biotin conjugated

TARS2 Antibody, Biotin conjugated

  • 中文名稱：
    TARS2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA023132LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TARS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    TARS2 antibody; TARSL1 antibody; Threonine--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.3 antibody; Threonyl-tRNA synthetase antibody; ThrRS antibody; Threonyl-tRNA synthetase-like 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Threonine--tRNA ligase, mitochondrial protein (369-718AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
  • 基因功能參考文獻：
    1. Identification of a TARS2 splicing variant in several human cell lines, which encodes a hmtThrRS derivative lacking a peptide covering a portion of both the editing and the aminoacylation domains. PMID: 26811336
    2. TARS2 mutations caused fatal mitochondrial encephalomyopathy in two siblings. PMID: 24827421
  • 相關疾病：
    Combined oxidative phosphorylation deficiency 21 (COXPD21)
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-II aminoacyl-tRNA synthetase family
  • 數據庫鏈接：

    HGNC: 30740

    OMIM: 612805

    KEGG: hsa:80222

    STRING: 9606.ENSP00000358060

    UniGene: Hs.288974



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