在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TAPBPL Antibody, FITC conjugated

  • 中文名稱:
    TAPBPL兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA887144LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TAPBPL Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TAPBPL
  • 別名:
    FLJ10143 antibody; TAP binding protein like antibody; TAP binding protein related antibody; TAP binding protein related protein antibody; TAP-binding protein-like antibody; TAP-binding protein-related protein antibody; Tapasin like antibody; Tapasin R antibody; Tapasin Related Protein antibody; Tapasin-like antibody; TAPASIN-R antibody; Tapasin-related protein antibody; TAPBP L antibody; TAPBP R antibody; TAPBP-R antibody; Tapbpl antibody; TAPBPR antibody; TPSNR_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tapasin-related protein (201-468AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC).
  • 基因功能參考文獻:
    1. soluble TAPBPR, consisting of the luminal domain alone, added to intact cells, also functions as an effective peptide editor on surface MHC I molecules. PMID: 30213851
    2. this study reports the crystal structure of MHC I in complex with the peptide editor TAPBPR (TAP-binding protein-related), a tapasin homolog. PMID: 29025991
    3. this study presents the x-ray structure of the TAPBPR-MHC I complex, which delineates the central step of catalysis. PMID: 29025996
    4. The authors identify an interaction between TAPBPR and UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1), a folding sensor in the calnexin/calreticulin quality control cycle that is known to regenerate the Glc1Man9GlcNAc2 moiety on glycoproteins. The results suggest the formation of a multimeric complex, dependent on a conserved cysteine at position 94 in TAPBPR, in which TAPBPR promotes the association of UGT1 with p PMID: 28425917
    5. It is now clear there are two MHC class I specific peptide editors, tapasin and TAPBPR, intimately involved in controlling peptide presentation to the immune system. PMID: 26439010
    6. These results support a role of TAPBPR in stabilizing peptide-receptive conformation(s) of MHC-I, permitting peptide editing. PMID: 26869717
    7. TAPBPR is a new player in the MHC class I presentation pathway. (Review) PMID: 25720504
    8. The longer TAPBPR protein interacted with MHC class I but was attenuated in its ability to down-regulate surface expression of MHC class I. PMID: 24444341
    9. the data indicate that TAPBPR and tapasin bind in a similar orientation to the same face of MHC class I. PMID: 24163410
    10. The function of the tapasin-related protein, TAPBPR, was investigated. PMID: 23401559

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Mainly found in endoplasmic reticulum but a minority is found on the cell surface (PubMed:11920573).
  • 數據庫鏈接:

    HGNC: 30683

    OMIM: 607081

    KEGG: hsa:55080

    STRING: 9606.ENSP00000266556

    UniGene: Hs.504597



主站蜘蛛池模板: 99久久亚洲精品日本无码| 女人被躁到高潮免费视频软件| 99久热国产精品视频尤物| 国产日韩av免费无码一区二区三区| 色婷婷av久久久久久久| 亚洲第一极品精品无码| 色777狠狠狠综合| 亚洲日韩av无码| 久久精品黄aa片一区二区三区| 亚洲和欧洲一码二码区别7777 | 国产精品亚洲综合色区| 国产精品午夜小视频观看| 在线观看午夜亚洲一区| 巨大黑人极品videos精品| 久久综合一色综合久久小蛇| 国产成人片无码免费视频软件| 亚洲国产欧美在线人成| 色丁香婷婷综合久久| 老司机导航亚洲精品导航| 国产男生夜间福利免费网站| 亚洲午夜福利在线视频| 日韩人妻无码一区二区三区| 青春草在线视频免费观看| 亚洲日韩穿丝袜在线推荐| 在线 v亚洲 v欧美v 专区| 国产成人亚洲精品无码h在线| 国产精品无码a∨精品影院app| 久久―日本道色综合久久 | 国产精品久久福利网站| 日韩在线视频线观看一区| 婷婷成人五月综合激情| 中文字幕无码乱人伦| 免费人成视频在线观看视频| 国产成人a∨麻豆精品| 欧美性色黄大片| 欧美破苞系列二十三| 久久永久免费专区人妻精品| 成人午夜福利视频后入| 久久人人爽人人爽人人片av麻烦| 免费看女人与善牲交| 免费看又色又爽又黄的国产软件|