在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TAPBPL Antibody, Biotin conjugated

  • 中文名稱:
    TAPBPL兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA887144LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TAPBPL Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TAPBPL
  • 別名:
    FLJ10143 antibody; TAP binding protein like antibody; TAP binding protein related antibody; TAP binding protein related protein antibody; TAP-binding protein-like antibody; TAP-binding protein-related protein antibody; Tapasin like antibody; Tapasin R antibody; Tapasin Related Protein antibody; Tapasin-like antibody; TAPASIN-R antibody; Tapasin-related protein antibody; TAPBP L antibody; TAPBP R antibody; TAPBP-R antibody; Tapbpl antibody; TAPBPR antibody; TPSNR_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tapasin-related protein (201-468AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC).
  • 基因功能參考文獻:
    1. soluble TAPBPR, consisting of the luminal domain alone, added to intact cells, also functions as an effective peptide editor on surface MHC I molecules. PMID: 30213851
    2. this study reports the crystal structure of MHC I in complex with the peptide editor TAPBPR (TAP-binding protein-related), a tapasin homolog. PMID: 29025991
    3. this study presents the x-ray structure of the TAPBPR-MHC I complex, which delineates the central step of catalysis. PMID: 29025996
    4. The authors identify an interaction between TAPBPR and UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1), a folding sensor in the calnexin/calreticulin quality control cycle that is known to regenerate the Glc1Man9GlcNAc2 moiety on glycoproteins. The results suggest the formation of a multimeric complex, dependent on a conserved cysteine at position 94 in TAPBPR, in which TAPBPR promotes the association of UGT1 with p PMID: 28425917
    5. It is now clear there are two MHC class I specific peptide editors, tapasin and TAPBPR, intimately involved in controlling peptide presentation to the immune system. PMID: 26439010
    6. These results support a role of TAPBPR in stabilizing peptide-receptive conformation(s) of MHC-I, permitting peptide editing. PMID: 26869717
    7. TAPBPR is a new player in the MHC class I presentation pathway. (Review) PMID: 25720504
    8. The longer TAPBPR protein interacted with MHC class I but was attenuated in its ability to down-regulate surface expression of MHC class I. PMID: 24444341
    9. the data indicate that TAPBPR and tapasin bind in a similar orientation to the same face of MHC class I. PMID: 24163410
    10. The function of the tapasin-related protein, TAPBPR, was investigated. PMID: 23401559

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Mainly found in endoplasmic reticulum but a minority is found on the cell surface (PubMed:11920573).
  • 數據庫鏈接:

    HGNC: 30683

    OMIM: 607081

    KEGG: hsa:55080

    STRING: 9606.ENSP00000266556

    UniGene: Hs.504597



主站蜘蛛池模板: 亚洲性夜夜综合久久7777| 国产精品毛片av999999| 手机看片精品国产福利| 亚洲欧美日韩在线一区| 奇米影视7777久久精品| 18禁无遮挡免费视频网站| 黑人巨茎大战欧美白妇免费| 日本天天日噜噜噜| 国语少妇高潮对白在线| 国产精品亚洲аv久久| 丰满人妻被黑人猛烈进入| 欧美性生交大片18禁止| 国产又色又爽又黄好看的视频| 亚洲精品国产一区二区精华| 亚洲中文字幕无码久久2018| 欧美精品高清在线观看| 亚洲欧洲美洲无码精品va| 黄网站色成年片在线观看| 亚洲中文无码永久免| 日日摸日日碰夜夜爽av| 无码国产色欲xxxx视频| 国产亚洲色婷婷久久99精品| 最近中文字幕免费mv在线| 国产曰批免费视频播放免费| 国产精品宾馆在线精品酒店| 中文字幕无码不卡免费视频| 华人在线亚洲欧美精品| 大帝a∨无码视频在线播放| 色妞www精品视频| 亚洲精品第一国产综合野草社区 | 66lu国产在线观看| 国产精品自在在线午夜出白浆| 色婷婷五月综合激情中文字幕| 成人无码精品免费视频在线观看| 久久婷婷成人综合色| 欧美日韩不卡合集视频| 无码人妻一区二区三区四区av| 色欲综合一区二区三区| 色综合久久无码中文字幕| 黑人猛挺进小莹的体内视频| 国产xxx视频在线观看软件|