在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SWAP70 Antibody

  • 中文名稱:
    SWAP70兔多克隆抗體
  • 貨號:
    CSB-PA887026LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: SWAP70 antibody at 10µg/ml
      Lane 1: NIH/3T3 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Lane 3: Raji whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 69 kDa
      Observed band size: 69 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SWAP70 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SWAP70
  • 別名:
    KIAA0640 antibody; 70kDa antibody; AV235546 antibody; FLJ39540 antibody; HSPC321 antibody; SWA 70 protein antibody; SWAP 70 antibody; SWAP switching B-cell complex 70kDa subunit antibody; SWAP-70 antibody; SWAP70 antibody; Switch associated protein 70 antibody; Switch-associated protein 70 antibody; SWP70_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Switch-associated protein 70 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,SWAP70 Antibody (CSB-PA887026LA01HU),的標記方式是Non-conjugated。對于SWAP70 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA887026LB01HU SWAP70 Antibody, HRP conjugated ELISA
    FITC CSB-PA887026LC01HU SWAP70 Antibody, FITC conjugated
    Biotin CSB-PA887026LD01HU SWAP70 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
  • 基因功能參考文獻:
    1. Expression of switch-associated protein 70 is associated with lymphocyte activation and reduced disability in multiple sclerosis. PMID: 27495372
    2. These data show a key role for SWAP70 as a scaffold for tethering the peripheral actin cage to phagosomes. PMID: 27806292
    3. SWAP70 appears to act as a molecular intermediate between vGPCR and endothelial activation. PMID: 25889342
    4. SWAP70 may be a target of miR-145, and it might have a potential oncogenic function. PMID: 21360565
    5. Detection of SWAP70 antibodies during the attack period might suggest that SWAP70 is involved in Multiple Sclerosis relapse pathogenesis PMID: 22728961
    6. The unwinding of the C-terminal alpha-helix could regulate the functions of SWAP-70 at the plasma membrane surface. PMID: 22247562
    7. findings suggest that regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure PMID: 22210919
    8. protein that functions as the only B cell-specific component of an isotype switch recombination PMID: 11726218
    9. Overexpression of SWAP-70 altered the actin organization and lamellipodial morphology PMID: 12925760
    10. the binding activity of SWAP-70 to non-muscle F-actin is required for membrane ruffling. PMID: 16418221
    11. surface expression of SWAP-70 on HIV-1 infected cells as well as PBMCs; SWAP-70 may serve as a marker for T cell differentiation as well as for HIV-1 infection PMID: 16547421
    12. SWAP-70 may be involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates. PMID: 17371938

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cell membrane. Nucleus. Cell projection, lamellipodium. Cytoplasm, cytoskeleton.
  • 組織特異性:
    Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue. Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages.
  • 數據庫鏈接:

    HGNC: 17070

    OMIM: 604762

    KEGG: hsa:23075

    STRING: 9606.ENSP00000315630

    UniGene: Hs.153026



主站蜘蛛池模板: 99er国产这里只有精品视频免费| 中文字幕人妻熟女在线| 高h纯肉无码视频在线观看| 国产+日韩+另类+视频一区| 亚洲а∨天堂久久精品| 久久国内精品自在自线400部| 女女互磨互喷水高潮les呻吟| 99蜜桃在线观看免费视频网站| av蓝导航精品导航| 欧美另类bbbxxxxx另类| 亚洲日韩欧洲乱码av夜夜摸| 亚洲在线国产日韩欧美| 四虎成人欧美精品在永久在线| 国产jk白丝在线观看免费| 黑人大荫蒂老太大| 国产麻豆精品久久一二三| 97精品免费公开在线视频| 色综合天天综合网国产成人网| 精品国精品无码自拍自在线| 性强烈的欧美三级视频| 免费人成在线观看网站品爱网| 一本久久知道综合久久| 人禽无码视频在线观看| 无码国产一区二区三区四区| 久久精品99久久香蕉国产| 亚洲日韩中文字幕无码一区 | 亚洲色www永久网站| 中文字幕在线观看| 国产成人精品视觉盛宴| 国产又a又黄又潮娇喘视频| 亚洲欧美中文日韩在线v日本| 男女爽爽午夜18污污影院| 亚洲日本乱码中文在线电影 | 伊人久久久大香线蕉综合直播| 人与嘼交av免费| 国产精品成人免费999| 嫩草国产福利视频一区二区| 亚洲 中文字幕 日韩 无码| 成人亚洲精品久久久久| 亚洲狠狠爱综合影院网页| 天堂在线中文|