在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SWAP70 Antibody

SWAP70 Antibody

  • 中文名稱(chēng)：
    SWAP70兔多克隆抗體
  • 貨號(hào)：
    CSB-PA870303
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA870303(SWAP70 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CSB-PA870303(SWAP70 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SWAP70
  • 別名：
    KIAA0640 antibody; 70kDa antibody; AV235546 antibody; FLJ39540 antibody; HSPC321 antibody; SWA 70 protein antibody; SWAP 70 antibody; SWAP switching B-cell complex 70kDa subunit antibody; SWAP-70 antibody; SWAP70 antibody; Switch associated protein 70 antibody; Switch-associated protein 70 antibody; SWP70_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human SWAP70
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:10-1:50
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
  • 基因功能參考文獻(xiàn)：
    1. Expression of switch-associated protein 70 is associated with lymphocyte activation and reduced disability in multiple sclerosis. PMID: 27495372
    2. These data show a key role for SWAP70 as a scaffold for tethering the peripheral actin cage to phagosomes. PMID: 27806292
    3. SWAP70 appears to act as a molecular intermediate between vGPCR and endothelial activation. PMID: 25889342
    4. SWAP70 may be a target of miR-145, and it might have a potential oncogenic function. PMID: 21360565
    5. Detection of SWAP70 antibodies during the attack period might suggest that SWAP70 is involved in Multiple Sclerosis relapse pathogenesis PMID: 22728961
    6. The unwinding of the C-terminal alpha-helix could regulate the functions of SWAP-70 at the plasma membrane surface. PMID: 22247562
    7. findings suggest that regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure PMID: 22210919
    8. protein that functions as the only B cell-specific component of an isotype switch recombination PMID: 11726218
    9. Overexpression of SWAP-70 altered the actin organization and lamellipodial morphology PMID: 12925760
    10. the binding activity of SWAP-70 to non-muscle F-actin is required for membrane ruffling. PMID: 16418221
    11. surface expression of SWAP-70 on HIV-1 infected cells as well as PBMCs; SWAP-70 may serve as a marker for T cell differentiation as well as for HIV-1 infection PMID: 16547421
    12. SWAP-70 may be involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates. PMID: 17371938

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane. Nucleus. Cell projection, lamellipodium. Cytoplasm, cytoskeleton.
  • 組織特異性：
    Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue. Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17070

    OMIM: 604762

    KEGG: hsa:23075

    STRING: 9606.ENSP00000315630

    UniGene: Hs.153026



主站蜘蛛池模板： 狠狠色噜噜狠狠狠8888在| 久久96国产精品久久久| 亚洲综合另类小说色区| 亚洲国产精品成人影片久久| 亚洲欧美日韩一区在线观看| 国产成人青青久久大片| 亚洲色婷婷久久精品av蜜桃久久| 最新国产乱人伦偷精品免费网站| 精品一区二区三人妻视频 | 丁香狠狠色婷婷久久综合| 中文字幕一区二区三区乱码| xx性欧美肥妇精品久久久久久| _97夜夜澡人人爽人人喊_欧美| 久久毛片免费看一区二区三区| 久久99精品国产99久久6不卡| 国产亚洲精品久久久久久牛牛| 欧美z0zo人禽交欧美人禽交| 奇米777国产在线视频| 久久激情五月丁香伊人| 欧美精品videossex少妇| 97人妻人人揉人人躁人人| 污18禁污色黄网站免费| av片亚洲国产男人的天堂| 久久97精品久久久久久久不卡| 精品国产一区二区三区四区vr| 国产亚洲人成在线播放| 亚洲va中文字幕无码久久不卡| 影音先锋男人av鲁色资源网 | 欧美成人看片一区二区三区尤物| 亚洲色大网站www永久网站| 黄床片30分钟免费视频教程| 亚洲高清最新av网站| 国产av激情无码久久| 亚洲综合无码一区二区痴汉| 精品精品国产高清a毛片| 女人爽到高潮免费视频大全| 午夜性色福利在线观看视频| 丰满少妇做爰视频爽爽和| 亚洲中文字幕无码中文字在线| 国产成人免费无码av在线播放| 性av无码天堂vr专区|