在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STT3A Antibody

STT3A Antibody

  • 中文名稱：
    STT3A兔多克隆抗體
  • 貨號：
    CSB-PA022885GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    B5 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A antibody; FLJ27038 antibody; Integral membrane protein 1 antibody; Integral transmembrane protein 1 antibody; ITM1 antibody; MGC9042 antibody; Oligosaccharyl transferase subunit STT3A antibody; STT 3A antibody; STT3 subunit of the oligosaccharyltransferase complex homolog A antibody; STT3-A antibody; STT3A antibody; STT3A_HUMAN antibody; TMC antibody; Transmembrane protein TMC antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human STT3A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
  • 基因功能參考文獻：
    1. Study reports that STT3B-oligosaccharyltransferase, but not STT3A-oligosaccharyltransferase, is a lipid-linked oligosaccharide hydrolase. PMID: 30181269
    2. DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase STT3A and the endoplasmic reticulum translocon. PMID: 28860277
    3. This study showed that Congenital Disorder of Glycosylation Caused by Mutations in STT3A. PMID: 28424003
    4. Consensus sites containing large hydrophobic and negatively charged middle residues are frequently skipped by STT3A during protein translation. PMID: 25029371
    5. Results show homozygous mutation in STT3A and in STT3B causes congenital disorders of glycosylation. PMID: 23842455
    6. DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
    7. Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
    8. The STT3A OST isoform is primarily responsible for cotranslational glycosylation of the nascent polypeptide as it enters the lumen of the endoplasmic reticulum. PMID: 19167329

    顯示更多

    收起更多

  • 相關疾病：
    Congenital disorder of glycosylation 1W (CDG1W)
  • 亞細胞定位：
    Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    STT3 family
  • 組織特異性：
    Expressed at high levels in placenta, liver, muscle and pancreas, and at very low levels in brain, lung and kidney. Expressed in skin fibroblasts (at protein level).
  • 數據庫鏈接：

    HGNC: 6172

    OMIM: 601134

    KEGG: hsa:3703

    STRING: 9606.ENSP00000376472

    UniGene: Hs.504237



主站蜘蛛池模板： 成人三级视频在线观看一区二区| 亚洲日本一区二区一本一道| 日本不卡三区| 精品一区二区三人妻视频| 亚洲精品乱码一区二区三区| 亚洲一区二区三区国产精品无码| 亚洲精品黑牛一区二区三区| 欧美精品videosex性欧美| 中文无码精品a∨在线观看不卡| 越猛烈欧美xx00动态图| 色综合亚洲一区二区小说性色aⅴ| 国产精品亚洲二区在线观看| 久久久久久欧美精品se一二三四| 99热成人精品热久久6网站 | 日日摸日日碰夜夜爽亚洲| 精品国产第一国产综合精品| 国产综合久久久久| 色综合天天视频在线观看| 亚色九九九全国免费视频| 印度女人狂野牲交| 精品久久久久久中文字幕| 美女mm131爽爽爽作爱| 久久中文精品无码中文字幕下载| 又色又爽又高潮免费视频观看| 亚洲色婷婷六月亚洲婷婷6月| 黄网站色成年片在线观看| 日本欧美大码aⅴ在线播放| 中文字幕乱码免费| 伊人色综合久久天天五月婷| 日本国产网曝视频在线观看 | 国产成人精品福利一区二区三区| 国产精品va无码二区| 熟妇人妻av中文字幕老熟妇| 亚洲精品蜜桃久久久久久| 欧美日韓性视頻在線| 久久精品伊人久久精品伊人| 国产精品第一国产精品| 色欲久久人妻内射| 狠狠色噜噜狠狠狠狠色综合网| 亚洲色大成网站www尤物| 狼人大香伊蕉国产www亚洲|