在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STT3A Antibody

STT3A Antibody

  • 中文名稱：
    STT3A兔多克隆抗體
  • 貨號：
    CSB-PA022885GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    B5 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A antibody; FLJ27038 antibody; Integral membrane protein 1 antibody; Integral transmembrane protein 1 antibody; ITM1 antibody; MGC9042 antibody; Oligosaccharyl transferase subunit STT3A antibody; STT 3A antibody; STT3 subunit of the oligosaccharyltransferase complex homolog A antibody; STT3-A antibody; STT3A antibody; STT3A_HUMAN antibody; TMC antibody; Transmembrane protein TMC antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human STT3A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
  • 基因功能參考文獻：
    1. Study reports that STT3B-oligosaccharyltransferase, but not STT3A-oligosaccharyltransferase, is a lipid-linked oligosaccharide hydrolase. PMID: 30181269
    2. DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase STT3A and the endoplasmic reticulum translocon. PMID: 28860277
    3. This study showed that Congenital Disorder of Glycosylation Caused by Mutations in STT3A. PMID: 28424003
    4. Consensus sites containing large hydrophobic and negatively charged middle residues are frequently skipped by STT3A during protein translation. PMID: 25029371
    5. Results show homozygous mutation in STT3A and in STT3B causes congenital disorders of glycosylation. PMID: 23842455
    6. DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
    7. Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
    8. The STT3A OST isoform is primarily responsible for cotranslational glycosylation of the nascent polypeptide as it enters the lumen of the endoplasmic reticulum. PMID: 19167329

    顯示更多

    收起更多

  • 相關疾病：
    Congenital disorder of glycosylation 1W (CDG1W)
  • 亞細胞定位：
    Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    STT3 family
  • 組織特異性：
    Expressed at high levels in placenta, liver, muscle and pancreas, and at very low levels in brain, lung and kidney. Expressed in skin fibroblasts (at protein level).
  • 數據庫鏈接：

    HGNC: 6172

    OMIM: 601134

    KEGG: hsa:3703

    STRING: 9606.ENSP00000376472

    UniGene: Hs.504237



主站蜘蛛池模板： 人妻三级日本香港三级极| 999久久久国产精品消防器材| 在线观看国产精品电影| 狠狠色综合久久丁香婷婷| 日本人妻精品免费视频| 日本精品高清一区二区| 熟女人妻一区二区三区免费看| 日韩精品无码成人专区| 五月婷婷久久草| 蜜臀av在线观看| 人妻人人做人做人人爱| 六月丁香综合在线视频| 秋霞av在线露丝片av无码| 最近日本精品一卡2卡3卡4卡| 欧美精品免费观看二区| 国产乡下妇女做爰| 亲子乱av一区二区三区| 提莫影院av毛片入口| 国产卡一卡二无线乱码| 人妻无码久久精品人妻| 亚洲综合精品伊人久久| 国产精品爽爽ⅴa在线观看| 国产精品久久久久一区二区三区 | 国产明星xxxx色视频| 国产精品久久久久久亚洲毛片| 装睡被陌生人摸出水好爽| 午夜男女爽爽影院免费视频| 欧美乱码卡一卡二卡三新区| 欧美人与动牲猛交a欧美精品| 日韩av高清无码| 中文无码精品a∨在线观看| 四虎永久地址www成人久久| 无码毛片内射白浆视频| 一本一道色欲综合网中文字幕| 亚洲一区二区三区波多野结衣| 在线观看片a免费不卡观看| 男女猛烈xx00免费视频试看| 风流少妇按摩来高潮| 国产成 人 综合 亚洲网站| 国产精品系列无码专区| 一进一出抽搐gif|