在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STT3A Antibody

STT3A Antibody

  • 中文名稱：
    STT3A兔多克隆抗體
  • 貨號：
    CSB-PA022885LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA022885LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) STT3A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    B5 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A antibody; FLJ27038 antibody; Integral membrane protein 1 antibody; Integral transmembrane protein 1 antibody; ITM1 antibody; MGC9042 antibody; Oligosaccharyl transferase subunit STT3A antibody; STT 3A antibody; STT3 subunit of the oligosaccharyltransferase complex homolog A antibody; STT3-A antibody; STT3A antibody; STT3A_HUMAN antibody; TMC antibody; Transmembrane protein TMC antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A protein (39-114AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，STT3A Antibody (CSB-PA022885LA01HU)，的標記方式是Non-conjugated。對于STT3A Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA022885LB01HU STT3A Antibody, HRP conjugated ELISA
    FITC CSB-PA022885LC01HU STT3A Antibody, FITC conjugated
    Biotin CSB-PA022885LD01HU STT3A Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient post-translational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
  • 基因功能參考文獻：
    1. Study reports that STT3B-oligosaccharyltransferase, but not STT3A-oligosaccharyltransferase, is a lipid-linked oligosaccharide hydrolase. PMID: 30181269
    2. DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase STT3A and the endoplasmic reticulum translocon. PMID: 28860277
    3. This study showed that Congenital Disorder of Glycosylation Caused by Mutations in STT3A. PMID: 28424003
    4. Consensus sites containing large hydrophobic and negatively charged middle residues are frequently skipped by STT3A during protein translation. PMID: 25029371
    5. Results show homozygous mutation in STT3A and in STT3B causes congenital disorders of glycosylation. PMID: 23842455
    6. DDIT3, STT3A, ARG2 and FAM129A immunohistochemistry does not appear to be useful in the diagnosis of thyroid follicular neoplasias, as they do not reliably distinguish follicular thyroid carcinoma from follicular thyroid adenoma. PMID: 22157935
    7. Gene-expression data suggest a difference in expression between STT3A, Clorf24, and TFF3 in FAs versus carcinomas that may be detected from an FNA sample. Findings must be validated from preoperative FNAs in larger numbers PMID: 21520112
    8. The STT3A OST isoform is primarily responsible for cotranslational glycosylation of the nascent polypeptide as it enters the lumen of the endoplasmic reticulum. PMID: 19167329

    顯示更多

    收起更多

  • 相關疾病：
    Congenital disorder of glycosylation 1W (CDG1W)
  • 亞細胞定位：
    Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    STT3 family
  • 組織特異性：
    Expressed at high levels in placenta, liver, muscle and pancreas, and at very low levels in brain, lung and kidney. Expressed in skin fibroblasts (at protein level).
  • 數據庫鏈接：

    HGNC: 6172

    OMIM: 601134

    KEGG: hsa:3703

    STRING: 9606.ENSP00000376472

    UniGene: Hs.504237



主站蜘蛛池模板： 亚洲熟妇无码av不卡在线播放| 国产精品久久综合免费| 不卡无码人妻一区三区音频| 国产精品一区二区av交换| 蜜臀av无码精品人妻色欲| 无码人妻精品一区二区三区久久久| 国产97公开成人免费视频在线观看 | 亚洲天堂在线观看完整版| 露脸叫床粗话东北少妇| 精品国精品无码自拍自在线| 亚洲精品无码mv在线观看| 中文字幕精品亚洲无线码vr| 亚洲线精品一区二区三区| 牛牛在线视频| 在线亚洲日产一区二区| 中文字幕一区日韩精品| 青青草视频在线观看| 久久欧美国产伦子伦精品| 欧洲无码精品a码无人区| 女人被爽到高潮视频免费国产| 欧美牲交a欧美牲交aⅴ免费真 | 亚洲成av人片不卡无码久久 | 日韩 欧美 动漫 国产 制服| 中文在线中文a| 久久亚洲精品无码av宋| 国产又黄又爽又色的免费视频 | 亚洲精品久久国产精品浴池| 亚洲精品乱码久久久久久按摩 | 精品一区二区三区免费播放| 亚洲午夜久久久久妓女影院| 久久高清超碰av热热久久| 夜夜躁很很躁日日躁麻豆| 欧美激情精品久久久久久| 55夜色66夜色国产精品视频 | 国产 在线 | 日韩| 午夜男女爽爽影院免费视频| 国产亚洲精品在av| 男女猛烈无遮挡免费视频| av无码久久久久不卡蜜桃| 公与淑婷厨房猛烈进出视频免费| 午夜视频体内射.com.com|