在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STEAP3 Antibody

STEAP3 Antibody

  • 中文名稱：
    STEAP3兔多克隆抗體
  • 貨號：
    CSB-PA717655LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: STEAP3 antibody at 24µg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 55, 56, 51 kDa
      Observed band size: 55 kDa
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA717655LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA717655LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) STEAP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    STEAP3; TSAP6; Metalloreductase STEAP3; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Metalloreductase STEAP3 protein (1-207AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，STEAP3 Antibody (CSB-PA717655LA01HU)，的標記方式是Non-conjugated。對于STEAP3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA717655LB01HU STEAP3 Antibody, HRP conjugated ELISA
    FITC CSB-PA717655LC01HU STEAP3 Antibody, FITC conjugated
    Biotin CSB-PA717655LD01HU STEAP3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
  • 基因功能參考文獻：
    1. In hepatocellular carcinoma (HCC), lower expression of the STEAP3 copper reductase and heavy Cu isotope enrichment have been reported for the tumor mass, relative to the surrounding tissue PMID: 28303916
    2. TSAP6 over expression is associated with poor survival in metastatic high-grade serous carcinoma. PMID: 27825812
    3. heterozygous STEAP3 mutations are relatively common in humans and that their deleterious effect in humans remains to be confirmed PMID: 26675350
    4. TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis. PMID: 22624035
    5. findings indicate that STEAP3 maintains iron storage in human malignant cells and tumor proliferation under the hypoferric condition PMID: 21871451
    6. TSAP6 may augment Myt1 activity and act downstream to p53 to interface apoptosis and cell-cycle progression PMID: 12606722
    7. role for TSAP6 in the export of TCTP and indicate that this multipass membrane protein could have a general role in the regulation of vesicular trafficking and secretion. PMID: 15319436
    8. The crystal structure of the human Steap3 oxidoreductase domain in the absence and presence of NADPH was determined. PMID: 18495927
    9. Down-regulated expression of the TSAP6 protein in liver is associated with a transition from cirrhosis to hepatocellular carcinoma PMID: 19236508

    顯示更多

    收起更多

  • 相關疾病：
    Anemia, hypochromic microcytic, with iron overload 2 (AHMIO2)
  • 亞細胞定位：
    Endosome membrane; Multi-pass membrane protein. Note=Localizes to vesicular-like structures at the plasma membrane and around the nucleus.
  • 蛋白家族：
    STEAP family
  • 組織特異性：
    Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.
  • 數據庫鏈接：

    HGNC: 24592

    OMIM: 609671

    KEGG: hsa:55240

    STRING: 9606.ENSP00000376822

    UniGene: Hs.647822



主站蜘蛛池模板： 国产精品禁18久久久夂久| 久久久一本精品久久精品六六| 日韩成人无码一区二区三区| 精品久久久久久中文字幕202| 国内午夜国产精品小视频| 欧美性生交xxxxx久久久| 日韩激情无码不卡码| 日韩放荡少妇无码视频| 无码av岛国片在线播放| 欧美丰满一区二区免费视频 | 丰满人妻熟妇乱又伦精品| 日本在线视频www色| 欧洲无线码免费一区| 国产福利在线视频蜜芽tv| 女人爽得直叫免费视频| 国产成人午夜精华液 | 硬了进去湿好大娇喘视频 | 无码日韩人妻av一区免费| 亚洲中文字幕在线无码一区二区| 窝窝影院午夜看片| 人妻av中文系列| 久久久久国产精品熟女影院| 日日摸日日碰夜夜爽无| 国产精品亚洲五月天高清| 自拍偷在线精品自拍偷无码专区| 无码超乳爆乳中文字幕| 99这里有精品视频视频| 国产做爰xxxⅹ高潮视频12p| 人人妻人人狠人人爽| 人妻丰满熟妇岳av无码区hd| 国产在线98福利播放视频| 青青青国产在线观看免费| 国产精品成人a区在线观看| 乱中年女人伦| 久久久久国产精品无码免费看| 茄子视频国产在线观看| 亚洲精品久久国产精品| 丰满护士巨好爽好大乳| 麻豆乱码国产一区二区三区| 无码爆乳护士让我爽| 亚洲日韩精品无码专区加勒比海 |