在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. STEAP3 Antibody, FITC conjugated

STEAP3 Antibody, FITC conjugated

  • 中文名稱：
    STEAP3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA717655LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) STEAP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    STEAP3; TSAP6; Metalloreductase STEAP3; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Metalloreductase STEAP3 protein (1-207AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
  • 基因功能參考文獻：
    1. In hepatocellular carcinoma (HCC), lower expression of the STEAP3 copper reductase and heavy Cu isotope enrichment have been reported for the tumor mass, relative to the surrounding tissue PMID: 28303916
    2. TSAP6 over expression is associated with poor survival in metastatic high-grade serous carcinoma. PMID: 27825812
    3. heterozygous STEAP3 mutations are relatively common in humans and that their deleterious effect in humans remains to be confirmed PMID: 26675350
    4. TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis. PMID: 22624035
    5. findings indicate that STEAP3 maintains iron storage in human malignant cells and tumor proliferation under the hypoferric condition PMID: 21871451
    6. TSAP6 may augment Myt1 activity and act downstream to p53 to interface apoptosis and cell-cycle progression PMID: 12606722
    7. role for TSAP6 in the export of TCTP and indicate that this multipass membrane protein could have a general role in the regulation of vesicular trafficking and secretion. PMID: 15319436
    8. The crystal structure of the human Steap3 oxidoreductase domain in the absence and presence of NADPH was determined. PMID: 18495927
    9. Down-regulated expression of the TSAP6 protein in liver is associated with a transition from cirrhosis to hepatocellular carcinoma PMID: 19236508

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Anemia, hypochromic microcytic, with iron overload 2 (AHMIO2)
  • 亞細胞定位：
    Endosome membrane; Multi-pass membrane protein. Note=Localizes to vesicular-like structures at the plasma membrane and around the nucleus.
  • 蛋白家族：
    STEAP family
  • 組織特異性：
    Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.
  • 數據庫鏈接：

    HGNC: 24592

    OMIM: 609671

    KEGG: hsa:55240

    STRING: 9606.ENSP00000376822

    UniGene: Hs.647822



主站蜘蛛池模板： 久久伊人蜜桃av一区二区| 99久久国产综合精品swag| 婷婷开心激情综合五月天| 久久久久免费看成人影片| 精品无码中文字幕在线| 亚洲国产欧美日韩精品一区二区三区 | 亚洲精品乱码久久久久久日本 | 影音先锋在线亚洲网站| 亚洲欧美人成网站在线观看看| 日本日本熟妇中文在线视频| 国产精品区av| 苍井空张开腿实干12次| 少妇与黑人一二三区无码| 天天做天天爱夜夜爽毛片| 国产男女嘿咻视频在线观看| 国产高清国产精品国产专区| 欧美丰满少妇xxxxx| 无码h片在线观看网站| 国产一区二区三区在线蜜桃| 久久精品国产99久久久小说| 久久经精品久久精品免费观看| 人妻丰满熟妇岳av无码区hd | 国产高清av首播原创麻豆| 国产欧美va欧美va香蕉在线观看| 国产无遮挡色视频免费观看性色| 亚洲无线码免费| 永久免费无码网站在线观看| 丁香色婷婷国产精品视频| 亚洲乱码一区二三四区ava | 国产成人午夜福利在线观看| 97色伦综合在线欧美视频| 欧美成人无码a区视频在线观看| 亚洲精品nv久久久久久久久久 | 国产精品久久久久久影视| 亚洲色大网站www永久网站| 国产在线精品欧美日韩电影| 大黑人交xxxx18视频| 免费国精产品—品二品| 秋霞鲁丝片av无码| 国产成人午夜福利电影在线播放| 国产凹凸在线一区二区|