在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

STAG3 Antibody

  • 中文名稱:
    STAG3兔多克隆抗體
  • 貨號(hào):
    CSB-PA167892
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from Jurkat cells, using STAG3 antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) STAG3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    STAG3
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from C-terminal of Human STAG3.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
  • 基因功能參考文獻(xiàn):
    1. c.677C > G associated with primary ovarian insufficiency PMID: 28802712
    2. Loss of STAG2 or STAG3, which encode subunits of the cohesin complex, in melanoma cells results in resistance to BRAF inhibitors (BRAFi). Loss-of-function mutations in STAG2, as well as decreased expression of STAG2 or STAG3 proteins were found in several tumor samples from patients with acquired resistance to BRAFi and in BRAFi-resistant melanoma cell lines. PMID: 27500726
    3. STAG3 truncating variant as the cause of primary ovarian insufficiency has been found in two sisters in a consanguineous Lebanese family. PMID: 26059840
    4. We identified a homozygous 1-bp deletion inducing a frameshift mutation in STAG3 on chromosome 7. Female mice devoid of Stag3 are sterile. PMID: 24597867
    5. we show evidence for the involvement of a common allele of STAG3 in the development of epithelial ovarian cancer PMID: 20635389
    6. identified as one of five genes containing 11 somatic mutations in a panel that included 132 colorectal cancers, then demonstrated that down-regulation of such homologs resulted in chromosomal instability and chromatid cohesion defects in human cells PMID: 18299561
    7. plays a role in regulation of transcription due to genetic imprinting, sister chromatid exchange, chromosome segregation and as an insulator element. (review) PMID: 18788457

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Premature ovarian failure 8 (POF8)
  • 亞細(xì)胞定位:
    Nucleus. Chromosome. Chromosome, centromere.
  • 蛋白家族:
    SCC3 family
  • 組織特異性:
    Testis specific.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11356

    OMIM: 608489

    KEGG: hsa:10734

    STRING: 9606.ENSP00000319318

    UniGene: Hs.592283



主站蜘蛛池模板: 777米奇色狠狠俺去啦| 内射巨臀欧美在线视频| 永久免费毛片在线播放| 麻豆精品久久久久久中文字幕无码 | 国产乱子伦三级在线播放| 日本午夜免a费看大片中文4| 亚洲人成日韩中文字幕无卡| 日本伊人精品一区二区三区| 亚洲一线二线三线写真| 51被公侵犯玩弄漂亮人妻| 96亚洲精华国产精华精华液| 久久精品蜜芽亚洲国产av| 成人性做爰aaa片免费看| 中文乱码字幕高清一区二区| 久久不见久久见www电影免费| 亚洲 小说区 图片区 都市| 无码人妻丰满熟妇区毛片18 | 国产亚洲中文字幕在线制服| 又白又嫩毛又多15p| 国产午夜精品无码| 欧洲av成本人在线观看免费| 中文字幕va一区二区三区| 蜜臀av夜夜澡人人爽人人| 女人张开腿让男人桶爽| 亚洲国产超清无码专区| 特级做a爰片毛片免费看| 摸丰满大乳奶水www免费| 精品国产一区二区三区麻豆| 天天爱天天做久久狼狼| 又粗又大内射免费视频小说| 国产在线 | 欧洲| 欧美大胆作爱视频欣赏人体| 国产亚洲精久久久久久无码| 苍井空亚洲精品aa片在线播放| 久久久www成人免费看片| 色噜噜狠狠色综合av| 精品福利一区二区三区免费视频| 久久av无码aⅴ高潮av喷吹| 伊人精品成人久久综合97| 少妇性bbb搡bbb爽爽爽欧美| 男女同房做爰爽免费|