在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ST6GALNAC2 Antibody, FITC conjugated

ST6GALNAC2 Antibody, FITC conjugated

  • 中文名稱：
    ST6GALNAC2兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA883452LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ST6GALNAC2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ST6GALNAC2
  • 別名：
    ST6GALNAC2 antibody; SIAT7B antibody; SIATL1 antibody; STHMAlpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 antibody; EC 2.4.99.3 antibody; GalNAc alpha-2,6-sialyltransferase II antibody; ST6GalNAc II antibody; ST6GalNAcII antibody; SThM antibody; Sialyltransferase 7B antibody; SIAT7-B antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 protein (101-374AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of N-acetylneuraminyl groups onto glycan chains in glycoproteins.
  • 基因功能參考文獻(xiàn)：
    1. MicroRNAs miR-135b and miR-182 may reverse the resistance to 5-fluorouracil (5-FU) in colorectal cancer (CRC) cells by targeting ST6GALNAC2 via PI3K/AKT pathway, which render potential chemotherapy targets for the treatment of CRC. PMID: 28767179
    2. miR-182/-135b/ST6GALNAC2/PI3K/AKT axis could function as regulator of progression in colorectal cancer PMID: 29030743
    3. Study provides evidence that mutations in B3GNT2, B4GALT2, and ST6GALNAC2 underlie aberrant glycosylation, and contribute to the pathogenesis of molecular subsets of colon and other gastrointestinal malignancies. PMID: 27004849
    4. Results provide evidence that ST6GalNAcII activated the invasion in follicular thyroid cancer cells through regulating the activity of PI3K/Akt pathway. PMID: 26820593
    5. High expression level of ST6GalNAcII is associated with invasive phenotype of breast cancer. PMID: 24756995
    6. ST6GalNAc II might be participated in the glycosylation of Axl, and this Axl glycosylation may mediate the tumorigenicity, invasion, and distant metastasis of breast phyllodes tumor cells. PMID: 24961352
    7. Results identified the sialyltransferase ST6GalNAc2 as a novel breast cancer metastasis suppressor. PMID: 24520024
    8. Il-6 and Il-4 reduced galactosylation of the O-glycan substrate directly via decreased expression of the galactosyltransferase C1GalT1 and, indirectly, via increased expression of the sialyltransferase ST6GalNAc-II PMID: 24398680
    9. ST6GalNAc2 is a novel enzyme that regulates leukocyte adhesion under fluid shear PMID: 23548905
    10. Expression of the ST6-GalNAcII gene and activity of the CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase were higher in immunoglobulinA1-producing cell lines. PMID: 17418236
    11. the ADG haplotype in the ST6GALNAC2 gene is a functional regulatory variant that may contribute to the genetic susceptibility in a subset of patients in whom the desialylation of IgA1 molecules was the main causative pathogenesis of IgAN PMID: 17480010
    12. reduced sialylation of serum IgA1 may result from decreased expression of ST6GALNAC2. PMID: 19170967
    13. potential genetic interactions of C1GALT1 and ST6GALNAC2 variants influence IgA1 O-glycosylation, disease predisposition, and disease severity, and may contribute to the polygenic nature of IgA nephropathy PMID: 19357720

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 29 family
  • 組織特異性：
    Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10867

    OMIM: 610137

    KEGG: hsa:10610

    STRING: 9606.ENSP00000225276

    UniGene: Hs.592105



主站蜘蛛池模板： 蜜臀av 国内精品久久久| 国产熟女精品视频大全| 久久精品国产亚洲夜色av网站| 一本久久伊人热热精品中文字幕 | 国产精品一区二区久久不卡| 午夜精品一区二区三区免费视频 | 欧美日韩亚洲国产在线制服| 国产欧美精品区一区二区三区| 99精品电影一区二区免费看| 国产精品一卡二卡三卡| 丰满护士巨好爽好大乳| 3d动漫精品啪啪一区二区中| 美女扒开腿让男人桶爽app免费看| 亚洲国产品综合人成综合网站| 久久精品99国产精品日本| 在线观看国产一区二区三区| 久久久国产精品消防器材| 久久精品国产99久久香蕉 | 国产两女互慰高潮视频在线观看| 色中色成人导航| 亚洲欧洲自拍拍偷午夜色 | 亚洲日韩性欧美中文字幕| 97国产在线看片免费人成视频| 亚洲午夜未满十八勿入| 无码国产成人午夜电影在线观看| 一个人看的www免费视频在线观看| 香港台湾经典三级a视频| 亚洲精品国产成人一区二区| 免费无码又爽又刺激软件下载| 国产精品禁18久久久夂久 | 使劲快高潮了国语对白在线| 中文人妻av久久人妻18| 九九久久精品免费观看| 18禁无遮挡羞羞污污污污网站| 亚洲成a人片在线观看你懂的| 久久中文字幕人妻熟av女| 国产人与禽zoz0性伦| 久久久久久人妻毛片a片| 老子影院午夜伦不卡无码| 夜夜高潮夜夜爽国产伦精品| 国产三级久久久精品麻豆三级|