在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SSX2IP Antibody

SSX2IP Antibody

  • 中文名稱：
    SSX2IP兔多克隆抗體
  • 貨號：
    CSB-PA938404
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA938404(SSX2IP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA938404(SSX2IP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ADIP antibody; ADIP_HUMAN antibody; Afadin and alpha actinin binding protein antibody; Afadin DIL domain interacting protein antibody; Afadin DIL domain-interacting protein antibody; Afadin- and alpha-actinin-binding protein antibody; FLJ10848 antibody; KIAA0923 antibody; MGC75026 antibody; OTTHUMP00000011574 antibody; SSX 2 interacting protein antibody; SSX2 interacting protein antibody; SSX2-interacting protein antibody; SSX2IP antibody; Synovial sarcoma X breakpoint 2 interacting protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human SSX2IP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:30-1:150
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling. Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Involved in ciliogenesis. It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia.
  • 基因功能參考文獻：
    1. This study determined the crystallographic structure of human Afadin in complex with LGN. PMID: 26751642
    2. Studied afadin in complex with beta-catenin in glomeruli and in cultured mesangial cells. Found expression of afadin at mesangial intercellular junctions was greatly decreased in mesangial proliferative nephritis in rats & patients w/glomerulonephritis. PMID: 26568295
    3. Knockdown of Wdr8 or hMsd1/SSX2IP displayed very similar mitotic defects, in which spindle microtubules became shortened and misoriented. PMID: 26545777
    4. SSX2IP-mediated microtubule anchoring is essential for proper centriole assembly and duplication. On SSX2IP knockdown, the centriolar satellites become stuck at the microtubule minus end near the centrosome. PMID: 25833712
    5. results showed that SSX2IP promotes the development and metastasis of hepatocellular carcinoma and contributes to the drug resistance of hepatoma cells PMID: 23452395
    6. Nuclear protein SS2IP interacts with cancer-related protein SSX2 and the human homologue of a Ras-like GTPase interactor, RABIN3. PMID: 12007189
    7. data shows that SSX2IP is affected in two ways that relate to the cell cycling of acute myeloid leukaemia cells PMID: 18028484

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, adherens junction. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    ADIP family
  • 組織特異性：
    Widely expressed, with the highest expression in brain, intermediate expression in kidney, testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no expression in pancreas and spleen. All specific brain
  • 數據庫鏈接：

    HGNC: 16509

    OMIM: 608690

    KEGG: hsa:117178

    STRING: 9606.ENSP00000340279

    UniGene: Hs.22587



主站蜘蛛池模板： 无人区码一码二码w358cc| 国产精品第12页| 免费无码va一区二区三区 | 精品欧美h无遮挡在线看中文| 成人免费视频在线观看地区免下载| 成人做爰www网站视频下载| 国产成人精品久久| 免费观看激色视频网站| 天天做av天天爱天天爽| 无码熟熟妇丰满人妻porn| 久久国产中文娱乐网| 夜夜爽夜夜叫夜夜高潮漏水| 中文字幕中文有码在线| 大伊香蕉精品视频在线直播| 精品久久久无码人妻中文字幕 | 精品国产午夜福利在线观看 | 直接观看黄网站免费视频| 又粗又硬又黄又爽的视频永久| 午夜男女xx00视频福利| 欧美一区二区| 亚洲精品久久久久高潮| 免费1级做爰片在线观看爱| 久久精品国产丝袜人妻| 成人网站免费大全日韩国产| 国产精品欧美成人片| 国产高清不卡一区二区| 日本最大色倩网站www| 国产真实伦在线观看视频| 欧美老肥妇多毛xxxxx| 播放灌醉水嫩大学生国内精品| 女人张开腿让男人桶爽| 人妻少妇精品无码专区芭乐视网| 精品国产福利拍拍拍| 国产精品久久久久久久久久久久| 性色欲情网站| 麻豆精品久久久久久中文字幕无码| 隔壁人妻偷人bd中字| 久久伊人精品波多野结衣 | 国产白丝精品爽爽久久蜜臀| 免费无码专区在线视频| 精品久久久久久无码中文野结衣|