在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SRSF6 Antibody

  • 中文名稱:
    SRSF6兔多克隆抗體
  • 貨號:
    CSB-PA021158GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    SRSF6
  • 別名:
    arginine/serine-rich 6 antibody; B52 antibody; Epididymis secretory protein Li 91 antibody; fc17h09 antibody; HEL S 91 antibody; MGC128807 antibody; MGC5045 antibody; Pre mRNA splicing factor SRP55 antibody; Pre-mRNA-splicing factor SRP55 antibody; Serine/arginine-rich splicing factor 6 antibody; SFRS6 antibody; Splicing factor antibody; Splicing factor arginine/serine rich 55 kDa antibody; Splicing factor arginine/serine rich 6 antibody; SR splicing factor 6 antibody; SRP55 antibody; SRSF6 antibody; SRSF6_HUMAN antibody; wu:faa54g02 antibody; wu:fc17h09 antibody; zgc:103497 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SFRS6
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
  • 基因功能參考文獻:
    1. Data suggest that regulation of pancreatic beta-cell function and survival/apoptosis involves alternative splicing modulated by key splicing regulator SRP55; SRP55-regulated alternative splicing includes modulation of function of pro-apoptotic proteins (BIM, BAX), JNK signaling, and endoplasmic reticulum stress. (BIM = BCL-2 interacting protein BIM; BAX = apoptosis regulator BAX) PMID: 29246973
    2. The recent studies suggest that correcting the SRSF6-driven missplicing and/or microtubule-associated imbalance might be of therapeutic value in Huntington's disease. PMID: 27529534
    3. LINC01133 inhibits epithelial mesenchymal transformation and metastasis in colorectal neoplasms by directly binding to SRSF6 as a target mimic. PMID: 27443606
    4. SRSF6 is a regulator of wound healing and tissue homeostasis in skin. PMID: 24440982
    5. Zinc inhibits the activity of SRSF6 and promotes elimination of exon 4, leading to preferential generation of BimS. PMID: 23648111
    6. The splicing factor SRSF6 is an oncoprotein that regulates the proliferation and survival of lung and colon cancer cells. PMID: 23132731
    7. Phosphorylation of SRp55 by Dyrk1A suppressed its ability to promote Tau exon 10 inclusion. PMID: 22767602
    8. Report upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors. PMID: 22516966
    9. SRp55 aids in the generation of partially spliced and unspliced HIV-1 mRNAs. PMID: 21345357
    10. interacts with calcitonin/CGRP exon 4 exonic splice enhancer(ESE); binding of SRp55 to an ESE required for calcitonin mRNA splicing suggests that the different levels of SRp55 in different cell types may regulate calcitonin/CGRP alternative splicing PMID: 12531473
    11. SRp55 binding to a suboptimal RNA binding site in the calcitonin/CGRP pre-mRNA exonic splice enhancer, or increasing the amount of SRp55 in cells, is required for calcitonin mRNA production. PMID: 12549914
    12. Higher relative expression of SR55 protein in breast tumors was associated with altered pattern of CD44 variants incorporating exon v7 PMID: 12779084
    13. These findings show that modulation of splicing activity in p53-deficient cells during the early response to sub-lethal DNA damage results in a change in the splicing of target genes, thus modifying the cellular response to genotoxic agents. PMID: 18571879

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus speckle.
  • 蛋白家族:
    Splicing factor SR family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10788

    OMIM: 601944

    KEGG: hsa:6431

    STRING: 9606.ENSP00000244020

    UniGene: Hs.684950



主站蜘蛛池模板: 人妻少妇-嫩草影院| 丰满人妻精品国产99aⅴ| 欧美性xxxxx极品老少| 亚洲精品一区中文字幕乱码| 无码av最新无码av专区| 亚洲精品无码久久久影院相关影片| 好吊射视频988gaocom| 柠檬福利第一导航在线| 国内精品九九久久精品| 久热这里只有精品视频6| 热99re久久精品国产首页免费| 性欧美俄罗斯乱妇| 极品少妇高潮到爽| 日韩人妻无码一区二区三区| 欧美午夜理伦三级在线观看| 99久久精品午夜一区二区 | 久久不见久久见www电影免费| 亚洲精品色午夜无码专区日韩| 伊人久久综合成人网| 成人无码视频97免费| 日韩亚洲国产高清免费视频| 国产佗精品一区二区三区| 韩产日产国产欧产| 亚洲人成无码区在线观看 | 久久激情五月丁香伊人| 播放灌醉水嫩大学生国内精品 | 国产成人麻豆精品午夜福利在线| 国产成人亚洲综合图区| 亚洲成a人无码| 亚洲熟悉妇女xxx妇女av| 国产午夜精品一区二区三区老| 久久人人97超碰caoporen | 人人添人人澡人人澡人人人人| 精品黑人一区二区三区久久| 真人性生交免费视频| 被窝的午夜无码福利专区| 999久久久国产精品| 精品一区二区三区东京热| 日本丰满岳乱妇在线观看 | 免费人成视频x8x8| 中文乱码人妻系列一区二区|