在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SRGAP1 Antibody

  • 中文名稱:
    SRGAP1兔多克隆抗體
  • 貨號(hào):
    CSB-PA948154
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA948154(SRGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA948154(SRGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hepg2 cells, TM4 cells, 293T cells, NIH/3T3 cells, Primary antibody: CSB-PA948154(SRGAP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    SRGAP1
  • 別名:
    4930572H05Rik antibody; ARHGAP13 antibody; FLJ22166 antibody; KIAA1304 antibody; RGD1566260 antibody; Rho GTPase activating protein 13 antibody; Rho GTPase-activating protein 13 antibody; SLIT ROBO Rho GTPase activating protein 1 antibody; SLIT-ROBO Rho GTPase-activating protein 1 antibody; SRGAP 1 antibody; srGAP1 antibody; SRGP1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human SRGAP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
  • 基因功能參考文獻(xiàn):
    1. Results show that the protein expression of srGAP1 is remarkably decreased in 47.5% of colorectal cancer (CRC) tissues compared and is found to be associated with tumor progression and poor prognosis. PMID: 27923383
    2. we identified a consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P(meta) = 1.14 x 10(-7)) PMID: 25134534
    3. Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract PMID: 26026792
    4. The elevated miR-145 present in invasive glioblastoma cells (IM3 cells) targets and down-regulated srGAP1, thereby allowing downstream G-proteins to remain in their active state and promote the observed invasive phenotype PMID: 26026080
    5. The interaction of betaPix with srGAP1 is critical for maintaining suppressive crosstalk between Cdc42 and RhoA during 3D collagen migration. PMID: 25150978
    6. Data indicate that srGAP1 possesses a GAP activity specific to Rac1 and is recruited to lamellipodia in a Rac1-dependent manner. PMID: 24006490
    7. genome-wide linkage analysis in populations in Ohio and Poland: Data suggest that missense mutations in SRGAP1 are associated with genetic predisposition to papillary thyroid carcinoma. PMID: 23539728
    8. This study proposed that the expression of SRGAP1 in the anterior neocortex may mark the early location of the human motor cortex, including its corticospinal projection neurons, allowing further study of their early differentiation. PMID: 21060114
    9. FNBP2, ARHGAP13, ARHGAP14 and ARHGAP4 constitute the FNBP2 family characterized by FCH, RhoGAP and SH3 domains. PMID: 12736724

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Thyroid cancer, non-medullary, 2 (NMTC2)
  • 組織特異性:
    Expressed in brain, lung, kidney, and testis.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 17382

    OMIM: 188470

    KEGG: hsa:57522

    STRING: 9606.ENSP00000347198

    UniGene: Hs.210751



主站蜘蛛池模板: 久热这里只有精品99在线观看 | 香草乱码一二三四区别| 无码人妻在线一区二区三区免费| 免费一区二区无码东京热| 狠狠色狠狠色综合网| 人妻无码视频一区二区三区| а√中文在线资源库| av一区二区三区人妻少妇| 激情综合五月丁香亚洲| 亚洲精品国产av成拍色拍婷婷 | 国产一线二线三线女| 北条麻妃一区二区三区av高清| 在线亚洲精品国产一区麻豆| 亚洲色无码专区一区| 中文字幕 亚洲精品 第1页| 欧美老妇交乱视频在线观看| 国产伦子沙发午休系列资源曝光| 一本大道久久东京热av| 无码人妻一区二区三区免费n鬼逝| 久久精品亚洲中文字幕无码网站 | 亚洲精品久久久久久久蜜桃| 欧美高清freexxxx性| 亚洲高清无码加勒比| 亚洲欧美中文字幕日韩一区二区 | 亚洲国产精品久久久久网站| 国产无遮挡18禁无码网站免费| 国产婷婷色综合av蜜臀av| 老太脱裤子让老头玩xxxxx| 成人午夜高潮刺激免费视频| 欲女熟妇国产一区二区| 国产精品久久久久久久久久久久人四虎 | 人人妻人人澡人人爽精品欧美| 乱色熟女综合一区二区三区| 亚洲欧美韩国综合色| 久久精品高清一区二区三区| 大伊香蕉精品视频在线 | 天干夜天干天天天爽视频| 国产免费视频| 乱码视频午夜间在线观看| 尹人香蕉99久久综合网站| 亚洲熟女乱色一区二区三区|