在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SRGAP1 Antibody

SRGAP1 Antibody

  • 中文名稱：
    SRGAP1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA948154
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA948154(SRGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA948154(SRGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hepg2 cells, TM4 cells, 293T cells, NIH/3T3 cells, Primary antibody: CSB-PA948154(SRGAP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SRGAP1
  • 別名：
    4930572H05Rik antibody; ARHGAP13 antibody; FLJ22166 antibody; KIAA1304 antibody; RGD1566260 antibody; Rho GTPase activating protein 13 antibody; Rho GTPase-activating protein 13 antibody; SLIT ROBO Rho GTPase activating protein 1 antibody; SLIT-ROBO Rho GTPase-activating protein 1 antibody; SRGAP 1 antibody; srGAP1 antibody; SRGP1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SRGAP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
  • 基因功能參考文獻(xiàn)：
    1. Results show that the protein expression of srGAP1 is remarkably decreased in 47.5% of colorectal cancer (CRC) tissues compared and is found to be associated with tumor progression and poor prognosis. PMID: 27923383
    2. we identified a consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P(meta) = 1.14 x 10(-7)) PMID: 25134534
    3. Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract PMID: 26026792
    4. The elevated miR-145 present in invasive glioblastoma cells (IM3 cells) targets and down-regulated srGAP1, thereby allowing downstream G-proteins to remain in their active state and promote the observed invasive phenotype PMID: 26026080
    5. The interaction of betaPix with srGAP1 is critical for maintaining suppressive crosstalk between Cdc42 and RhoA during 3D collagen migration. PMID: 25150978
    6. Data indicate that srGAP1 possesses a GAP activity specific to Rac1 and is recruited to lamellipodia in a Rac1-dependent manner. PMID: 24006490
    7. genome-wide linkage analysis in populations in Ohio and Poland: Data suggest that missense mutations in SRGAP1 are associated with genetic predisposition to papillary thyroid carcinoma. PMID: 23539728
    8. This study proposed that the expression of SRGAP1 in the anterior neocortex may mark the early location of the human motor cortex, including its corticospinal projection neurons, allowing further study of their early differentiation. PMID: 21060114
    9. FNBP2, ARHGAP13, ARHGAP14 and ARHGAP4 constitute the FNBP2 family characterized by FCH, RhoGAP and SH3 domains. PMID: 12736724

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Thyroid cancer, non-medullary, 2 (NMTC2)
  • 組織特異性：
    Expressed in brain, lung, kidney, and testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17382

    OMIM: 188470

    KEGG: hsa:57522

    STRING: 9606.ENSP00000347198

    UniGene: Hs.210751



主站蜘蛛池模板： 国产亚洲情侣一区二区无| 国产在线视频www色| 精品一区二区三区在线成人| 国产绳艺sm调教室论坛| 午夜尤物禁止18点击进入| 99爱在线精品视频免费观看| 亚洲精品成av人片天堂无码| 国产999精品久久久久久| 中年人妻丰满av无码久久不卡| 亚洲性色av性色在线观看| 一本热久久sm色国产| 欧美性xxxxx极品娇小| 国产精品99久久精品| 国产午精品午夜福利757视频播放| 亚洲午夜精品久久久久久浪潮 | 国产成人艳妇aa视频在线| 麻豆国产尤物av尤物在线观看| 亚洲日本中文字幕乱码在线 | 18无码粉嫩小泬无套在线观看 | 天堂中文在线www天堂在线| 躁躁躁日日躁| 182tv午夜福利在线地址二| 国产a v高清一区二区三区| 亚洲日韩精品无码专区| 国产激情综合五月久久| 国产成人精品午夜视频| 日本高清视频wwww色| 窝窝午夜精品一区二区| 免费人成视频在线观看播放网站| 亚洲男人的天堂一区二区| 亚洲熟妇无码一区二区三区| 日本丰满少妇xxxx| 人妻无码vs中文字幕久久av爆| 婷婷综合久久中文字幕| 窝窝影院午夜看片| 日本毛茸茸的丰满熟妇| 99精品国产福久久久久久| 99久久久国产精品免费蜜臀| 国产黄在线观看免费观看不卡| 动漫精品视频一区二区三区| 任你躁x7x7x7x7在线观看|