在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SOSTDC1 Antibody

SOSTDC1 Antibody

  • 中文名稱：
    SOSTDC1兔多克隆抗體
  • 貨號：
    CSB-PA022416EA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SOSTDC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CDA019 antibody; DKFZp564D206 antibody; Ectodermal BMP inhibitor antibody; Ectodin antibody; sclerostin domain containing 1 antibody; Sclerostin domain containing protein 1 antibody; Sclerostin domain-containing protein 1 antibody; SOSD1_HUMAN antibody; Sostdc1 antibody; USAG-1 antibody; USAG1 antibody; Uterine sensitization associated gene 1 protein antibody; Uterine sensitization-associated gene 1 protein antibody; Wise antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Sclerostin domain-containing protein 1 protein (24-206AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，SOSTDC1 Antibody (CSB-PA022416EA01HU)，的標(biāo)記方式是Non-conjugated。對于SOSTDC1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA022416EB01HU SOSTDC1 Antibody, HRP conjugated ELISA
    FITC CSB-PA022416EC01HU SOSTDC1 Antibody, FITC conjugated
    Biotin CSB-PA022416ED01HU SOSTDC1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
  • 基因功能參考文獻(xiàn)：
    1. findings provide insight into the role of SOSTDC1 as a novel functional tumor suppressor in follicular thyroid cancer through modulating the activities of PI3K/Akt and MAPK/Erk signaling pathways. PMID: 28551845
    2. Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 and cyclin E2. PMID: 26378658
    3. Results conclude that the transcriptional repressor E4BP4 plays a role in repressing epigenetically regulated SOSTDC1 expression in breast cancer cells, which can be reverted by E4BP4 silencing. PMID: 25338303
    4. Epigenetic silencing of SOSTDC1 through methylation is increased in prostate cancer and is associated with accelerated disease progression in patients with prostate cancer PMID: 25858146
    5. Unliganded VDR upregulates the expression of hairless, the gene product of which acts as a downstream comodulator to feedback-repress DKKL1 and SOSTDC1. PMID: 24190897
    6. DNA methylation is involved in the down-regulation of SOSTDC1 expression in gastric cancer. PMID: 23830730
    7. SOSTDC1 is expressed in normal breast tissue and this expression is reduced in breast cancer. PMID: 21113658
    8. Results indicate for the first time that the genetic polymorphisms in SOSTDC1 have an effect on attainment and maintenance of peak bone mass in Chinese women. PMID: 21221677
    9. genetic aberrations near SOSTDC1 are not uncommon in renal cancer, and occur in adult as well as pediatric renal tumors. PMID: 21080955
    10. Data suggest that ectodin is a novel bone morphogenetic protein (BMP) inhibitor which integrates BMP signaling with the SHH and FGF signal pathways PMID: 14623234
    11. USAG1 is expressed in the kidney and functions as a bone morphogenetic protein antagonist. PMID: 15020244
    12. This screen identified a bone morphogenetic protein (BMP) antagonist, SOSTDC1 (sclerostin domain-containing-1) as down-regulated in kidney tumors. PMID: 18032587
    13. Loss of SOSTDC1 gene is associated with Wilms tumor. PMID: 19760604

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Sclerostin family
  • 組織特異性：
    Highly expressed in kidney and weakly in lung.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21748

    OMIM: 609675

    KEGG: hsa:25928

    STRING: 9606.ENSP00000304930

    UniGene: Hs.648106



主站蜘蛛池模板： 国产一卡2卡3卡四卡精品国色无边| 无遮无挡三级动态图| 国内精品国产三级国产av| 亚洲va中文字幕无码久久| 欧美成人精品 一区二区三区| 18禁真人抽搐一进一出免费| 亚洲性猛交xxxx| 精品高潮呻吟99av无码视频| 人妻少妇久久中文字幕456| 亚洲人成人一区二区三区| 国产又黄又爽胸又大免费视频| 国产a在亚洲线播放| 亚洲国产成人综合一区二区三区 | 亚洲精品无码久久久久秋霞| 中字乱码视频| 国内精品伊人久久久久777| 无码专区—va亚洲v天堂麻豆| 老男人久久青草av高清| 国内精品久久久久久tv| 无码av免费毛片一区二区| 精品国产一区二区三区久久狼 | 中文字幕av无码不卡免费| 2019午夜福利不卡片在线| 日出水了特别黄的视频| 99j久久精品久久久久久| 无码专区亚洲制服丝袜| 国产精品久久久久影院老司| 国产又色又爽无遮挡免费动态图 | 越猛烈欧美xx00动态图| 又色又爽又黄又无遮挡的网站 | 久久久久国产精品人妻aⅴ牛牛| 国产成人无码a区在线观看视频免费 | 成人乱码一区二区三区av| 人人妻人人澡人人爽人人精品浪潮 | 好紧好爽好深再快点av在线| 日本亚洲色大成网站www久久| 亚洲中文字幕无码专区| 亚洲精品久久国产精品浴池| 久久久久高潮毛片免费全部播放 | 国产八十老太另类| 激情内射亚洲一区二区三区|