在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SORCS1 Antibody

SORCS1 Antibody

  • 中文名稱：
    SORCS1兔多克隆抗體
  • 貨號：
    CSB-PA848843LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate
      All lanes: SORCS1 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 130, 134, 132 kDa
      Observed band size: 130 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA848843LA01HU at dilution of 1:100
    • Immunofluorescence staining of MCF-7 cells with CSB-PA848843LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SORCS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SORCS1
  • 別名：
    SORCS1 antibody; SORCS antibody; VPS10 domain-containing receptor SorCS1 antibody; hSorCS antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human VPS10 domain-containing receptor SorCS1 protein (34-175AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SORCS1 Antibody (CSB-PA848843LA01HU)，的標記方式是Non-conjugated。對于SORCS1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA848843LB01HU SORCS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA848843LC01HU SORCS1 Antibody, FITC conjugated
    Biotin CSB-PA848843LD01HU SORCS1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. We report for the first time the relevance of SORCS1 polymorphisms for glycemic control and glucose stimulated insulin secretion in obese women with polycystic ovary syndrome. SORCS1 rs1416406 significantly influenced stimulated glucose plasma levels and increased glucose stimulated insulin secretion PMID: 27052493
    2. Data identified associations between single nucleotide polymorphisms in SORCS1 and renal function in large cohorts of European and African ancestry. PMID: 23780848
    3. The propeptide region of sorCS1 contains two separate sites for binding to sortilin. One of these sites is removed from human sorCS1 during processing. PMID: 24128306
    4. Genetic variation of the rs10884402 and rs950809 in intron 1 of SORCS1 is associated with late onset Alzheimer disease in the Chinese Han population. PMID: 23700427
    5. The genetic link between AD[Alzheimer's disease]and SORCS1 gene variations are influenced by ethnic background, sex and whether an individual has type 2 diabetes mellitus PMID: 23279143
    6. [review] Emerging data from a rapidly growing area of research implicates the Vps10 family of receptors and the retromer in physiological intracellular trafficking by neurotrophins and pathogenesis of neurodegeneration. PMID: 23055476
    7. Our data suggested that SORCS1 was in interaction with APOE in the development of late-onset Alzheimer's disease in a Northern Han Chinese population PMID: 22353753
    8. suggest that genetic variation in SORCS1 is associated with memory performance PMID: 22046233
    9. Dysfunction of SorCS1 may contribute to both the amyloid precursor protein/amyloidbeta disturbance underlying Alzheimer disease and the insulin/glucose disturbance underlying diabetes mellitus. PMID: 20881129
    10. SNP which is nearest to SORCS1 is highly significantly associated with glycemic control in individuals with type 1 diabetes PMID: 19875614
    11. human sorCS1 has three isoforms, sorCS1a-c, with completely different cytoplasmic tails and differential expression in tissues PMID: 12482870
    12. Different motifs regulate trafficking of SorCS1 isoforms. PMID: 18315530
    13. SORCS1 SNPs show genotypic association with Alzheimer disease. PMID: 19241460

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    VPS10-related sortilin family, SORCS subfamily
  • 組織特異性：
    Detected in fetal and infant brain and in fetal retina.
  • 數據庫鏈接：

    HGNC: 16697

    OMIM: 606283

    KEGG: hsa:114815

    STRING: 9606.ENSP00000345964

    UniGene: Hs.591915



主站蜘蛛池模板： 国内精品伊人久久久久妇 | 国产成人小视频| 国产精品人妻久久毛片| 国产 日韩 欧美 视频 制服| 7777久久久国产精品消防器材| 狠狠人妻久久久久久综合蜜桃| 236宅宅理论片免费| 男女又色又爽又爽视频| 国产美女口爆吞精普通话| 亚洲成aⅴ人片在线观| 国产成人拍精品视频午夜网站 | 琪琪女色窝窝777777| 爽爽午夜影视窝窝看片| 精品一区国产vr| 国产欧美日韩综合精品一区二区| 国精品人妻无码一区二区三区喝尿| 欧美性欧美巨大黑白大战| 日本高清在线天码一区播放| a三级三级成人网站在线视频| 影视先锋av资源噜噜| 亚洲欧美日韩久久精品| 少妇扒开双腿让我看个够| 国产在线精品一区在线观看| 国产精品人妻一码二码尿失禁| 日日摸天天碰中文字幕你懂的| 一区二区三区鲁丝不卡麻豆| 国产日产精品一区二区三区四区的特点 | 精品人妻少妇一区二区三区| 精品www日韩熟女人妻| 精品国产av最大网站| 亚洲人成人影院在线观看| 毛片无码一区二区三区a片视频| 俄罗斯大荫蒂女人毛茸茸| 日本久久夜夜一本婷婷| 亚洲午夜精品久久久久久浪潮| 肥老熟妇伦子伦456视频| 欧美精品欧美人与动人物牲交| 精品国内自产拍在线观看| gv天堂gv无码男同在线观看| 国产精品自在欧美一区| 久草热8精品视频在线观看|