在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SORCS1 Antibody

SORCS1 Antibody

  • 中文名稱：
    SORCS1兔多克隆抗體
  • 貨號：
    CSB-PA848843LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate
      All lanes: SORCS1 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 130, 134, 132 kDa
      Observed band size: 130 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA848843LA01HU at dilution of 1:100
    • Immunofluorescence staining of MCF-7 cells with CSB-PA848843LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SORCS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SORCS1
  • 別名：
    SORCS1 antibody; SORCS antibody; VPS10 domain-containing receptor SorCS1 antibody; hSorCS antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human VPS10 domain-containing receptor SorCS1 protein (34-175AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SORCS1 Antibody (CSB-PA848843LA01HU)，的標記方式是Non-conjugated。對于SORCS1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA848843LB01HU SORCS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA848843LC01HU SORCS1 Antibody, FITC conjugated
    Biotin CSB-PA848843LD01HU SORCS1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. We report for the first time the relevance of SORCS1 polymorphisms for glycemic control and glucose stimulated insulin secretion in obese women with polycystic ovary syndrome. SORCS1 rs1416406 significantly influenced stimulated glucose plasma levels and increased glucose stimulated insulin secretion PMID: 27052493
    2. Data identified associations between single nucleotide polymorphisms in SORCS1 and renal function in large cohorts of European and African ancestry. PMID: 23780848
    3. The propeptide region of sorCS1 contains two separate sites for binding to sortilin. One of these sites is removed from human sorCS1 during processing. PMID: 24128306
    4. Genetic variation of the rs10884402 and rs950809 in intron 1 of SORCS1 is associated with late onset Alzheimer disease in the Chinese Han population. PMID: 23700427
    5. The genetic link between AD[Alzheimer's disease]and SORCS1 gene variations are influenced by ethnic background, sex and whether an individual has type 2 diabetes mellitus PMID: 23279143
    6. [review] Emerging data from a rapidly growing area of research implicates the Vps10 family of receptors and the retromer in physiological intracellular trafficking by neurotrophins and pathogenesis of neurodegeneration. PMID: 23055476
    7. Our data suggested that SORCS1 was in interaction with APOE in the development of late-onset Alzheimer's disease in a Northern Han Chinese population PMID: 22353753
    8. suggest that genetic variation in SORCS1 is associated with memory performance PMID: 22046233
    9. Dysfunction of SorCS1 may contribute to both the amyloid precursor protein/amyloidbeta disturbance underlying Alzheimer disease and the insulin/glucose disturbance underlying diabetes mellitus. PMID: 20881129
    10. SNP which is nearest to SORCS1 is highly significantly associated with glycemic control in individuals with type 1 diabetes PMID: 19875614
    11. human sorCS1 has three isoforms, sorCS1a-c, with completely different cytoplasmic tails and differential expression in tissues PMID: 12482870
    12. Different motifs regulate trafficking of SorCS1 isoforms. PMID: 18315530
    13. SORCS1 SNPs show genotypic association with Alzheimer disease. PMID: 19241460

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    VPS10-related sortilin family, SORCS subfamily
  • 組織特異性：
    Detected in fetal and infant brain and in fetal retina.
  • 數據庫鏈接：

    HGNC: 16697

    OMIM: 606283

    KEGG: hsa:114815

    STRING: 9606.ENSP00000345964

    UniGene: Hs.591915



主站蜘蛛池模板： 黑人糟蹋人妻hd中文字幕| 奶头又大又白喷奶水av| 成熟人妻av无码专区| 夜夜爽夜夜叫夜夜高潮漏水 | 乱女伦露脸对白在线播放| 久久久久久人妻一区精品| 毛片免费观看天天干天天爽| 国产拍揄自揄精品视频| 无码专区一va亚洲v专区在线| 熟女少妇在线视频播放| 国产精品特黄aaaa片在线观看| 老子影院无码午夜伦不卡| 亚洲成a人片在线观看www| 国产无遮挡a片无码免费| 亚洲欧美成人久久一区| 国产亚洲精品久久yy50| 女人18毛片水真多| 亚洲中文字幕乱码av波多ji| 亚洲欧美中文高清在线专区| 国产免费拔擦拔擦8x高清在线人| 337p粉嫩日本欧洲亚洲大胆| 波多野结衣爽到高潮大喷| 麻豆精品久久久久久中文字幕无码 | 婷婷久久综合九色综合| 中文字幕乱码久久午夜不卡| 又粗又长又硬义又黄又爽| 性xxxx搡xxxxx搡欧美| 真人做受试看120分钟小视频| 18禁真人抽搐一进一出免费| 麻豆av一区二区三区| 国产精品不卡无码av在线播放| 亚洲性色成人av| 欧美人与性动交α欧美精品| 欧美乱妇狂野欧美在线视频| 成人片无码免费播放| 国产日产欧产精品品不卡| 精品少妇人妻av一区二区| 久久亚洲精品无码爱剪辑| 2020精品国产a不卡片| 奇米影视888欧美在线观看| 无码av免费一区二区三区a片|