在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SORCS1 Antibody, Biotin conjugated

  • 中文名稱:
    SORCS1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA848843LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SORCS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SORCS1
  • 別名:
    SORCS1 antibody; SORCS antibody; VPS10 domain-containing receptor SorCS1 antibody; hSorCS antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human VPS10 domain-containing receptor SorCS1 protein (34-175AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. We report for the first time the relevance of SORCS1 polymorphisms for glycemic control and glucose stimulated insulin secretion in obese women with polycystic ovary syndrome. SORCS1 rs1416406 significantly influenced stimulated glucose plasma levels and increased glucose stimulated insulin secretion PMID: 27052493
    2. Data identified associations between single nucleotide polymorphisms in SORCS1 and renal function in large cohorts of European and African ancestry. PMID: 23780848
    3. The propeptide region of sorCS1 contains two separate sites for binding to sortilin. One of these sites is removed from human sorCS1 during processing. PMID: 24128306
    4. Genetic variation of the rs10884402 and rs950809 in intron 1 of SORCS1 is associated with late onset Alzheimer disease in the Chinese Han population. PMID: 23700427
    5. The genetic link between AD[Alzheimer's disease]and SORCS1 gene variations are influenced by ethnic background, sex and whether an individual has type 2 diabetes mellitus PMID: 23279143
    6. [review] Emerging data from a rapidly growing area of research implicates the Vps10 family of receptors and the retromer in physiological intracellular trafficking by neurotrophins and pathogenesis of neurodegeneration. PMID: 23055476
    7. Our data suggested that SORCS1 was in interaction with APOE in the development of late-onset Alzheimer's disease in a Northern Han Chinese population PMID: 22353753
    8. suggest that genetic variation in SORCS1 is associated with memory performance PMID: 22046233
    9. Dysfunction of SorCS1 may contribute to both the amyloid precursor protein/amyloidbeta disturbance underlying Alzheimer disease and the insulin/glucose disturbance underlying diabetes mellitus. PMID: 20881129
    10. SNP which is nearest to SORCS1 is highly significantly associated with glycemic control in individuals with type 1 diabetes PMID: 19875614
    11. human sorCS1 has three isoforms, sorCS1a-c, with completely different cytoplasmic tails and differential expression in tissues PMID: 12482870
    12. Different motifs regulate trafficking of SorCS1 isoforms. PMID: 18315530
    13. SORCS1 SNPs show genotypic association with Alzheimer disease. PMID: 19241460

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    VPS10-related sortilin family, SORCS subfamily
  • 組織特異性:
    Detected in fetal and infant brain and in fetal retina.
  • 數據庫鏈接:

    HGNC: 16697

    OMIM: 606283

    KEGG: hsa:114815

    STRING: 9606.ENSP00000345964

    UniGene: Hs.591915



主站蜘蛛池模板: 欧美亅性猛交内射| 国产日韩在线时看高清视频| 久久久久se色偷偷亚洲精品av| 久久熟妇人妻午夜寂寞影院| 久久久99精品成人片| 国内精品一区二区三区| 国产成人三级一区二区在线观看一| 久久影视久久午夜| 亚洲综合无码一区二区三区不卡| 亚洲国产a∨无码中文777| 人人澡人人透人人爽| 亚洲人成网站在线播放小说| 男女性爽大片视频免费看| 亚洲一区av无码专区在线观看| 女人爽到高潮免费视频大全| 免费人成视频网站在线观看18| 香蕉在线依人视频| 337p日本欧洲亚洲大胆裸体艺术 | 无码免费一区二区三区免费播放| 日韩人妻无码一区二区三区综合| 五 月 丁 香 综合中文| 人妻熟女一区| 国产后进白嫩翘臀在线播放| 国产亚洲精品电影网站在线观看| 国产精品久久久久久2021| 国产在线观看码高清视频| 免费国产乱理伦片在线观看| 亚洲日韩色欲色欲com| 99精品国产免费观看视频| 久久免费午夜福利院| 夜夜高潮夜夜爽高清视频| 97人妻天天摸天天爽天天| 水蜜桃av无码| 少妇精品偷拍高潮少妇小说| 无码人妻h动漫| 特黄特色的大片观看免费视频| 97视频热人人精品免费| 欧美亚洲日本高清不卡| 国产精品久久无码一区二区三区网 | 国产freexxxx性播放麻豆| 精品无人乱码一区二区三区的特点|