在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SORCS1 Antibody, Biotin conjugated

  • 中文名稱:
    SORCS1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA848843LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SORCS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SORCS1
  • 別名:
    SORCS1 antibody; SORCS antibody; VPS10 domain-containing receptor SorCS1 antibody; hSorCS antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human VPS10 domain-containing receptor SorCS1 protein (34-175AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. We report for the first time the relevance of SORCS1 polymorphisms for glycemic control and glucose stimulated insulin secretion in obese women with polycystic ovary syndrome. SORCS1 rs1416406 significantly influenced stimulated glucose plasma levels and increased glucose stimulated insulin secretion PMID: 27052493
    2. Data identified associations between single nucleotide polymorphisms in SORCS1 and renal function in large cohorts of European and African ancestry. PMID: 23780848
    3. The propeptide region of sorCS1 contains two separate sites for binding to sortilin. One of these sites is removed from human sorCS1 during processing. PMID: 24128306
    4. Genetic variation of the rs10884402 and rs950809 in intron 1 of SORCS1 is associated with late onset Alzheimer disease in the Chinese Han population. PMID: 23700427
    5. The genetic link between AD[Alzheimer's disease]and SORCS1 gene variations are influenced by ethnic background, sex and whether an individual has type 2 diabetes mellitus PMID: 23279143
    6. [review] Emerging data from a rapidly growing area of research implicates the Vps10 family of receptors and the retromer in physiological intracellular trafficking by neurotrophins and pathogenesis of neurodegeneration. PMID: 23055476
    7. Our data suggested that SORCS1 was in interaction with APOE in the development of late-onset Alzheimer's disease in a Northern Han Chinese population PMID: 22353753
    8. suggest that genetic variation in SORCS1 is associated with memory performance PMID: 22046233
    9. Dysfunction of SorCS1 may contribute to both the amyloid precursor protein/amyloidbeta disturbance underlying Alzheimer disease and the insulin/glucose disturbance underlying diabetes mellitus. PMID: 20881129
    10. SNP which is nearest to SORCS1 is highly significantly associated with glycemic control in individuals with type 1 diabetes PMID: 19875614
    11. human sorCS1 has three isoforms, sorCS1a-c, with completely different cytoplasmic tails and differential expression in tissues PMID: 12482870
    12. Different motifs regulate trafficking of SorCS1 isoforms. PMID: 18315530
    13. SORCS1 SNPs show genotypic association with Alzheimer disease. PMID: 19241460

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    VPS10-related sortilin family, SORCS subfamily
  • 組織特異性:
    Detected in fetal and infant brain and in fetal retina.
  • 數據庫鏈接:

    HGNC: 16697

    OMIM: 606283

    KEGG: hsa:114815

    STRING: 9606.ENSP00000345964

    UniGene: Hs.591915



主站蜘蛛池模板: 欧美成妇人吹潮在线播放| 国产av无码专区亚洲awww| 亚洲人成网站18禁止人| 日本真人边吃奶边做爽动态图 | 国产成人不卡无码免费视频| 狠狠躁天天躁中文字幕| 夜夜夜高潮夜夜爽夜夜爰爰| 精品无人区码一码二码三码区别| 日韩在线 | 中文| 国产一区二区三区美女| 成熟丰满熟妇高潮xxxxx视频| 小荡货奶真大水多好紧视频| 亚洲人成色77777在线观看大战| 国产美女牲交视频| 青娱乐极品视觉盛宴av| 强伦姧人妻免费无码电影| 少妇的丰满人妻hd高清| 久久久无码一区二区三区| 阳茎伸入女人阳道视频| 麻豆国产成人av在线播放欲色 | 日日躁夜夜躁狠狠躁超碰97| 中文午夜乱理片无码| 岛国在线无码高清视频| 男女性高爱潮免费网站| 无码国产乱人伦偷精品视频| 丰满多毛的陰户视频| 婷婷伊人五月尤物| 永久免费的av在线电影网无码| 国产真实野战在线视频| 亚洲a∨精品一区二区三区| 精品国产乱码久久久久久婷婷| 国产互换人妻hd| 欧美 在线 成 人怡红院| 在线视频观看免费视频18| 熟女少妇内射日韩亚洲| 国产精品一国产精品一k频道| 亚洲伊人久久精品影院| 无码区国产区在线播放| 尤物av无码国产在线看| 女人被爽到高潮视频免费国产 | 天天狠天天天天透在线|