在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SNX17 Antibody, FITC conjugated

  • 中文名稱:
    SNX17兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA614877LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SNX17 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SNX17
  • 別名:
    Similar to a putative C elegans gene encoded in cosmid F17H10 antibody; Snx17 antibody; SNX17_HUMAN antibody; Sorting nexin 17 antibody; Sorting nexin-17 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Sorting nexin-17 protein (280-457AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
  • 基因功能參考文獻:
    1. HPV-16 L2 recruitment of SNX17 occurs prior to capsid disassembly. PMID: 28475030
    2. The double knockdown of SNX17 and SNX27 results in a striking reduction of papillomavirus 16 infection due to interruption of their binding to the L2 viral protein. PMID: 26202251
    3. SNX17 plays a role in the maintenance of normal surface levels of activating receptors and integrins to permit optimum T cell activation at the immune synapse. PMID: 25825439
    4. Data indicate that the major binding site for binding of sorting nexin 17 (SNX17) is confined to the NPXF2 motif in cytoplasmic adaptor protein Krev interaction trapped 1 (KRIT1). PMID: 25059659
    5. Sorting nexin 17 regulates ApoER2 recycling and reelin signaling. PMID: 24705369
    6. The authors demonstrate that SNX17 is essential for infection with all papillomavirus types analyzed, indicating an evolutionarily highly conserved virus entry mechanism. PMID: 23115288
    7. depletion of SNX17 in HeLa cells resulted in lysosomal degradation of multiple members of the integrin family of extracellular matrix recep-tors. PMID: 22492727
    8. expression level of SNX17 may regulate the lysosomal degradation, at least for P-selectin, by suppressing its entry into the inner vesicles of the multi-vesicular bodies (MVBs) PMID: 15769472
    9. Snx 17 binds to a motif in the low-density lipoprotein (LDL) receptor-related protein (LRP) tail distinct from the endocytosis signals and promotes LRP sorting to the recycling pathway in the early endosomes. PMID: 16052210
    10. SNX17 has a role in the indicated KRIT1 function in cell adhesion processes by integrin signaling PMID: 16712798
    11. SNX17 regulates amyloid precursor protein trafficking and processing in the early endosomes PMID: 18276590

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Sorting nexin family
  • 數據庫鏈接:

    HGNC: 14979

    OMIM: 605963

    KEGG: hsa:9784

    STRING: 9606.ENSP00000233575

    UniGene: Hs.278569



主站蜘蛛池模板: 女人夜夜春高潮爽a∨片传媒 | 亚洲成av人片在线观看www| 欧美v国产v亚洲v日韩九九| 亚洲国产成在人网站天堂| 无码精品a∨在线观看十八禁| 已婚少妇美妙人妻系列| 亚洲精品一区久久久久久| 色翁荡熄又大又硬又粗又视频图片| 3p人妻少妇对白精彩视频| av网站的免费观看| 日韩精品成人av在线观看| 久久99精品国产麻豆宅宅| 宅男666在线永久免费观看| 国产xxx视频在线观看软件| 伊人久久精品无码二区麻豆| 久久久久久免费毛片精品| 2018年亚洲欧美在线v| 亚洲精品无码不卡av| 色婷婷综合久久久久中文| 自愉自愉产区二十四区| 爽爽午夜影视窝窝看片| 国产欧美亚洲日韩图片| 亚洲欧美另类久久久精品| 久久久精品久久久久久96| 成在线人免费视频播放| 中文字幕人妻无码系列第三区| 中文字幕无码不卡免费视频| 无码中字出轨中文人妻中文中| 人妻丰满熟妇ⅴ无码区a片| 久久久久久自慰出白浆| 亚洲人成无码网www电影榴莲| 大伊香蕉精品一区二区| 亚洲日韩欧美国产高清αv| 色悠久久久久综合网香蕉| 亚洲最大无码av网站观看| 一二三四区无产乱码1000集| 边啃奶头边躁狠狠躁| 久久人人爽av亚洲精品| 欧美精品在线观看| 性夜夜春夜夜爽aa片a| 久久精品国产男包|