在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SNX10 Antibody, FITC conjugated

  • 中文名稱:
    SNX10兔多克隆抗體, FITC偶聯(lián)
  • 貨號:
    CSB-PA896538LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SNX10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SNX10
  • 別名:
    2410004M09Rik antibody; MGC109202 antibody; MGC33054 antibody; OPTB8 antibody; SNX10 antibody; SNX10_HUMAN antibody; Sorting nexin 10 antibody; Sorting nexin-10 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Sorting nexin-10 protein (124-201AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption.
  • 基因功能參考文獻(xiàn):
    1. supplementation with calcium gluconate rescued mice from the rachitic phenotype and extended life span in global Snx10-deficient mice, suggesting that this may be a life-saving component of the clinical approach to Snx10-dependent human osteopetrosis PMID: 25811986
    2. Data suggest Tyr32 and Arg51 in SNX10 are important for protein stability and play critical roles in vacuolation in osteoclasts; mutation Arg16Leu (seen in autosomal recessive osteopetrosis patients) affects protein-protein interactions of SNX10. PMID: 25212774
    3. results confirm the involvement of the SNX10 gene in human ARO and identify a new subset with a relatively favorable prognosis as compared to TCIRG1-dependent cases PMID: 23280965
    4. Structure of sorting nexin 11 (SNX11) reveals a novel extended phox homology (PX) domain critical for inhibition of SNX10-induced vacuolation. PMID: 23615901
    5. Since inhibition of vesicular trafficking is essential for osteoclast formation and activity and SNX10 is involved in vesicular trafficking, these studies may identify a new gene involved in the development of bone diseases including osteoporosis. PMID: 22174188
    6. Identification of SNX10 as a new osteopetrosis associated gene in consanguineous families of Palestinian origin. PMID: 22499339
    7. SNX10 regulates the ciliary trafficking of Rab8a, which is a critical regulator of ciliary membrane extension. PMID: 21844891
    8. SNX10 activity may be involved in the regulation of endosome homeostasis PMID: 17012226

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Osteopetrosis, autosomal recessive 8 (OPTB8)
  • 亞細(xì)胞定位:
    Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=May also localize to nucleus and endoplasmic reticulum.
  • 蛋白家族:
    Sorting nexin family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14974

    OMIM: 614780

    KEGG: hsa:29887

    STRING: 9606.ENSP00000343709

    UniGene: Hs.741316



主站蜘蛛池模板: 中文字幕人成乱码在线观看| 中文字幕人妻被公上司喝醉在线| 高清无码午夜福利视频| 久久婷婷五月综合色国产香蕉| 呻吟国产av久久一区二区| 久久青青草原国产精品最新片 | 无码抽搐高潮喷水流白浆| 五十路熟女一区二区三区| 美女脱了内裤张开腿让男人桶网站 | 黑人巨大精品欧美黑寡妇| 国产免费无码一区二区视频| 亚洲 欧美 另类 制服 日韩| 日韩精品无码人成视频| 久久精品国产99国产精2021| 亚洲精品一区二区久久| 欧美性大战久久久久久久| 97久章草在线视频播放| 亚洲精品专区成人网站| 美女扒开大腿让男人桶| 国产精品久久久久久影视| 亚洲欲色欲色xxxxx在线观看| 国产成人精品a视频免费福利| 欧美伊人久久大香线蕉综合| 亚洲国产精品国自产拍av| 免费看美女部位隐私网站| 亚洲伊人久久精品酒店| 国产成人无码一二三区视频| 亚洲第一女人av| 国产精品成人久久电影| 欧美综合自拍亚洲综合区| 人人添人人澡人人澡人人人人| 亚洲日韩精品一区二区三区| 色综合久久中文娱乐网| 曰本一道本久久88不卡| 自拍偷在线精品自拍偷免费| 亚洲日韩av在线观看| 真人性生交免费视频| 小12萝裸体自慰出白浆| 久久久久av无码免费网| 欧美性生 活18~19| 黄网站色视频免费国产|