在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SNRPA Antibody

  • 中文名稱:
    SNRPA兔多克隆抗體
  • 貨號:
    CSB-PA022327GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SNRPA
  • 別名:
    fc19d01 antibody; Mud1 antibody; small nuclear ribonucleoprotein polypeptide A antibody; snRNP A antibody; snRNP protein A antibody; SNRPA antibody; SNRPA_HUMAN antibody; U1 small nuclear ribonucleoprotein A antibody; U1 small nuclear RNP specific A antibody; U1 snRNP A antibody; U1 snRNP specific protein A antibody; U1-A antibody; U1A antibody; wu:fc19d01 antibody; zgc:77810 antibody
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SNRPA
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
  • 基因功能參考文獻:
    1. SNRPA may contribute to GC progression via NGF and could be a prognostic biomarker for GC. PMID: 30039889
    2. p65 activation triggered by TCR signaling could promote SNRPA transcription and 3' UTR shortening of STAT5B. Thus we propose that the alternative polyadenylation switching of STAT5B induced by TCR activation is mediated by SNRPA. PMID: 28954886
    3. a new mechanism for regulating SMN levels and provides new insight into the roles of U1A in 3' processing of mRNAs. PMID: 24362020
    4. An analysis of the kinetic data suggests three phases of U1A-SL2 RNA complex dissociation with time scales of approximately 100 mus, approximately 50 ms, and approximately 2 s. We propose that the first step of dissociation is a fast rearrangement of the complex to form a loosely bound complex. PMID: 21419778
    5. structural analysis of U1A protein-stem loop 2 RNA recognition PMID: 21384338
    6. study shows that the yellow fever virus (YFV) NS5 protein is able to interact with U1A, a protein involved in splicing and polyadenylation; a region between amino acids 368 and 448 was identified as the site of interaction of the NS5 protein with U1A PMID: 21298455
    7. 13)C NMR relaxation studies of base and ribose dynamics for the RNA internal loop target of human U1A protein located within the 3'-untranslated region (3'-UTR) of the mRNA coding for U1A itself PMID: 15890361
    8. Identification of PSF, p54(nrb), PTB, and U1A as proteins specifically bound to the COX-2 polyadenylation signal upstream sequence elements . PMID: 17507659
    9. Functional U1A site in a cellular gene and of a single gene containing two dissimilar elements that inhibit nuclear polyadenylation. PMID: 17942741

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    RRM U1 A/B'' family
  • 數據庫鏈接:

    HGNC: 11151

    OMIM: 182285

    KEGG: hsa:6626

    STRING: 9606.ENSP00000243563

    UniGene: Hs.466775



主站蜘蛛池模板: 久久久水蜜桃国产成人网站| 精品一区二区三区免费播放| 少妇一夜三次一区二区| 日本不卡三区| 99久久无色码中文字幕人妻蜜柚| 波多野结衣一区二区免费视频| 18禁超污无遮挡无码免费游戏| 激情综合色综合啪啪开心| 中文国产乱码在线人妻一区二区 | 精品人妻无码区在线视频| 啪啪后入内射日韩| 亚洲精品久久久久午夜福利 | 免费视频成人片在线观看| 色欲香天天综合网站| 天堂8在线天堂资源bt| 国产伦理一区二区| 久久婷婷激情综合色综合俺也去 | 黑人巨茎大战俄罗斯美女| 久久亚洲人成综合网| 又硬又粗进去好爽免费| 亚洲欧美综合区自拍另类| 国模无码视频一区| 日本精品中文字幕在线播放| 国产午夜福利不卡在线秋霞秋霞| 黑人巨茎大战白人美女| 久久96国产精品久久久| 日韩a片无码一区二区三区电影| 人妻少妇久久中文字幕| 国产精品久久无码一区二区三区网 | 天天综合网久久综合免费人成| 国产亚洲久久久久久久| 性生交大片免费看女人按摩 | 午夜国人精品av免费看| 亚洲欲色欲香天天综合网| 久久亚洲精精品中文字幕| 伊人久久成综合久久影院| 中国国产1级毛卡片| 毛片免费视频观看| www国产亚洲精品久久网站| 亚洲精品tv久久久久久久久j| 国产精品熟妇一区二区三区四区|