在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLCO1C1 Antibody

SLCO1C1 Antibody

  • 中文名稱：
    SLCO1C1兔多克隆抗體
  • 貨號：
    CSB-PA021744GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLCO1C1
  • 別名：
    OAT-RP-5 antibody; OATP-14 antibody; OATP-F antibody; OATP1 antibody; OATP1C1 antibody; OATPRP5 antibody; Organic anion transporter F antibody; Organic anion transporter polypeptide-related protein 5 antibody; organic anion transporting polypeptide 14 antibody; Organic anion-transporting polypeptide 14 antibody; SLC21A14 antibody; Slco1c1 antibody; SO1C1_HUMAN antibody; solute carrier family 21 (organic anion transporter), member 14 antibody; Solute carrier family 21 member 14 antibody; Solute carrier organic anion transporter family member 1C1 antibody; solute carrier organic anion transporter family, member 1C1 antibody; Thyroxine transporter antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OATP14
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a significant role in regulating T4 flux into and out of the brain.
  • 基因功能參考文獻：
    1. The genetic variant, rs3794271, located within the PDE3A-SLCO1C1 locus was analyzed for correlation with treatment response using both the EULAR classification criteria and absolute change in (Delta)DAS28 scores as outcome measures correlated with anti-TNF response in a large UK rheumatoid arthritis cohort. PMID: 27180831
    2. We found a highly significant association between PDE3A-SLCO1C1 and the clinical response to TNF blockers PMID: 25403996
    3. The PDE3A-SLCO1C1 locus rs3794271 SNP showed a highly significant association with anti-TNF treatment response. PMID: 23651021
    4. Compared with the adult cerebral cortex, mRNAs encoding OATP1A2, OATP1C1, OATP3A1 variant 2, OATP4A1, LAT2 and CD98 were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8, MCT10, OATP3A1 variant 1 and LAT1 were similar. PMID: 21486766
    5. The strong expression of MCT10 and OATP1C1 in the human hypothalamus indicates a possible role in the regulation of the hypothalamus-pituitary-thyroid axis. PMID: 21508134
    6. We have isolated and functionally characterized OATP-F. OATP-F has a more selective substrate preference and may play an important role in the disposition of thyroid hormones in brain and testis. PMID: 12351693
    7. OATP1C1 polymorphisms are associated with fatigue and depression, but do not explain differences in neurocognitive functioning or appreciation of LT4-LT3 combination therapy. PMID: 18410547
    8. OATP1C1 mediates transport of thyroid hormones and increases the access of these substrates to the intracellular active sites of the deiodinases with no effect of genetic variation PMID: 18566113
    9. OATP14 mRNA and protein are strongly enriched in mouse and rat cerebral microvessels but not in human microvessels. PMID: 18687783
    10. Protein is highly expressed in the intestine, kidney, cholangiocytes and the blood-brain barrier. PMID: 19290786
    11. Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18410547

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Organo anion transporter (TC 2.A.60) family
  • 組織特異性：
    Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels.
  • 數據庫鏈接：

    HGNC: 13819

    OMIM: 613389

    KEGG: hsa:53919

    STRING: 9606.ENSP00000370964

    UniGene: Hs.47261



主站蜘蛛池模板： 欧美又粗又大xxxxbbbb疯狂| 无码一区18禁3d| 国语对白做受xxxxx在| 精品国产一区二区av麻豆| 午夜在线观看免费线无码视频| 亚洲一区av无码少妇电影| 国产成人手机高清在线观看网站 | 人妻少妇精品久久| 狂野欧美激情性xxxx| 中文字幕av无码不卡| 国产精品午夜福利不卡120 | 成人免费b2b网站大全在线| 野花在线无码视频在线播放| 女上男下啪啪激烈高潮无遮盖| 日本污ww视频网站| 精品国产乱码久久久久久郑州公司 | 免免费国产aaaaa片| 少妇人妻邻居| а√中文在线资源库| 亚洲精品国产综合麻豆久久99| 亚洲精品无码中文久久字幕| 曰本无码人妻丰满熟妇啪啪| 在线精品一区二区三区| 69成人免费视频无码专区| 伊人色综合九久久天天蜜桃| 亚洲欧美色中文字幕在线| 麻豆av福利av久久av| 亚洲中文无码a∨在线观看| 国产成人美女视频网站| 午夜丰满少妇性开放视频| 国产伦精品一区二区三区免费| 黑人巨茎大战欧美白妇免费| 美女扒开腿让男人桶爽揉| 日本成本人片免费网站| 亚洲人精品午夜射精日韩| 久久精品免视看国产成人 | 夜夜揉揉日日人人| 日本中文字幕有码在线视频| 日产精品高潮呻吟av久久| 国产日韩精品视频无码| 日韩a片无码毛片免费看|