在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLCO1C1 Antibody

SLCO1C1 Antibody

  • 中文名稱：
    SLCO1C1兔多克隆抗體
  • 貨號：
    CSB-PA021744GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLCO1C1
  • 別名：
    OAT-RP-5 antibody; OATP-14 antibody; OATP-F antibody; OATP1 antibody; OATP1C1 antibody; OATPRP5 antibody; Organic anion transporter F antibody; Organic anion transporter polypeptide-related protein 5 antibody; organic anion transporting polypeptide 14 antibody; Organic anion-transporting polypeptide 14 antibody; SLC21A14 antibody; Slco1c1 antibody; SO1C1_HUMAN antibody; solute carrier family 21 (organic anion transporter), member 14 antibody; Solute carrier family 21 member 14 antibody; Solute carrier organic anion transporter family member 1C1 antibody; solute carrier organic anion transporter family, member 1C1 antibody; Thyroxine transporter antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human OATP14
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a significant role in regulating T4 flux into and out of the brain.
  • 基因功能參考文獻：
    1. The genetic variant, rs3794271, located within the PDE3A-SLCO1C1 locus was analyzed for correlation with treatment response using both the EULAR classification criteria and absolute change in (Delta)DAS28 scores as outcome measures correlated with anti-TNF response in a large UK rheumatoid arthritis cohort. PMID: 27180831
    2. We found a highly significant association between PDE3A-SLCO1C1 and the clinical response to TNF blockers PMID: 25403996
    3. The PDE3A-SLCO1C1 locus rs3794271 SNP showed a highly significant association with anti-TNF treatment response. PMID: 23651021
    4. Compared with the adult cerebral cortex, mRNAs encoding OATP1A2, OATP1C1, OATP3A1 variant 2, OATP4A1, LAT2 and CD98 were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8, MCT10, OATP3A1 variant 1 and LAT1 were similar. PMID: 21486766
    5. The strong expression of MCT10 and OATP1C1 in the human hypothalamus indicates a possible role in the regulation of the hypothalamus-pituitary-thyroid axis. PMID: 21508134
    6. We have isolated and functionally characterized OATP-F. OATP-F has a more selective substrate preference and may play an important role in the disposition of thyroid hormones in brain and testis. PMID: 12351693
    7. OATP1C1 polymorphisms are associated with fatigue and depression, but do not explain differences in neurocognitive functioning or appreciation of LT4-LT3 combination therapy. PMID: 18410547
    8. OATP1C1 mediates transport of thyroid hormones and increases the access of these substrates to the intracellular active sites of the deiodinases with no effect of genetic variation PMID: 18566113
    9. OATP14 mRNA and protein are strongly enriched in mouse and rat cerebral microvessels but not in human microvessels. PMID: 18687783
    10. Protein is highly expressed in the intestine, kidney, cholangiocytes and the blood-brain barrier. PMID: 19290786
    11. Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18410547

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Organo anion transporter (TC 2.A.60) family
  • 組織特異性：
    Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels.
  • 數據庫鏈接：

    HGNC: 13819

    OMIM: 613389

    KEGG: hsa:53919

    STRING: 9606.ENSP00000370964

    UniGene: Hs.47261



主站蜘蛛池模板： 特级无码毛片免费视频播放▽| 亚洲一区二区三区四区五区六 | 天天摸夜夜摸夜夜狠狠添| 成 人 网 站 免费观看| 亚洲а∨天堂久久精品2021| 午夜福利在线永久视频| 午夜无码片在线观看影院y| 无码一区二区三区av在线播放| 亚洲亚洲人成综合网络| 国产真实露脸乱子伦原著 | 久久久久99人妻一区二区三区| 中文日产乱幕九区无线码 | 无码任你躁久久久久久| 日本大乳高潮视频在线观看| 国产 高潮 抽搐 正在播放 | av色综合久久天堂av色综合在| 男女车车的车车网站w98免费 | 亚洲欧洲自拍拍偷午夜色| 超碰香蕉人人网99精品| 热の综合热の国产热の潮在线| 精产国品一二三产品蜜桃| 免费无码毛片一区二三区| 亚洲日产av中文字幕无码偷拍| 国产 日韩 另类 视频一区| 曰本无码人妻丰满熟妇啪啪| 99精品久久久久久久婷婷| 亚洲欧洲无码av不卡在线| 国产精品毛片在线完整版sab| 中文字幕人乱码中文字幕| 日产国产精品亚洲系列| 久久久一本精品久久精品六六| 欧美真人性做爰全过程| 香蕉久久一区二区三区啪啪| 啪啪后入内射日韩| 亚洲肥老太bbw中国熟女| 无码免费毛片手机在线无卡顿 | 亚洲鲁丝片一区二区三区| 夜晚被公侵犯的人妻深田字幕| 丰满白嫩人妻中出无码| 18禁网站免费无遮挡无码中文| 十八禁真人啪啪免费网站|