在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC6A6 Antibody

SLC6A6 Antibody

  • 中文名稱：
    SLC6A6兔多克隆抗體
  • 貨號：
    CSB-PA021704LA01HU
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: PC-3 whole cell lysate, HL60 whole cell lysate,Mouse Brain tissue lysate,Mouse Liver tissue lysate
      All lanes: SLC6A6 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 70 kDa
      Observed band size: 70 kDa
    • Immunofluorescent analysis of MCF7 cells using CSB-PA021704LA01HU at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品描述：

    SLC6A6 polyclonal antibody CSB-PA021704LA01HU was produced in the rabbit. The recombinant human sodium- and chloride-dependent taurine transporter protein (1-49aa) is used as the immunogen. The non-conjugated IgG got purified by the antigen affinity method and has high purity.

    This rabbit anti-human SLC6A6 polyclonal antibody only reacts with the SLC6A6 proteins of human origin and may be used to detect the endogenous levels of SLC6A6 protein. It has got quality tested in the ELISA, WB, and IF applications. The users can use this antibody to detect the levels, identify the presence and size, and trace the position of the SLC6A6 protein.

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SLC6A6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    MGC10619 antibody; MGC131729 antibody; OTTHUMP00000208177 antibody; OTTHUMP00000208180 antibody; SC6A6_HUMAN antibody; SLC6A6 antibody; Sodium- and chloride-dependent taurine transporter antibody; Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 antibody; Solute carrier family 6 member 6 antibody; TAUT antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Sodium- and chloride-dependent taurine transporter protein (1-49AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SLC6A6 Antibody (CSB-PA021704LA01HU)，的標記方式是Non-conjugated。對于SLC6A6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA021704LB01HU SLC6A6 Antibody, HRP conjugated ELISA
    FITC CSB-PA021704LC01HU SLC6A6 Antibody, FITC conjugated
    Biotin CSB-PA021704LD01HU SLC6A6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.01% thimerosal，50% glycerol，pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
  • 基因功能參考文獻：
    1. TauT gene expression is significantly upregulated in mononuclear leukocytes of type 1 diabetes patients and is related to HbA1c levels and inversely to plasma homocysteine. PMID: 26955642
    2. CNDP1 and CARNS are expressed in glomeruli and tubular cells; TauT is expressed in renal epithelial cells; CDNP1 may have a role in diabetic neuropathy PMID: 26206726
    3. This is the first study to present information on the transcriptional regulation of taurine transporter gene and the localization of the taurine transporter protein in chondrocytic cells. PMID: 25501278
    4. Neurotransmitter transporters including SLC6A6 and SLC6A13 mediate the uptake of 5-aminolevulinic acid (ALA) and can play roles in the enhancement of ALA-induced accumulation of protoporphyrin in cancerous cells. PMID: 24842606
    5. Immunocytochemistry and flow cytometry analyses revealed that these mAbs recognized the native form of the extracellular domain of SLC6A6 on the cell surface. PMID: 24866236
    6. Taurine transporter is a novel pathological marker for stressed motor neurons in amyotrophic lateral sclerosis. PMID: 23180277
    7. Taurine transporter deficiency results in aberrant trophoblast turnover and fetal growth restriction. PMID: 23519128
    8. Syncytiotrophoblast TauT activity is reduced in maternal obesity and pre-eclampsia compared to normal pregnancy. PMID: 23392873
    9. Knockdown of TauT impairs kidney development, possibly through regulation of cell cycle-related genes. PMID: 23392892
    10. TauT gene is overexpressed in peripheral blood mononuclear cells of type 2 diabetic patients. PMID: 21739148
    11. TNF-alpha-treated cells showed a higher mRNA level of the TAUT (taurine transporter) than did the control cells. PMID: 12062416
    12. TauT is involved with p53 in renal development and apoptosis. PMID: 12163498
    13. regulation by WT1 PMID: 12681485
    14. nitric oxide plays an important role in downregulating microvillous plasma membrane taurine transporter activity in intrauterine growth restriction PMID: 15166008
    15. The increased expression level of TAUT mRNA by hypertonicity was repressed by the specific Ca(2+)/CaM kinase II inhibitor. PMID: 15225620
    16. TAUT activity in TNF-alpha-treated Caco-2 cells suggests that up-regulation was associated with an increase in the amount of TAUT. PMID: 15630186
    17. reporter assay revealed that TNF-alpha-induced TAUT transcriptional activity through the NF-kappaB consensus-like sequence in the human TAUT promoter region PMID: 15907840
    18. taurine cotransporter is regulated by oxidative stress and overexpression of aldose reductase and high glucose impair this response PMID: 16356117
    19. Greater system beta activity in fetal platelets compared with T lymphocytes is the result of relatively greater TAUT mRNA and protein expression. PMID: 16956961
    20. Report taurine transporter activity in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment. PMID: 18703994
    21. This study demonstrates the functional coexpression of TauT along with the PAT1 transporter (SLC36A1) at the apical membrane of the intestinal epithelium. PMID: 19074966
    22. critical role in protecting against cisplatin-induced nephrotoxicity, possibly by attenuating a p53-dependent pathway PMID: 19423693
    23. Glucose reduced taurine transporter (TauT) mRNA and protein in a dose-dependent manner. PMID: 19602579

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A6 subfamily
  • 組織特異性：
    Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
  • 數據庫鏈接：

    HGNC: 11052

    OMIM: 186854

    KEGG: hsa:6533

    STRING: 9606.ENSP00000354107

    UniGene: Hs.529488



主站蜘蛛池模板： 国产一区二区三区在线观看免费| 东北老女人高潮大喊舒服死了| 亚洲中文在线精品国产| 亚洲中文字幕无码中文字| 精品人妻一区二区三区四区| 亚洲精品久久片久久久久| 国产无遮挡a片又黄又爽漫画| 国自产偷精品不卡在线| 国产又粗又猛又大爽老大爷| 欧洲一卡2卡3卡4卡国产| 让少妇爽到高潮视频| 国产一精品一av一免费| 精品视频一区二区三区在线观看 | 丰满爆乳无码一区二区三区| 欧美极p品少妇的xxxxx| 国产欧美国日产高清| 国产美女在线精品免费观看网址| 福利视频在线播放| 国产成+人+综合+亚洲专区| 337p日本欧洲亚洲大胆69影院| 亚洲爆乳大丰满无码专区| 国产免费麻传媒精品国产av| 国产成人免费高清直播| 人妻互换一二三区激情视频| 色五月五月丁香亚洲综合网| 国产午夜精华无码网站| 久久精品伊人一区二区三区| 亚洲精品一区二区久| 国产一卡三卡四卡无卡精品| 东京热大乱系列无码| 成年女人免费碰碰视频| 日日噜噜夜夜狠狠久久丁香五月| 人妻无码少妇一区二区| 真人作爱90分钟免费看视频| 欧洲熟妇牲交| 成人亚洲欧美久久久久| 国产在线精品一区在线观看 | 少妇高潮流白浆在线观看| 午夜嘿嘿嘿在线观看| 毛片免费全部播放无码| 久青草无码视频在线观看|