在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC26A2 Antibody

  • 中文名稱:
    SLC26A2兔多克隆抗體
  • 貨號:
    CSB-PA021525LA01HU
  • 規格:
    ¥440
  • 圖片:
    • IHC image of CSB-PA021525LA01HU diluted at 1:300 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA021525LA01HU diluted at 1:300 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA021525LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC26A2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC26A2
  • 別名:
    SLC26A2 antibody; DTD antibody; DTDST antibody; Sulfate transporter antibody; Diastrophic dysplasia protein antibody; Solute carrier family 26 member 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Sulfate transporter protein (614-739AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,SLC26A2 Antibody (CSB-PA021525LA01HU),的標記方式是Non-conjugated。對于SLC26A2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA021525LB01HU SLC26A2 Antibody, HRP conjugated ELISA
    FITC CSB-PA021525LC01HU SLC26A2 Antibody, FITC conjugated
    Biotin CSB-PA021525LD01HU SLC26A2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Sulfate transporter. May play a role in endochondral bone formation.
  • 基因功能參考文獻:
    1. Two heterozygous mutations in SLC26A2 mutations occur in a three-generational family with cases of multiple epiphyseal dysplasias. PMID: 29024831
    2. Results show that SLC26A2 expression is high in numerous tumor types and, provide evidence that it downregulates the TRAIL receptors, DR4 and DR5 which confers resistance to TRAIL. PMID: 28108622
    3. slc26a2 is to be a critical otic gene whose dysfunction may induce hearing impairment PMID: 26375458
    4. findings provide the first identification of autosomal dominant SLC26A2 mutations in patients with dysplastic spondylolysis, suggesting a new clinical entity in the pathogenesis of chondrodysplasia involving lumbosacral spine PMID: 26077908
    5. Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion. PMID: 24591336
    6. Up-regulation of SLC26A2 is associated with colorectal cancer. PMID: 24222123
    7. A compound heterozygote SLC26A2 mutation is associated with robin sequence, mild limbs shortness, accelerated carpal ossification, and multiple epiphysial dysplasia PMID: 23840040
    8. SLC13A4 and SLC26A2 were the most abundant sulfate transporter mRNAs, which localized to syncytiotrophoblast and cytotrophoblast cells, respectively. PMID: 23453247
    9. 73% of autosomal-recessive multiple epiphyseal dysplasia patients were either homozygous, or compound heterozygous, for SLC26A2 mutations. PMID: 21922596
    10. Solute carrier family 26 member a2 (Slc26a2) protein functions as an electroneutral SOFormula/OH-/Cl- exchanger regulated b PMID: 22190686
    11. Mutations in the SLC26A2 gene causes diastrophic dysplasia. PMID: 21155763
    12. Analysis suggests that, while the DTDST family of disorders contains at least seven different conditions, gene mutations appear to cause a phenotypic continuum. DTDST genotype alone is an imperfect predictor of clinical severity along this continuum. PMID: 21077202
    13. New intermediate phenotype between MED and DD caused by compound heterozygous mutations in the DTDST gene is reported. PMID: 21077204
    14. Characterize transport of oxalate and sulfate by human SLC26A2 and mouse Slc26a2 expressed in Xenopus oocytes. PMID: 20219950
    15. Diminished DTDST expression through epigenetic silencing is associated with colon cancer. PMID: 20460514
    16. DTDST function is crucial for the uptake of extracellular sulfate required for proteoglycan sulfation. PMID: 14692227
    17. The effects of sulfur availablility on proteoglycan sulfation in mice transgenic for a mutation of this gene are reported. PMID: 16719839
    18. This study found an association between single nucleotide polymorphisms of the SLC26A2 gene and juvenile idiopathic arthritis. PMID: 17393463
    19. DTDST is upregulated by dexamethasone stimulation of HT1080 fibrosarcoma cells and is required for fibronectin (FN) extracellular matrix deposition by these cells. PMID: 18056413
    20. A novel SLC26A2 mutation was found in all subjects, inserted by site-directed mutagenesis in a vector harbouring the SLC26A2 cDNA, and expressed in sulfate transport deficient Chinese hamster ovary (CHO) cells to measure sulfate uptake activity PMID: 18708426

    顯示更多

    收起更多

  • 相關疾病:
    Diastrophic dysplasia (DTD); Achondrogenesis 1B (ACG1B); Atelosteogenesis 2 (AO2); Multiple epiphyseal dysplasia 4 (EDM4)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    SLC26A/SulP transporter (TC 2.A.53) family
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 10994

    OMIM: 222600

    KEGG: hsa:1836

    STRING: 9606.ENSP00000286298

    UniGene: Hs.302738



主站蜘蛛池模板: 无码国产偷倩在线播放| 99久久精品无码一区二区三区| 国产精品永久免费视频| 18禁亚洲深夜福利人口| 国产精品a久久777777| 国产全是老熟女太爽了| 在线观看免费人成视频色9| 国产色诱视频在线观看| 四库影院永久国产精品地址 | 久久亚洲国产精品五月天婷| 情侣黄网站免费看| 色8久久人人97超碰香蕉987| 2020年无码国产精品高清免费| 国产亚洲精品影视在线| 真人与拘做受免费视频| 日本日本乱码伦视频在线观看| 国产免费人成网站x8x8| 亚洲精品成av人片天堂无码| 亚洲精品成人无码中文毛片不卡 | 热99re久久精品这里都是精品免费 | 人人妻人人妻人人人人妻人人| 天天av天天翘天天综合网色鬼| 内射毛片内射国产夫妻| 在线播放人成视频观看| 亚洲色素色无码专区| 人妻少妇精品视频二区| 久久/这里只精品热在线获取| 国产精品99久久免费观看| 国产乱人伦精品一区二区在线观看| 国模无码视频一区| 亚洲高清专区日韩精品| 亚洲精品无码ma在线观看| 搡老熟女老女人一区二区| 久艹视频免费看| 国产精品第一区揄拍无码| 18禁止看的免费污网站| 免费又黄又裸乳的视频| 激情综合五月丁香亚洲| 欧美浓毛大泬视频| 色与欲影视天天看综合网| 亚洲在av极品无码|