在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC26A2 Antibody, FITC conjugated

  • 中文名稱:
    SLC26A2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA021525LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC26A2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC26A2
  • 別名:
    SLC26A2 antibody; DTD antibody; DTDST antibody; Sulfate transporter antibody; Diastrophic dysplasia protein antibody; Solute carrier family 26 member 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Sulfate transporter protein (614-739AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Sulfate transporter. May play a role in endochondral bone formation.
  • 基因功能參考文獻:
    1. Two heterozygous mutations in SLC26A2 mutations occur in a three-generational family with cases of multiple epiphyseal dysplasias. PMID: 29024831
    2. Results show that SLC26A2 expression is high in numerous tumor types and, provide evidence that it downregulates the TRAIL receptors, DR4 and DR5 which confers resistance to TRAIL. PMID: 28108622
    3. slc26a2 is to be a critical otic gene whose dysfunction may induce hearing impairment PMID: 26375458
    4. findings provide the first identification of autosomal dominant SLC26A2 mutations in patients with dysplastic spondylolysis, suggesting a new clinical entity in the pathogenesis of chondrodysplasia involving lumbosacral spine PMID: 26077908
    5. Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex and regulates aldosterone secretion. PMID: 24591336
    6. Up-regulation of SLC26A2 is associated with colorectal cancer. PMID: 24222123
    7. A compound heterozygote SLC26A2 mutation is associated with robin sequence, mild limbs shortness, accelerated carpal ossification, and multiple epiphysial dysplasia PMID: 23840040
    8. SLC13A4 and SLC26A2 were the most abundant sulfate transporter mRNAs, which localized to syncytiotrophoblast and cytotrophoblast cells, respectively. PMID: 23453247
    9. 73% of autosomal-recessive multiple epiphyseal dysplasia patients were either homozygous, or compound heterozygous, for SLC26A2 mutations. PMID: 21922596
    10. Solute carrier family 26 member a2 (Slc26a2) protein functions as an electroneutral SOFormula/OH-/Cl- exchanger regulated b PMID: 22190686
    11. Mutations in the SLC26A2 gene causes diastrophic dysplasia. PMID: 21155763
    12. Analysis suggests that, while the DTDST family of disorders contains at least seven different conditions, gene mutations appear to cause a phenotypic continuum. DTDST genotype alone is an imperfect predictor of clinical severity along this continuum. PMID: 21077202
    13. New intermediate phenotype between MED and DD caused by compound heterozygous mutations in the DTDST gene is reported. PMID: 21077204
    14. Characterize transport of oxalate and sulfate by human SLC26A2 and mouse Slc26a2 expressed in Xenopus oocytes. PMID: 20219950
    15. Diminished DTDST expression through epigenetic silencing is associated with colon cancer. PMID: 20460514
    16. DTDST function is crucial for the uptake of extracellular sulfate required for proteoglycan sulfation. PMID: 14692227
    17. The effects of sulfur availablility on proteoglycan sulfation in mice transgenic for a mutation of this gene are reported. PMID: 16719839
    18. This study found an association between single nucleotide polymorphisms of the SLC26A2 gene and juvenile idiopathic arthritis. PMID: 17393463
    19. DTDST is upregulated by dexamethasone stimulation of HT1080 fibrosarcoma cells and is required for fibronectin (FN) extracellular matrix deposition by these cells. PMID: 18056413
    20. A novel SLC26A2 mutation was found in all subjects, inserted by site-directed mutagenesis in a vector harbouring the SLC26A2 cDNA, and expressed in sulfate transport deficient Chinese hamster ovary (CHO) cells to measure sulfate uptake activity PMID: 18708426

    顯示更多

    收起更多

  • 相關疾病:
    Diastrophic dysplasia (DTD); Achondrogenesis 1B (ACG1B); Atelosteogenesis 2 (AO2); Multiple epiphyseal dysplasia 4 (EDM4)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    SLC26A/SulP transporter (TC 2.A.53) family
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 10994

    OMIM: 222600

    KEGG: hsa:1836

    STRING: 9606.ENSP00000286298

    UniGene: Hs.302738



主站蜘蛛池模板: 成人网站免费高清视频在线观看| 色婷婷久久综合中文久久蜜桃av| 成人性生交片无码免费看| 中文成人无码精品久久久不卡| 国产超薄肉色丝袜视频| 中文无码伦av中文字幕在线| 56pao国产成视频永久| 国产精品无码av一区二区三区 | 久久国产精品人妻丝袜| 国产成人国产在线观看| 国产精品va在线观看无码不卡| 中文字幕av一区二区三区人妻少妇| 亚洲日韩av无码一区二区三区人| 国产美女亚洲精品久久久| 国产成人不卡无码免费视频| 亚洲人成在线影院| 欧美丰满大乳大屁股流白浆| 久久久精品久久日韩一区综合| 亚洲欧洲免费三级网站| 在线播放国产麻豆va剧情| 色婷婷综合缴情综免费观看| 熟妇的味道hd中文字幕| 老子午夜精品无码| 国产精品麻豆成人av网| 亚洲人成网77777亚洲色| 国产香蕉97碰碰久久人人| 久久无码专区国产精品s| 中文字幕av伊人av无码av| 免费大片av手机看片不卡| 少妇人妻丰满做爰xxx| 国产精品www夜色视频| 正在播放国产真实哭都没用| 五月丁香六月综合缴情在线| 黑人大荫道bbwbbb高潮潮喷| 中文在线最新版天堂| 免费人成网站在线观看欧美| 亚洲性av网站| 欧美亚洲国产一区二区三区| 日本乱偷互换人妻中文字幕| 日本熟妇人妻videos| 97夜夜澡人人爽人人|