在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC25A46 Antibody, FITC conjugated

  • 中文名稱:
    SLC25A46兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA856895LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC25A46 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC25A46
  • 別名:
    SLC25A46; TB1; Solute carrier family 25 member 46
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Solute carrier family 25 member 46 protein (1-102AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
  • 基因功能參考文獻:
    1. This study reported a novel variant (p.Trp160Ser) in SLC25A46 and we broaden the phenotypic spectrum associated with mutations in SLC25A46. PMID: 28558379
    2. This study identified of a homozygous missense mutation c.1022T>C and a homozygous genomic deletion involving exon 1 in SLC25A46 encoding a mitochondrial protein leading to lethal pontocerebellar hypoplasia with apnoea and profound weakness. PMID: 27543974
    3. These results show that SLC25A46 plays a role in a mitochondrial/endoplasmic reticulum pathway that facilitates lipid transfer, and link altered mitochondrial dynamics to early-onset neurodegenerative disease and cell fate decisions. PMID: 27390132
    4. SLC25A46 is selectively degraded from the outer membrane independently of mitophagy and apoptosis, providing a framework for mechanistic studies in the proteolysis of outer membrane proteins PMID: 28057766
    5. we showed that the Slc25a46 disruption caused a fusion/fission imbalance and an abnormal mitochondrial architecture that disturbed mitochondrial metabolism. These data extended the range of phenotypes associated with Slc25a46 dysfunction. Moreover, this Slc25a46 knock-out mouse model should be useful to further elucidate the role of SLC25A46 in mitochondrial dynamics PMID: 28376083
    6. Our mutant mice provide a valid model for understanding the mechanistic basis of the complex SLC25A46-mediated pathologies, as well as for screening potential therapeutic interventions. PMID: 28376086
    7. The rs10056340 single nucleotide polymorphism was significantly associated with atopic dermatitis. PMID: 26464032
    8. Data indicate four families with recessive mutations in solute carrier family 25 member 46 protein (SLC25A46). PMID: 26168012
    9. Rs17132261 was associated with left ventricular hypertrophy in type 2 diabetic patients. PMID: 23879873

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Neuropathy, hereditary motor and sensory, 6B (HMSN6B)
  • 亞細胞定位:
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family
  • 數據庫鏈接:

    HGNC: 25198

    OMIM: 610826

    KEGG: hsa:91137

    STRING: 9606.ENSP00000348211

    UniGene: Hs.75639



主站蜘蛛池模板: 伊人久久大香线蕉综合5g| 国产成人精品综合在线观看| 大地资源网第二页免费观看| 国产精品vr专区| 思思99re6国产在线播放| 无码午夜福利视频1000集| 狠狠色丁香久久综合婷婷| 国产口爆吞精在线视频2020版| 久久亚洲精品成人av无码网站 | 久章草在线精品视频免费观看| 女学生14毛片视频片二毛 | 亚洲热无码av一区二区东京热av| 人人妻人人爽日日人人| 久久久久99精品成人片试看| 国产97色在线 | 日韩| 2020国产欧洲精品网站| 好爽好湿好硬好大免费视频| 97人妻天天摸天天爽天天| 无码人妻精品一区二区三区66| 护士的小嫩嫩好紧好爽| 护士张开腿被奷日出白浆| 国产初高中生真实在线视频 | 日产精品卡1卡2卡三卡在线| 天码人妻一区二区三区| 国产精品偷窥熟女精品视频| 天天做天天爱夜夜爽| 天天做天天爱夜夜爽毛片| 久久综合九色综合欧洲98| 国产精品亚洲综合色区韩国| 大肉大捧一进一出好爽视频动漫| 国产乱人伦偷精品视频免| 亚洲午夜福利在线视频| 好吊视频一区二区三区| 免费裸体黄网站18禁免费| 成人无码专区免费播放三区| 久久人人爽人人爽人人片av高清| 久久综合久久美利坚合众国| 伊人久久久av老熟妇色| 欧美性猛少妇xxxxx免费| 国产美女牲交视频| 日韩精品av一区二区三区|