在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC25A46 Antibody, Biotin conjugated

  • 中文名稱:
    SLC25A46兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA856895LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SLC25A46 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC25A46
  • 別名:
    SLC25A46; TB1; Solute carrier family 25 member 46
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Solute carrier family 25 member 46 protein (1-102AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
  • 基因功能參考文獻(xiàn):
    1. This study reported a novel variant (p.Trp160Ser) in SLC25A46 and we broaden the phenotypic spectrum associated with mutations in SLC25A46. PMID: 28558379
    2. This study identified of a homozygous missense mutation c.1022T>C and a homozygous genomic deletion involving exon 1 in SLC25A46 encoding a mitochondrial protein leading to lethal pontocerebellar hypoplasia with apnoea and profound weakness. PMID: 27543974
    3. These results show that SLC25A46 plays a role in a mitochondrial/endoplasmic reticulum pathway that facilitates lipid transfer, and link altered mitochondrial dynamics to early-onset neurodegenerative disease and cell fate decisions. PMID: 27390132
    4. SLC25A46 is selectively degraded from the outer membrane independently of mitophagy and apoptosis, providing a framework for mechanistic studies in the proteolysis of outer membrane proteins PMID: 28057766
    5. we showed that the Slc25a46 disruption caused a fusion/fission imbalance and an abnormal mitochondrial architecture that disturbed mitochondrial metabolism. These data extended the range of phenotypes associated with Slc25a46 dysfunction. Moreover, this Slc25a46 knock-out mouse model should be useful to further elucidate the role of SLC25A46 in mitochondrial dynamics PMID: 28376083
    6. Our mutant mice provide a valid model for understanding the mechanistic basis of the complex SLC25A46-mediated pathologies, as well as for screening potential therapeutic interventions. PMID: 28376086
    7. The rs10056340 single nucleotide polymorphism was significantly associated with atopic dermatitis. PMID: 26464032
    8. Data indicate four families with recessive mutations in solute carrier family 25 member 46 protein (SLC25A46). PMID: 26168012
    9. Rs17132261 was associated with left ventricular hypertrophy in type 2 diabetic patients. PMID: 23879873

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Neuropathy, hereditary motor and sensory, 6B (HMSN6B)
  • 亞細(xì)胞定位:
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 25198

    OMIM: 610826

    KEGG: hsa:91137

    STRING: 9606.ENSP00000348211

    UniGene: Hs.75639



主站蜘蛛池模板: 欧美日韩中文国产一区发布| 国产乱子伦精品视频| 一区二区乱子伦在线播放 | 波多野结衣的av一区二区三区 | 亚洲欧美成人一区二区三区| 国产亚洲精品a在线无码| 亚洲精品久久久久中文第一幕 | 国产97色在线 | 免费| 老色鬼永久视频网站| 日韩经典精品无码一区| 多人伦交性欧美| 亚洲欧美成aⅴ人在线观看| 精品少妇人妻av免费久久久 | 人妻中文乱码在线网站| 亚洲精品乱码久久久久久v | 亚洲成a人片在线观看国产| 精品人妻伦一二三区久久| 久久精品亚洲男人的天堂| 亚洲人成小说网站色| 欧美综合天天夜夜久久| www国产成人免费观看视频| 女乱高潮久久久久久爽爽| 国产精品亚洲а∨无码播放不卡| 搡老女人老妇女老熟妇| 国产成人av一区二区三区在线| 欧美成人精精品一区二区| 国产98在线 | 免费| 性欧美丰满熟妇xxxx性| 麻豆av一区二区三区| 国产va在线观看免费| 精品久久久久中文字幕加勒比 | 国产乱码免费卡1卡二卡3| 岛国av无码免费无禁网站麦芽| 日韩免费无码专区精品观看 | 成人美女黄网站色大色费全看| 激情无码人妻又粗又大中国人 | 免费看撕开奶罩揉吮奶头视频 | 久久久国产打桩机| 亚洲 日韩 国产 中文有码| 亚洲精品综合欧美一区二区三区 | 少妇久久久久久久久久|