在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC25A38 Antibody, HRP conjugated

  • 中文名稱:
    SLC25A38兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA846607LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC25A38 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC25A38
  • 別名:
    SLC25A38; Mitochondrial glycine transporter; Mitochondrial glycine transporter GlyC; Solute carrier family 25 member 38
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Mitochondrial glycine transporter protein (1-30AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis.
  • 基因功能參考文獻:
    1. report confirms the considerable variability in manifestations among patients with ALAS2 or SLC25A38 mutations and draws attention to differences in the assessment and the monitoring of iron overload and its complications PMID: 28772256
    2. the biochemical and molecular characterization of yeast Hem25p and human SLC25A38, providing evidence that they are mitochondrial carriers for glycine. In particular, the hem25Delta mutant manifests a defect in the biosynthesis of delta-aminolevulinic acid and displays reduced levels of downstream heme and mitochondrial cytochromes. PMID: 27476175
    3. Appoptosin can interact with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. PMID: 26813789
    4. Given the tolerability of glycine and folate in humans, this study points to a potential novel treatment for SLC25A38 congenital sideroblastic anemia PMID: 26821380
    5. This study findings reveal a novel role for appoptosin in neurological disorders with tau neuropathology, linking caspase-3-mediated tau cleavage to synaptic dysfunction and behavioral/motor defects. PMID: 26335643
    6. Letter/Case Report: novel frameshift mutation in SLC25A38 causing congenital sideroblastic anaemia. PMID: 25512395
    7. Several missense mutations are found in SLC25A38 in a Chinese population with congenital sideroblastic anemia. PMID: 24323989
    8. Our study identifies appoptosin as a crucial player in apoptosis and a novel pro-apoptotic protein involved in neuronal cell death. PMID: 23115192
    9. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    10. Mutations in the SLC25A38 gene cause severe, non-syndromic, microcytic/hypochromic sideroblastic anemia in many populations. PMID: 21393332
    11. Twelve CSA probands had biallelic mutations in SLC25A38 PMID: 19731322

    顯示更多

    收起更多

  • 相關疾病:
    Anemia, sideroblastic, 2, pyridoxine-refractory (SIDBA2)
  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family, SLC25A38 subfamily
  • 組織特異性:
    Preferentially expressed in erythroid cells.
  • 數據庫鏈接:

    HGNC: 26054

    OMIM: 205950

    KEGG: hsa:54977

    STRING: 9606.ENSP00000273158

    UniGene: Hs.369615



主站蜘蛛池模板: 亚洲伦无码中文字幕另类| 中文字幕无线码一区二区| 精品久久久久国产免费| 欧美日激情日韩精品嗯| 国产精成a品人v在线播放| 99精品无人区乱码1区2区3区| 国产av无码专区亚洲版综合| 久久香蕉国产线看观看精品yw| 亚洲熟妇国产熟妇肥婆| 久久亚洲精品国产精品777777| 97人妻免费碰视频碰免| 无码纯肉动漫在线观看| 久久久久无码精品国产| 欧美成人片在线观看| 艳妇乳肉豪妇荡乳av无码福利| 欧美又粗又大又硬又长又爽视频 | 另类亚洲综合区图片区小说| 台湾无码av一区二区三区| 精品日产一卡2卡三卡4卡在线 | 老熟女高潮一区二区三区 | 日本熟妇色xxxxx欧美老妇| 国内精品久久久久久tv| av在线播放无码线| 四虎亚洲精品成人a在线观看| 天堂资源在线官网| 日韩高清国产一区在线| 蜜臀av在线播放| 亚洲成av人在线播放无码| 青乐娱精品视频一国产分类| 激情综合丁香五月| 国产在线 | 中文| 99热国产这里只有精品9| 久久精品亚洲综合专区| 国产女人18毛片水真多| 久久人人爽人人爽人人片ⅴ | 51国产黑色丝袜高跟鞋| 欧洲日韩亚洲无线在码| 成年女人看片永久免费视频| 鲁鲁狠狠狠7777一区二区| 人人妻人人澡人人爽超污| 久久久久国产精品人妻aⅴ牛牛|