在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC25A38 Antibody, Biotin conjugated

  • 中文名稱:
    SLC25A38兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA846607LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC25A38 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC25A38
  • 別名:
    SLC25A38; Mitochondrial glycine transporter; Mitochondrial glycine transporter GlyC; Solute carrier family 25 member 38
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Mitochondrial glycine transporter protein (1-30AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis.
  • 基因功能參考文獻:
    1. report confirms the considerable variability in manifestations among patients with ALAS2 or SLC25A38 mutations and draws attention to differences in the assessment and the monitoring of iron overload and its complications PMID: 28772256
    2. the biochemical and molecular characterization of yeast Hem25p and human SLC25A38, providing evidence that they are mitochondrial carriers for glycine. In particular, the hem25Delta mutant manifests a defect in the biosynthesis of delta-aminolevulinic acid and displays reduced levels of downstream heme and mitochondrial cytochromes. PMID: 27476175
    3. Appoptosin can interact with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. PMID: 26813789
    4. Given the tolerability of glycine and folate in humans, this study points to a potential novel treatment for SLC25A38 congenital sideroblastic anemia PMID: 26821380
    5. This study findings reveal a novel role for appoptosin in neurological disorders with tau neuropathology, linking caspase-3-mediated tau cleavage to synaptic dysfunction and behavioral/motor defects. PMID: 26335643
    6. Letter/Case Report: novel frameshift mutation in SLC25A38 causing congenital sideroblastic anaemia. PMID: 25512395
    7. Several missense mutations are found in SLC25A38 in a Chinese population with congenital sideroblastic anemia. PMID: 24323989
    8. Our study identifies appoptosin as a crucial player in apoptosis and a novel pro-apoptotic protein involved in neuronal cell death. PMID: 23115192
    9. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    10. Mutations in the SLC25A38 gene cause severe, non-syndromic, microcytic/hypochromic sideroblastic anemia in many populations. PMID: 21393332
    11. Twelve CSA probands had biallelic mutations in SLC25A38 PMID: 19731322

    顯示更多

    收起更多

  • 相關疾病:
    Anemia, sideroblastic, 2, pyridoxine-refractory (SIDBA2)
  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family, SLC25A38 subfamily
  • 組織特異性:
    Preferentially expressed in erythroid cells.
  • 數據庫鏈接:

    HGNC: 26054

    OMIM: 205950

    KEGG: hsa:54977

    STRING: 9606.ENSP00000273158

    UniGene: Hs.369615



主站蜘蛛池模板: 国产成人无码aa精品一区| 亚洲桃色天堂网| 亚洲精品无码久久久久av麻豆| 亚洲人成无码网站在线观看| 亚洲五月天综合| 亚洲熟妇无码乱子av电影| 午夜性色福利在线观看视频| 精品无码成人网站久久久久久| 久久国产乱子伦免费精品| 私人毛片免费高清影视院| 3p人妻少妇对白精彩视频| 亚洲国产av无码综合原创国产| 边喂奶边中出的人妻| 免费中文熟妇在线影片| 狠狠亚洲婷婷综合色香五月排名| 老湿机国产福利视频| 日韩人妻无码精品二专区| 亚洲中文字幕无码永久在线不卡| 西西人体www大胆高清视频| 国产高清视频一区三区| 久久国产福利一区二区| 日本无卡码高清免费v| 免费网站观看www在线观看| 精品国产乱码久久久久久影片 | 黑人强辱丰满的人妻熟女| 国产一三四2021不卡| 成人区精品一区二区不卡| 又黄又爽又色的免费网站| 精品人妻va出轨中文字幕| 国产成人亚洲综合无码精品| 精产国品一二三产区蘑菇视频| 久久久久久久精品成人执小说一白| 国产又色又刺激高潮视频 | 国产乱子伦一区二区三区四区五区| 国产九九九九九九九a片| 国产一区二区三区乱码在线观看| 国产av人人夜夜澡人人爽 | 国产极品美女高潮抽搐免费网站| 亚洲人成自拍网站在线观看| 欧美巨大黑人精品videos| 久久久99精品免费观看|