在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC25A20 Antibody

  • 中文名稱:
    SLC25A20兔多克隆抗體
  • 貨號:
    CSB-PA021488GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SLC25A20
  • 別名:
    SLC25A20 antibody; CAC antibody; CACTMitochondrial carnitine/acylcarnitine carrier protein antibody; Carnitine/acylcarnitine translocase antibody; CAC antibody; Solute carrier family 25 member 20 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SLC25A20
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
  • 基因功能參考文獻:
    1. we report the first 2 cases of CACTD identified from the mainland China. Apart from a founder mutation c.199-10T>G, we have identified a novel c.1A>G mutation. Patients with Carnitine-acylcarnitine translocase deficiency with a genotype of c.199-10T>G mutation usually presents with a severe clinical phenotype. Early recognition and appropriate treatment is crucial in this highly lethal disorder. PMID: 29137068
    2. We provide evidence that the downregulation of hsa-miR-124-3p, hsa-miR-129-5p and hsa-miR-378 induced an increase in both expression and activity of CPT1A, CACT and CrAT in malignant prostate cells. PMID: 28671672
    3. The antiport mode of transport, typical of mitochondrial carriers such as CAC, results from coupling of uniport reactions in opposite directions mediated by specific amino acid residues. PMID: 25325845
    4. C.576G>A, c.106-2a>t and c.516T>C are novel CACT gene mutations. PMID: 24088670
    5. CPT2 and CACT are crucial for mitochondrial acylcarnitine formation and export to the extracellular fluids in mitochondrial fatty acid beta-oxidation disorders. PMID: 23322164
    6. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    7. Results show Steroid Receptor Coactivator-3 (SRC-3) plays a central role in long chain fatty acid metabolism by directly regulating carnitine/acyl-carnitine translocase (CACT) gene expression. PMID: 22560224
    8. These results show that FOXA and Sp1 sites in HepG2 cells and only the Sp1 site in HEK293 and SK-N-SH cells have a critical role in the transcriptional regulation of the CAC proximal promoter. PMID: 21130740
    9. A deficiency in CACT was treated with a carnitine diet and administration of medium-chain triglycerides. PMID: 15057979
    10. The clinical, biochemical, & molecular features of 6 CACT-deficient patients from Italy, Spain, & North America who had significant clinical heterogeneity are reported. 5 novel & 3 previously reported mutations were found. PMID: 15365988
    11. The modulation of CACT expression has consequences for CPT 1 activity, while the biologic effects of acetyl-carnitine are not associated with a generic supply of energy compounds but to the anaplerotic property of the molecule. PMID: 15515015
    12. Report the outcome of two siblings with CACT deficiency. PMID: 17508264
    13. Functional analysis of mutations of residues Pro278 and Ala279 in A. nidulans, together with kinetic data in reconstituted liposomes, suggest a predominant structural role for these amino acids. PMID: 18307102
    14. PPARalpha regulates the expression of human SLC25A20 via the peroxisome proliferator responsive element. PMID: 19748481

    顯示更多

    收起更多

  • 相關疾病:
    Carnitine-acylcarnitine translocase deficiency (CACTD)
  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family
  • 數據庫鏈接:

    HGNC: 1421

    OMIM: 212138

    KEGG: hsa:788

    STRING: 9606.ENSP00000326305

    UniGene: Hs.13845



主站蜘蛛池模板: 最新国产aⅴ精品无码| 全部免费毛片在线播放| 中文字幕欧美日韩va免费视频 | 国产亚洲婷婷香蕉久久精品| 蜜臀av在线观看| 国产精品自在线拍国产电影| 伊人亚洲综合影院首页| 极品粉嫩福利午夜在线播放| 亚洲精品中文字幕一区二区三区| 日本边添边摸边做边爱的网站| 久久99国产精一区二区三区| 强制高潮18xxxx按摩| 亚洲嫩模喷白浆在线观看| 国产激情з∠视频一区二区| 国产av麻豆mag剧集| 无码动漫性爽xo视频在线观看| 亚洲成l人在线观看线路| 影音先锋女人av鲁色资源网久久| 柠檬福利精品视频导航| 无码中文字幕人妻在线一区二区三区| 国产乱人伦偷精精品视频| 亚洲va国产va天堂va久久| 在线欧美日韩制服国产| 久久99日韩国产精品久久99| 欧美性受xxxx狂喷水| 亚洲熟妇av日韩熟妇在线| 国产精品亚洲欧美大片在线观看| 成熟老妇女毛茸茸的做性| 国精产品999国精产品官网| 天堂中文在线资源| 亚洲乱色伦图片区小说| 亚洲影院丰满少妇中文字幕无码 | 自拍性旺盛老熟女| 精品无码av无码专区| 欧美亚洲另类丝袜综合网| 亚洲一区av无码专区在线观看| 国产一区二区三区四区五区加勒比| 午夜尤物禁止18点击进入| 高清乱码一区二区三区| 国内精品视频一区二区三区| 欧美一区二区三区激情|