在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC25A20 Antibody

  • 中文名稱:
    SLC25A20兔多克隆抗體
  • 貨號:
    CSB-PA070479
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA070479(SLC25A20 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SLC25A20
  • 別名:
    SLC25A20 antibody; CAC antibody; CACTMitochondrial carnitine/acylcarnitine carrier protein antibody; Carnitine/acylcarnitine translocase antibody; CAC antibody; Solute carrier family 25 member 20 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human SLC25A20
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
  • 基因功能參考文獻:
    1. we report the first 2 cases of CACTD identified from the mainland China. Apart from a founder mutation c.199-10T>G, we have identified a novel c.1A>G mutation. Patients with Carnitine-acylcarnitine translocase deficiency with a genotype of c.199-10T>G mutation usually presents with a severe clinical phenotype. Early recognition and appropriate treatment is crucial in this highly lethal disorder. PMID: 29137068
    2. We provide evidence that the downregulation of hsa-miR-124-3p, hsa-miR-129-5p and hsa-miR-378 induced an increase in both expression and activity of CPT1A, CACT and CrAT in malignant prostate cells. PMID: 28671672
    3. The antiport mode of transport, typical of mitochondrial carriers such as CAC, results from coupling of uniport reactions in opposite directions mediated by specific amino acid residues. PMID: 25325845
    4. C.576G>A, c.106-2a>t and c.516T>C are novel CACT gene mutations. PMID: 24088670
    5. CPT2 and CACT are crucial for mitochondrial acylcarnitine formation and export to the extracellular fluids in mitochondrial fatty acid beta-oxidation disorders. PMID: 23322164
    6. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
    7. Results show Steroid Receptor Coactivator-3 (SRC-3) plays a central role in long chain fatty acid metabolism by directly regulating carnitine/acyl-carnitine translocase (CACT) gene expression. PMID: 22560224
    8. These results show that FOXA and Sp1 sites in HepG2 cells and only the Sp1 site in HEK293 and SK-N-SH cells have a critical role in the transcriptional regulation of the CAC proximal promoter. PMID: 21130740
    9. A deficiency in CACT was treated with a carnitine diet and administration of medium-chain triglycerides. PMID: 15057979
    10. The clinical, biochemical, & molecular features of 6 CACT-deficient patients from Italy, Spain, & North America who had significant clinical heterogeneity are reported. 5 novel & 3 previously reported mutations were found. PMID: 15365988
    11. The modulation of CACT expression has consequences for CPT 1 activity, while the biologic effects of acetyl-carnitine are not associated with a generic supply of energy compounds but to the anaplerotic property of the molecule. PMID: 15515015
    12. Report the outcome of two siblings with CACT deficiency. PMID: 17508264
    13. Functional analysis of mutations of residues Pro278 and Ala279 in A. nidulans, together with kinetic data in reconstituted liposomes, suggest a predominant structural role for these amino acids. PMID: 18307102
    14. PPARalpha regulates the expression of human SLC25A20 via the peroxisome proliferator responsive element. PMID: 19748481

    顯示更多

    收起更多

  • 相關疾病:
    Carnitine-acylcarnitine translocase deficiency (CACTD)
  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family
  • 數據庫鏈接:

    HGNC: 1421

    OMIM: 212138

    KEGG: hsa:788

    STRING: 9606.ENSP00000326305

    UniGene: Hs.13845



主站蜘蛛池模板: 亚洲中文字幕aⅴ无码天堂| av永久天堂一区| 国产精品无码永久免费888| 久久午夜无码鲁丝片直播午夜精品| 蜜臀av999无码精品国产专区| 欧美人与性动交α欧美精品 | 情欲少妇人妻100篇| 亚洲性人人天天夜夜摸| 久久亚洲人成电影网| 国产精品玖玖玖在线| 一本大道东京热无码一区| 女人张开腿让男人桶个爽| 欧美xxxxx高潮喷水麻豆| 成 人 黄 色 大片| 亚洲国产制服丝袜高清在线| 欧美性白人极品1819hd| 大又大粗又爽又黄少妇毛片| 中文字幕av高清片| 国产亚洲精品无码不卡| 综合 欧美 小说 另类 图| 制服丝袜另类专区制服| 特级无码毛片免费视频| 亚洲欧洲日产国码中文字幕| 天天鲁在视频在线观看| 中文字幕亚洲情99在线| 99国产精品白浆在线观看免费 | 少妇人妻互换不带套| 日本高清视频色wwwwww色| 热99re久久精品国产首页免费| 午夜福利视频1692| 国产精品人成视频免费999 | 日本少妇高潮喷水视频| 麻豆国产成人av在线播放| 男人狂躁进女人下面免费视频| 国产偷亚洲偷欧美偷精品| 校园春色~综合网| 国产精品卡1卡2卡3网站| 亚洲色大成网站www久久九九 | 国产人无码a在线西瓜影音| 国产亚洲综合久久系列| 女子spa高潮呻吟抽搐|