在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC16A7 Antibody

SLC16A7 Antibody

  • 中文名稱：
    SLC16A7兔多克隆抗體
  • 貨號：
    CSB-PA138945
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA138945(SLC16A7 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: A549 cells, Primary antibody: CSB-PA138945(SLC16A7 Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SLC16A7
  • 別名：
    MCT 2 antibody; MCT antibody; Monocarboxylate transporter 2 antibody; MonocarboxylateTransporter 2 antibody; MOT2 antibody; MOT2_HUMAN antibody; SLC16A7 antibody; Solute carrier family 16 (monocarboxylate transporter), member 7 antibody; Solute carrier family 16 member 7 antibody; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7 antibody; Solute carrier family 16, member 7 (monocarboxylic acid transporter 2) antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SLC16A7
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.
  • 基因功能參考文獻：
    1. Adipocytes promote malignant growth of breast tumors with MCT2 expression via beta-hydroxybutyrate. PMID: 28281525
    2. SLC16A7 (MCT2) epigenetic regulation results in protein over-expression, affecting signalling and cellular phenotypes in prostate cancer PMID: 26035357
    3. Data suggest that monocarboxylate transporter 2 (MCT2) at peroxisomes is related to an increase in beta-oxidation levels which may be crucial for malignant transformation. PMID: 25639644
    4. This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding solute carrier family 16, member 7. PMID: 25243493
    5. Our findings suggest that SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in NSCLC patients who received surgical treatment once validated in future study. PMID: 25578492
    6. SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in CRC patients who received surgical treatment. PMID: 25492048
    7. MCT2-3' UTR SNP (+2626 G > A) had a strong association with oligoasthenoteratozoospermia. PMID: 24799634
    8. this study provided evidence for the presence of MCT2 in prostate cancer, selectively labeling malignant glands. PMID: 23192371
    9. The monocarboxylate transporter 2 (MCT2) protein was tumor-selectively expressed in human colorectal malignancies and knockdown of MCT2 induces mitochondrial dysfunction, cell-cycle arrest, and senescence. PMID: 22964484
    10. Light microscopic immunohistochemistry revealed significantly less perivascular MCT2 immunoreactivity in the hippocampal formation in medial temporal lobe epilepsy than in non-MTLE patients PMID: 22535546
    11. data suggest that extracellular membrane-bound CAIV, but not cytosolic CAII, augments transport activity of MCT2 in a non-catalytic manner, possibly by facilitating a proton pathway other than His-88 PMID: 21680735
    12. Ocular absorption of monocarboxylic acid drugs may be enhanced by MCT transporter SLC16A7, and the absorption route provided by this transporter may be utilized to improve the bioavailability of topically applied ophthalmic drugs. PMID: 20035863
    13. MCT2 immunoreactivity was noted in astrocytic cell bodies from week 19 and spread subsequently to the astrocyte end-feet in contact with blood vessels of visual cortex. PMID: 14757520
    14. Colorectal neoplasms showed a loss of expression of MCT2 in plasma membranes. PMID: 18188595
    15. These data demonstrate neuronal MCT2 expression in human, but since a portion of it exhibits a distinct synaptic localization, it further supports a putative role for MCT2 in adjustment of energy supply to levels of activity. PMID: 18598673

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
  • 組織特異性：
    Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10928

    OMIM: 603654

    KEGG: hsa:9194

    STRING: 9606.ENSP00000261187

    UniGene: Hs.439643



主站蜘蛛池模板： 欧美拍拍视频免费大全| 无码精品a∨在线观看十八禁| 精品无码国产自产在线观看水浒传| 中国娇小与黑人巨大交| 国产性生交xxxxx免费| 成年午夜精品久久久精品| 青椒国产97在线熟女| 国产九九九九九九九a片| 中文字幕在线日亚州9| 久久午夜夜伦鲁鲁片免费无码影视 | 国产成人无码精品久久久免费 | 极品尤物被啪到呻吟喷水| 亚洲va综合va国产产va中文| 久久高清超碰av热热久久| 久久久亚洲精品一区二区三区浴池 | 国产乱辈通伦影片在线播放亚洲| 亚洲国产精品久久一线不卡| 在线播放无码后入内射少妇| 亚洲欧洲成人a∨在线观看| 亚洲精品嫩草研究院久久| 精品无码一区二区三区在线| 少妇挑战黑人高潮惨叫| 宅宅午夜无码一区二区三区| 夜夜高潮天天爽欧美| 亚洲精品92内射| 国产美女爽到喷出水来视频| 久久99亚洲精品久久69| av高清无码 在线播放| 秋霞av在线露丝片av无码| 精品少妇无码一区二区三批| 22222se男人的天堂| 亚洲色18禁成人网站www| 亚洲精品久久国产精品浴池| 欧美大片aaaaa免费观看| 日本内射精品一区二区视频| 男女性潮高清免费网站| 国产尤物在线视精品在亚洲 | 亚洲va天堂va欧美片a在线| 国产传媒精品1区2区3区| 亚洲亚洲人成综合网络| 成人爱做日本视频免费|