在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC16A7 Antibody

SLC16A7 Antibody

  • 中文名稱：
    SLC16A7兔多克隆抗體
  • 貨號：
    CSB-PA138945
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA138945(SLC16A7 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: A549 cells, Primary antibody: CSB-PA138945(SLC16A7 Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SLC16A7
  • 別名：
    MCT 2 antibody; MCT antibody; Monocarboxylate transporter 2 antibody; MonocarboxylateTransporter 2 antibody; MOT2 antibody; MOT2_HUMAN antibody; SLC16A7 antibody; Solute carrier family 16 (monocarboxylate transporter), member 7 antibody; Solute carrier family 16 member 7 antibody; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7 antibody; Solute carrier family 16, member 7 (monocarboxylic acid transporter 2) antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human SLC16A7
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.
  • 基因功能參考文獻：
    1. Adipocytes promote malignant growth of breast tumors with MCT2 expression via beta-hydroxybutyrate. PMID: 28281525
    2. SLC16A7 (MCT2) epigenetic regulation results in protein over-expression, affecting signalling and cellular phenotypes in prostate cancer PMID: 26035357
    3. Data suggest that monocarboxylate transporter 2 (MCT2) at peroxisomes is related to an increase in beta-oxidation levels which may be crucial for malignant transformation. PMID: 25639644
    4. This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding solute carrier family 16, member 7. PMID: 25243493
    5. Our findings suggest that SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in NSCLC patients who received surgical treatment once validated in future study. PMID: 25578492
    6. SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in CRC patients who received surgical treatment. PMID: 25492048
    7. MCT2-3' UTR SNP (+2626 G > A) had a strong association with oligoasthenoteratozoospermia. PMID: 24799634
    8. this study provided evidence for the presence of MCT2 in prostate cancer, selectively labeling malignant glands. PMID: 23192371
    9. The monocarboxylate transporter 2 (MCT2) protein was tumor-selectively expressed in human colorectal malignancies and knockdown of MCT2 induces mitochondrial dysfunction, cell-cycle arrest, and senescence. PMID: 22964484
    10. Light microscopic immunohistochemistry revealed significantly less perivascular MCT2 immunoreactivity in the hippocampal formation in medial temporal lobe epilepsy than in non-MTLE patients PMID: 22535546
    11. data suggest that extracellular membrane-bound CAIV, but not cytosolic CAII, augments transport activity of MCT2 in a non-catalytic manner, possibly by facilitating a proton pathway other than His-88 PMID: 21680735
    12. Ocular absorption of monocarboxylic acid drugs may be enhanced by MCT transporter SLC16A7, and the absorption route provided by this transporter may be utilized to improve the bioavailability of topically applied ophthalmic drugs. PMID: 20035863
    13. MCT2 immunoreactivity was noted in astrocytic cell bodies from week 19 and spread subsequently to the astrocyte end-feet in contact with blood vessels of visual cortex. PMID: 14757520
    14. Colorectal neoplasms showed a loss of expression of MCT2 in plasma membranes. PMID: 18188595
    15. These data demonstrate neuronal MCT2 expression in human, but since a portion of it exhibits a distinct synaptic localization, it further supports a putative role for MCT2 in adjustment of energy supply to levels of activity. PMID: 18598673

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
  • 組織特異性：
    Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10928

    OMIM: 603654

    KEGG: hsa:9194

    STRING: 9606.ENSP00000261187

    UniGene: Hs.439643



主站蜘蛛池模板： 亚洲乱码中文字幕综合| 欧美xxxx做受视频| 波多野美乳人妻hd电影欧美| 国精品人妻无码一区二区三区喝尿 | 曰本一道本久久88不卡| 丰满熟女高潮毛茸茸欧洲视频| 日韩电影一区二区三区| 日产电影一区二区三区| 久久五月丁香激情综合| yy111111少妇影院无码| 中字幕视频在线永久在线观看免费| 国产精品日韩av在线播放| 免费无人区男男码卡二卡| 潮喷无码正在播放| 亚洲色精品aⅴ一区区三区| 欧美老熟妇喷水| 国产av亚洲精品ai换脸电影| 又黄又爽又色视频| 成品人视频ww入口| 久久久久免费看成人影片| 2021无码天堂在线| 亚洲乱亚洲乱妇50p| 国产真人无码作爱视频免费| 亚洲国产超清无码专区| 男女猛烈激情xx00免费视频| 天天天欲色欲色www免费| 国产蜜芽尤物在线一区| 日本一卡二卡3卡四卡网站精品| 黄网在线观看免费网站| 男人扒开女人双腿猛进视频| 亚洲 欧洲 日韩 综合色天使| 成年女人毛片免费观看97| 亚洲人成电影在线播放| 国产粉嫩嫩00在线正在播放| 久99久热只有精品国产15| 久久99精品久久久久久秒播| 纯肉无遮挡无码日本动漫| 久久不见久久见免费视频观看 | 久久精品女人天堂av| 久久免费视频精品在线| 欧洲av无码放荡人妇网站|