在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SLC16A7 Antibody, HRP conjugated

  • 中文名稱:
    SLC16A7兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA021414LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SLC16A7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SLC16A7
  • 別名:
    MCT 2 antibody; MCT antibody; Monocarboxylate transporter 2 antibody; MonocarboxylateTransporter 2 antibody; MOT2 antibody; MOT2_HUMAN antibody; SLC16A7 antibody; Solute carrier family 16 (monocarboxylate transporter), member 7 antibody; Solute carrier family 16 member 7 antibody; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7 antibody; Solute carrier family 16, member 7 (monocarboxylic acid transporter 2) antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Monocarboxylate transporter 2 protein (197-279AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.
  • 基因功能參考文獻:
    1. Adipocytes promote malignant growth of breast tumors with MCT2 expression via beta-hydroxybutyrate. PMID: 28281525
    2. SLC16A7 (MCT2) epigenetic regulation results in protein over-expression, affecting signalling and cellular phenotypes in prostate cancer PMID: 26035357
    3. Data suggest that monocarboxylate transporter 2 (MCT2) at peroxisomes is related to an increase in beta-oxidation levels which may be crucial for malignant transformation. PMID: 25639644
    4. This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding solute carrier family 16, member 7. PMID: 25243493
    5. Our findings suggest that SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in NSCLC patients who received surgical treatment once validated in future study. PMID: 25578492
    6. SNPs in MCT1 and MCT2 genes may affect clinical outcomes and can be used to predict the response to adjuvant chemotherapy in CRC patients who received surgical treatment. PMID: 25492048
    7. MCT2-3' UTR SNP (+2626 G > A) had a strong association with oligoasthenoteratozoospermia. PMID: 24799634
    8. this study provided evidence for the presence of MCT2 in prostate cancer, selectively labeling malignant glands. PMID: 23192371
    9. The monocarboxylate transporter 2 (MCT2) protein was tumor-selectively expressed in human colorectal malignancies and knockdown of MCT2 induces mitochondrial dysfunction, cell-cycle arrest, and senescence. PMID: 22964484
    10. Light microscopic immunohistochemistry revealed significantly less perivascular MCT2 immunoreactivity in the hippocampal formation in medial temporal lobe epilepsy than in non-MTLE patients PMID: 22535546
    11. data suggest that extracellular membrane-bound CAIV, but not cytosolic CAII, augments transport activity of MCT2 in a non-catalytic manner, possibly by facilitating a proton pathway other than His-88 PMID: 21680735
    12. Ocular absorption of monocarboxylic acid drugs may be enhanced by MCT transporter SLC16A7, and the absorption route provided by this transporter may be utilized to improve the bioavailability of topically applied ophthalmic drugs. PMID: 20035863
    13. MCT2 immunoreactivity was noted in astrocytic cell bodies from week 19 and spread subsequently to the astrocyte end-feet in contact with blood vessels of visual cortex. PMID: 14757520
    14. Colorectal neoplasms showed a loss of expression of MCT2 in plasma membranes. PMID: 18188595
    15. These data demonstrate neuronal MCT2 expression in human, but since a portion of it exhibits a distinct synaptic localization, it further supports a putative role for MCT2 in adjustment of energy supply to levels of activity. PMID: 18598673

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
  • 組織特異性:
    Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed
  • 數據庫鏈接:

    HGNC: 10928

    OMIM: 603654

    KEGG: hsa:9194

    STRING: 9606.ENSP00000261187

    UniGene: Hs.439643



主站蜘蛛池模板: 亚洲色欲色欲www| 伊人久久综合无码成人网| 日本乱偷人妻中文字幕| 国产精品免费观看久久| 国产日韩欧美久久久精品图片| 亚洲国产av无码一区二区三区| 97久久精品人人槡人妻人| 女女互磨互喷水高潮les呻吟| 精品久久久久国产免费| 日韩av毛片无码免费| 97av麻豆蜜桃一区二区| 日韩av无码中文无码不卡电影 | 国产乱人伦精品一区二区在线观看| 蜜桃视频一区二区在线观看| 日韩国产高清一区二区| 国产片av片永久免费观看| 亚洲无人区一区二区三区| 俺也来俺也去俺也射| 2020最新无码福利视频| 国产真实露脸乱子伦| 成年女人毛片免费视频| 亚洲一区二区女搞男| 久久精品国产男包| 精品久久久久香蕉网| 欧美激情第1页| 国产成人亚洲精品无码蜜芽 | 欧美国产日本高清不卡| 乱色熟女综合一区二区三区 | 免费人成网视频在线观看| 好爽好舒服要高潮了视频| 国产精品爽爽v在线观看无码| 2021国产精品一卡2卡三卡4卡| 久久99日韩国产精品久久99| 欧美顶级少妇做爰hd| 久久精品夜色噜噜亚洲a∨| 97se亚洲综合自在线| 夫妻免费无码v看片| 久久久久国产精品人妻| 满春阁精品a∨在线观看| 欧美精品videosbestsex日本| 少妇内射高潮福利炮|