在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SLC14A1 Antibody

SLC14A1 Antibody

  • 中文名稱：
    SLC14A1兔多克隆抗體
  • 貨號：
    CSB-PA258920
  • 規(guī)格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: CSB-PA258920(SLC14A1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SLC14A1
  • 別名：
    blood group Kidd urea transporter antibody; erythrocyte antibody; HsT1341 antibody; HUT11 antibody; JK antibody; Kidd antibody; kidd (JK) blood group urea transporter B1 antibody; RACH1 antibody; Slc14a1 antibody; solute carrier family 14 (urea transporter) member 1 (Kidd blood group) antibody; Solute carrier family 14 member 1 antibody; Urea transporter 1 antibody; Urea transporter antibody; urea transporter B1 antibody; Urea transporter erythrocyte antibody; urea transporter JK glycoprotein antibody; UT B1 antibody; UT1 antibody; UT1_HUMAN antibody; UTE antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human SLC14A1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
  • 基因功能參考文獻：
    1. The urea transporter subtypes, UT-A1 and UT-B1, were expressed in the skin basal cell layer and exocrine sweat glands. The abundance of UT-A1 and UT-B1 in uremic sweat glands was significantly increased in UP, while the expression of AQP5 was decreased. PMID: 29279852
    2. In addition to the well known Polynesian Jknull allele, three Jknull alleles were detected including one novel Jknull allele: JKA (130A, 220G). PMID: 26969102
    3. The Jk(a-b-) phenotype in the Chinese population shows several different molecular mechanisms. A novel missense mutation nt737T>G of JK gene was found as associated with Jk(a-b-) phenotype. PMID: 25807964
    4. Data indicate that urea transporter UT-A1 successfully trafficking to the apical membrane of the epithelial cells is crucial for the regulation of urea transport. PMID: 23698785
    5. Results suggested that polymorphism in TERTC/T and SLC14A1C/T confirmed high risk for BC in North Indian population. PMID: 25218484
    6. Reduction or loss of UT-B expression may be related to the incidence, progression and invasiveness of bladder urothelial carcinoma. PMID: 25445116
    7. Studies indicate that expression of urea transporter UT-B confers high urea permeability to erythrocytes. PMID: 25298342
    8. Studies indicate that acid substitution in the urea transporter Slc14A1 UT-B protein determines the erythrocyte Kidd blood group antigen. PMID: 25298346
    9. UT-B should be considered as a new member of the water channel family. PMID: 24376529
    10. High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles. PMID: 24845979
    11. these data confirm the presence of UT-B protein within the human bladder. PMID: 25209859
    12. Novel polymorphisms in exon 9 of the JSLC14A1 gene in Japanese individuals associated with the Jk(a-b-) phenotype. PMID: 24877238
    13. Thienoquinoline PU-14 is a selective UT inhibitor and has urea-selective diuretic activity. PMID: 23486518
    14. SLC14A1 could be a unique urea transporter in the bladder that has the ability to influence urine concentration and that this mechanism might explain the increased bladder cancer susceptibility associated with rs10775480. PMID: 23754249
    15. Inhibitor and mutagenesis studies and results of molecular dynamics simulations suggest that NH and HO pass through the three monomeric urea channels in UT-B. PMID: 23552862
    16. Four novel JK-null alleles were noted to be associated with the Jk(a-b-) phenotype. PMID: 22738189
    17. the rate of urea conduction in UT-B is increased by hypoosmotic stress, and the site of osmoregulation coincides with the location of the energy barrier PMID: 22733730
    18. Loss of SLC14A1 is associated with lung adenocarcinoma. PMID: 22223368
    19. rs17674580, or other sequence variants of SLC14A1, indirectly modifies urinary bladder cancer risk by affecting urine production. PMID: 21750109
    20. Genetic variation in SLC14A1 could provide new etiological insights into bladder carcinogenesis. PMID: 21824976
    21. A new allele JK*01W has 3 changes (130G>A, 588A>G, Intron 9-46a>g)in addition to 838G. It is associated with weak expression of the Jk-a antigen on erythrocytes. PMID: 21309779
    22. Results illustrate differential protein abundance of functional UT-B protein in different sections of the human colon, strongly correlating to regions that contain the largest populations of intestinal bacteria. PMID: 19926813
    23. gene encodes the Kidd blood group antigens PMID: 12093813
    24. Kidd antigen/UT-B urea transporter is physiologically expressed in the human colon epithelium, where it could participate in the transport of urea across the colon mucosa. PMID: 14985236
    25. high frequency of JK null allele in Taiwanese indigenous groups PMID: 18713105
    26. Three blood group antigens genes, namely CD55, CD151, and SLC14A1, have been subjected to balancing selection, a process, rare outside MHC genes, which maintains variability at a locus. PMID: 18997004

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Urea transporter family
  • 組織特異性：
    Detected in erythrocytes (at protein level). Erythrocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10918

    OMIM: 111000

    KEGG: hsa:6563

    STRING: 9606.ENSP00000390637

    UniGene: Hs.101307



主站蜘蛛池模板： 国产69精品久久久久人妻| 天天摸天天摸天天天天看| 国产无遮挡又黄又爽动态图| 最新国产av无码专区亚洲| 亚洲欧美乱日韩乱国产| 国产农村妇女aaaaa视频| 国产熟妇另类久久久久久| 男女边吃奶边做边爱视频| 亚洲欧美成人一区二区三区| 国产成a人亚洲精v品无码| 中文字幕人妻被公上司喝醉| 无码三级在线看中文字幕完整版| 97久久精品人妻人人搡人人玩| 国精品无码一区二区三区在线蜜臀| 天天澡日日澡狠狠欧美老妇| 野外少妇激情aa 级视频| 欧美成a人片在线观看久| 女人色极品影院| 国产成人剧情av麻豆果冻| 99精品国产福久久久久久| 超清av在线播放不卡无码| 国产精品爆乳奶水无码视频免费 | 日本高清色倩视频在线观看| 午夜福利一区二区三区在线观看| 精品国产美女av久久久久| 国产精品va在线观看h| 肉色超薄丝袜脚交一区二区| 夜夜爽一区二区三区精品| 国产三级韩国三级日产三级| 免费无码又爽又刺激高潮的app| 人妻无码视频一区二区三区| 日本边添边摸边做边爱喷水| 国内精品一区二区三区不卡| 97精品国产97久久久久久免费| 亚洲精品一区中文字幕乱码| 女人高潮抽搐潮喷小视频| 波多野结衣av在线观看| …日韩人妻无码精品一专区| 华人在线亚洲欧美精品| 国产专区免费资源网站| 搡8o老女人老妇人老熟|