在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SIK3 Antibody

SIK3 Antibody

  • 中文名稱：
    SIK3兔多克隆抗體
  • 貨號：
    CSB-PA897531ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA897531ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human thymus tissue using CSB-PA897531ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SIK3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SIK3
  • 別名：
    SIK3 antibody; KIAA0999 antibody; QSK antibody; L19Serine/threonine-protein kinase SIK3 antibody; EC 2.7.11.1 antibody; Salt-inducible kinase 3 antibody; SIK-3 antibody; Serine/threonine-protein kinase QSK antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein kinase SIK3 protein (60-310AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis. Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3. Prevents HDAC4 translocation to the nucleus.
  • 基因功能參考文獻(xiàn)：
    1. role in mediating high salt and IL-17 synergy leading to breast cancer cell proliferation PMID: 28658303
    2. Results found that CpG sites of C1orf106, DMBX1, and SIK3 mediate the genetic risk of psoriasis in Chinese Han population. PMID: 27980695
    3. SIK3 is activated in human osteoarthritic cartilage. PMID: 27009967
    4. Developmental role of Sik3 in hearing and requirement for the maintenance of adult auditory function is reported. PMID: 25060954
    5. SIK3 variants were associated with hypertriglyceridemia in Mexicans. PMID: 24886709
    6. These results establish the importance of SIK3 as a mitotic regulator and underscore the potential of SIK3 as a druggable antimitotic target. PMID: 24743732
    7. cAMP-mediated regulation of SIK3 suggest that SIK3 may mediate some of the effects of this important second messenger in adipocytes PMID: 22588126
    8. Overexpression of SIK3 promotes G1/S cell cycle progression, bestows survival advantages to cancer cells for growth and correlates the clinicopathological conditions of patients with ovarian cancer. PMID: 21399663
    9. Fecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer. PMID: 18266979

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
  • 組織特異性：
    Expressed in chondrocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29165

    OMIM: 614776

    KEGG: hsa:23387

    STRING: 9606.ENSP00000292055

    UniGene: Hs.167451



主站蜘蛛池模板： 亚洲欧美日韩一区在线观看| 国产色在线 | 国产| 蜜桃av亚洲精品一区二区| 国产精品自在拍首页视频| 免费无码一区二区三区a片百度 | 欧美人做人爱a全程免费| 欧美z0zo人禽交欧美人禽交| 久久国内精品自在自线观看| 国产在线视频一区二区三区98 | 久久久久女教师免费一区| 日韩在线永久免费播放| 免费大片av手机看片不卡| 国产情侣一区二区| 学生妹亚洲一区二区| 欧美阿v天堂视频在99线| 亚洲欧洲精品无码av| 岛国av动作片在线观看 | 亚洲成aⅴ人最新无码| 色偷偷偷在线视频播放| 久久国产精久久精产国| 国产在线高清理伦片a| 国产传媒精品1区2区3区| 国产涩涩视频在线观看| 日躁夜躁狠狠躁2001| 55夜色66夜色国产精品视频 | 久在线视视频在线观看| 熟妇人妻中文字幕无码老熟妇| 老湿机69福利区无码| 日本天天黄网站| 日本中文一区二区三区亚洲| 丰满人妻熟妇乱又伦精品软件 | 日本护士╳╳╳hd少妇| 无套内谢少妇毛片aaaa片免费| 东京热人妻丝袜av无码| 欧美牲交a欧美牲交aⅴ一| 女人被黑人躁得好爽视频| 午夜福利视频一区二区手机免费看| 国产精品无码午夜福利| 日韩av高清在线观看| 国产精成a品人v在线播放| 无码人妻精品一二三区免费|