在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SHPRH Antibody

SHPRH Antibody

  • 中文名稱：
    SHPRH兔多克隆抗體
  • 貨號：
    CSB-PA619905LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA619905LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of SH-SY5Y cells with CSB-PA619905LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SHPRH Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SHPRH
  • 別名：
    bA545I5.2 antibody; E3 ubiquitin-protein ligase SHPRH antibody; FLJ27258 antibody; FLJ37625 antibody; FLJ45012 antibody; FLJ90837 antibody; histone-linker antibody; KIAA2023 antibody; MGC134886 antibody; PHD and RING finger domain-containing helicase antibody; Shprh antibody; SHPRH_HUMAN antibody; SNF2 antibody; SNF2 histone linker PHD RING helicase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase SHPRH protein (1362-1512AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，SHPRH Antibody (CSB-PA619905LA01HU)，的標記方式是Non-conjugated。對于SHPRH Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA619905LB01HU SHPRH Antibody, HRP conjugated ELISA
    FITC CSB-PA619905LC01HU SHPRH Antibody, FITC conjugated
    Biotin CSB-PA619905LD01HU SHPRH Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
  • 基因功能參考文獻：
    1. This study suggests that SHPRH could be a link between mTOR-mediated epigenetic regulations and rRNA transcription, while concomitantly affecting genomic integrity. PMID: 29139335
    2. evidence that SHPRH functions in rRNA transcription through its interaction with histone H3 in a mammalian target of rapamycin (mTOR)-dependent manner PMID: 28400511
    3. HLTF and SHPRH suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV rays and methyl methanesulfonate. PMID: 21396873
    4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    5. SHPRH maps to 6q24 and is a possible candidate for the tumor suppressor gene reported from that region. PMID: 12837266
    6. SHPRH function is an important deterrent to mutagenesis and carcinogenesis in humans PMID: 17108083
    7. We report that a putative tumor suppressor gene, SHPRH, is a human orthologue of yeast RAD5.The yRad5/SHPRH-dependent pathway is a conserved and fundamental DNA repair mechanism that protects the genome from genotoxic stress. PMID: 17130289
    8. HLTF and SHPRH are functional homologues of yeast Rad5 that cooperatively mediate PCNA polyubiquitination and maintain genomic stability. PMID: 18719106

    顯示更多

    收起更多

  • 蛋白家族：
    SNF2/RAD54 helicase family
  • 組織特異性：
    Broadly expressed.
  • 數據庫鏈接：

    HGNC: 19336

    OMIM: 608048

    KEGG: hsa:257218

    STRING: 9606.ENSP00000275233

    UniGene: Hs.723297



主站蜘蛛池模板： 男女啪啪抽搐高潮动态图| 久久高清内射无套| 国产亚洲精品欧洲在线视频| 久久66热人妻偷产精品| 国产拍揄自揄精品视频| 综合亚洲另类欧美久久成人精品| 西西人体做爰大胆gogo| 饥渴少妇av无码影片| 亚洲精品久久国产高清小说| 男人用嘴添女人下身免费视频| 无码 人妻 在线 视频| 日韩精品一区二区三区在线观看l| 中文字幕 欧美精品 第1页| 强行无套内谢大学生初次| 亚洲色成人网站www永久四虎| 大桥未久亚洲一区二区| 久久只有这里有精品4| 色婷婷综合久久久久中文| 风流老熟女一区二区三区| 成人影院yy111111在线| 色夜码无码av网站| 男人靠女人免费视频网站| 久久久亚洲欧洲日产国码606| 免费无码又爽又刺激成人 | 久久av无码精品人妻出轨| 久久久性色精品国产免费观看 | 国产97色在线 | 免费| 欧美兽交xxxx×视频| 少妇无码av无码去区钱| 久久无码人妻影院| 人妻少妇久久中文字幕456| 亚洲男人的天堂在线va| 在线观看肉片av网站免费| 国产麻豆9l精品三级站| 国产女人高潮抽搐叫床视频| 夜夜香夜夜摸夜夜添视频| 18禁黄无遮挡网站| 日韩精品无码免费专区网站| 无码熟熟妇丰满人妻porn| 午夜性刺激免费看视频| 亚洲欧洲av无码专区|