在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SHPRH Antibody

SHPRH Antibody

  • 中文名稱：
    SHPRH兔多克隆抗體
  • 貨號：
    CSB-PA059933
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA059933(SHPRH Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    SHPRH
  • 別名：
    bA545I5.2 antibody; E3 ubiquitin-protein ligase SHPRH antibody; FLJ27258 antibody; FLJ37625 antibody; FLJ45012 antibody; FLJ90837 antibody; histone-linker antibody; KIAA2023 antibody; MGC134886 antibody; PHD and RING finger domain-containing helicase antibody; Shprh antibody; SHPRH_HUMAN antibody; SNF2 antibody; SNF2 histone linker PHD RING helicase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human SHPRH
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:30-1:150
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
  • 基因功能參考文獻：
    1. This study suggests that SHPRH could be a link between mTOR-mediated epigenetic regulations and rRNA transcription, while concomitantly affecting genomic integrity. PMID: 29139335
    2. evidence that SHPRH functions in rRNA transcription through its interaction with histone H3 in a mammalian target of rapamycin (mTOR)-dependent manner PMID: 28400511
    3. HLTF and SHPRH suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV rays and methyl methanesulfonate. PMID: 21396873
    4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    5. SHPRH maps to 6q24 and is a possible candidate for the tumor suppressor gene reported from that region. PMID: 12837266
    6. SHPRH function is an important deterrent to mutagenesis and carcinogenesis in humans PMID: 17108083
    7. We report that a putative tumor suppressor gene, SHPRH, is a human orthologue of yeast RAD5.The yRad5/SHPRH-dependent pathway is a conserved and fundamental DNA repair mechanism that protects the genome from genotoxic stress. PMID: 17130289
    8. HLTF and SHPRH are functional homologues of yeast Rad5 that cooperatively mediate PCNA polyubiquitination and maintain genomic stability. PMID: 18719106

    顯示更多

    收起更多

  • 蛋白家族：
    SNF2/RAD54 helicase family
  • 組織特異性：
    Broadly expressed.
  • 數據庫鏈接：

    HGNC: 19336

    OMIM: 608048

    KEGG: hsa:257218

    STRING: 9606.ENSP00000275233

    UniGene: Hs.723297



主站蜘蛛池模板： 最新高清中文字幕免费mv| 少妇扒开粉嫩小泬视频| 日韩无码专区| 久久国产精品萌白酱免费| 亚洲精品午夜一区二区电影院 | 欧美成 人影片 aⅴ免费观看| 一本大道大臿蕉视频无码| 亚洲乱码av中文一区二区| 狠狠躁夜夜躁人人爽超碰97香蕉| 国产亚洲欧美另类一区二区 | 永久免费无码av在线网站| 国产美女遭强高潮网站下载 | 欧美又黄又大又爽a片三年片| 撕开奶罩揉吮奶头视频| 欧美成年视频在线观看| 隔壁老王国产在线精品| 2018天天躁夜夜躁狠狠躁| 最新69成人精品视频免费| 日韩乱码人妻无码中文视频| 国产精品一久久香蕉国产线看观看 | 亚洲最新无码中文字幕久久| 亚洲乱码中文字幕久久孕妇黑人| 男人的天堂av社区在线| 久久久综综合色一本伊人| 亲嘴扒胸摸屁股激烈网站 | 国产真人性做爰久久网站| 无码av免费毛片一区二区| 偷窥国产亚洲免费视频| 国产精品日本亚洲欧美| 色婷婷综合久久久中文字幕| 亚洲精品综合五月久久小说| 女人高潮抽搐潮喷视频开腿| 无码国产成人久久| 亚洲综合色成在线播放| 国产喷水福利在线视频| 扒开双腿猛进入喷水高潮叫声| 亚洲午夜福利精品无码不卡| www插插插无码免费视频网站 | 成 人免费va视频| 久久www免费人成人片| 国产裸体xxxx视频在线播放|