SHPK Antibody

說明書

產品詳情

Uniprot No.：

Q9UHJ6
基因名：

SHPK
別名：

Carbohydrate kinase like antibody; Carbohydrate kinase like protein antibody; Carbohydrate kinase-like protein antibody; CARKL antibody; Sedoheptulokinase antibody; SHK antibody; Shpk antibody; SHPK_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SHPK
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a modulator of macrophage activation through control of glucose metabolism.
基因功能參考文獻：
1. CARKL-dependent metabolic reprogramming is required for proper M1- and M2-like macrophage polarization PMID: 22682222
2. the CARKL-encoded protein, sedoheptulokinase (SHK), is responsible for the reaction: sedoheptulose + ATP --> sedoheptulose-7-phosphate + ADP, and deletion of CARKL causes urinary accumulation of sedoheptulose and erythritol PMID: 18186520
相關疾病：

Sedoheptulokinase deficiency (SHPKD)
亞細胞定位：

Cytoplasm.
蛋白家族：

FGGY kinase family
組織特異性：

Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain.
數據庫鏈接：

HGNC: 1492

OMIM: 605060

KEGG: hsa:23729

STRING: 9606.ENSP00000225519

UniGene: Hs.579217

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