SHPK Antibody

說明書

中文名稱：

SHPK兔多克隆抗體
貨號(hào)：

CSB-PA833951
規(guī)格：

￥2024
圖片：
Western blot analysis of extracts from Jurkat cells, using CARKL antibody.

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using CARKL antibody.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) SHPK Polyclonal antibody
Uniprot No.：

Q9UHJ6
基因名：

SHPK
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from N-terminal of Human CARKL.
免疫原種屬：

Homo sapiens (Human)
克隆類型：

Polyclonal
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:3000
IHC	1:50-1:100

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a modulator of macrophage activation through control of glucose metabolism.
基因功能參考文獻(xiàn)：
1. CARKL-dependent metabolic reprogramming is required for proper M1- and M2-like macrophage polarization PMID: 22682222
2. the CARKL-encoded protein, sedoheptulokinase (SHK), is responsible for the reaction: sedoheptulose + ATP --> sedoheptulose-7-phosphate + ADP, and deletion of CARKL causes urinary accumulation of sedoheptulose and erythritol PMID: 18186520
相關(guān)疾病：

Sedoheptulokinase deficiency (SHPKD)
亞細(xì)胞定位：

Cytoplasm.
蛋白家族：

FGGY kinase family
組織特異性：

Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain.
數(shù)據(jù)庫鏈接：

HGNC: 1492

OMIM: 605060

KEGG: hsa:23729

STRING: 9606.ENSP00000225519

UniGene: Hs.579217

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