在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SEPT7 Antibody

  • 中文名稱:
    SEPT7兔多克隆抗體
  • 貨號:
    CSB-PA021030GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    SEPT7
  • 別名:
    CDC10 antibody; CDC10 protein homolog antibody; CDC3 antibody; Cell division cycle 10 antibody; NBLA02942 antibody; SEPT7 antibody; SEPT7_HUMAN antibody; SEPT7A antibody; Septin 7 antibody; Septin-7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SEPT7
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
  • 基因功能參考文獻:
    1. The present study identified that SEPT7 was a potential target of miR5903p and demonstrated that SEPT7 is associated with mediating the proapoptotic effect of miR5903p in human osteoblast cell line hFOB 1.19. PMID: 29568931
    2. SEPT7 overexpression and knockdown sept7 protein suppress the expression of 78 kDa glucoseregulated protein (GRP78), C/EBPhomologous protein (CHOP), pro-caspase3 and cleaved caspase3 and eIf 2alpha protein. PMID: 29344665
    3. Study discloses both SEPT2 and SEPT7 are essential for breast cancer cell migration and invasion by controlling MEK/ERK MAPKs activation. PMID: 27557506
    4. SUMOylation of human septins is critical for septin filament bundling and cytokinesis. PMID: 29051266
    5. Low SEPT7 expression is associated with glioma cell invasion. PMID: 27006177
    6. The results of this study found that bipolar Neural crest cells progenitors lose their polarity, retracting their processes to round for division, but generate neurons with bipolar morphology by emitting processes from the same locations as the progenitor. PMID: 28817802
    7. Results show that SEPT7 is involved in glioma cell migration with the assistance of cofilin phosphomediated cytoskeleton locomotion. PMID: 26846171
    8. Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis PMID: 25380047
    9. Significantly lower SEPT7 expression in all expressional categories in encapsulated papillary thyroid carcinoma, follicular variant group may be a sign of different molecular signature in this type of tissue. PMID: 24685401
    10. In response to Candida albicans infection, SEPT7 forms a complex with endothelial cell N-cadherin, is required for normal accumulation of N-cadherin around hyphae, and is necessary for maximal fungal endocytosis. PMID: 24345743
    11. Significantly lower SEPT7 expression in encapsulated follicular variant of papillary thyroid carcinoma may be a sign of different molecular signature in this type of tissue. PMID: 24685401
    12. SEPT2 forms a 1:1:1 complex with SEPT7 and SEPT9. PMID: 23572511
    13. miR-30a-5p is a bona fide negative regulator of SEPT7 and the oncogenic activity of miR-30a-5p in human gliomas is at least in part through the repression of SEPT7 PMID: 23383034
    14. Myeloid K562 cells express three SEPT9 isoforms, all of which have an equal propensity to hetero-oligomerize with SEPT7-containing hexamers to generate octameric heteromers. PMID: 22956766
    15. Mutagenic analyses revealed that mutation of a potential phosphorylation site in SEPT7 (Y318) regulates the interaction with other septins. PMID: 21767235
    16. the purification, crystallization and structure for the GTP-binding domain of human septin 7 PMID: 22064074
    17. Sept7 occupies the ends of hexameric building blocks which assemble into non-polarised filaments. PMID: 21824007
    18. The SEPT7 provides the directional guidance cues necessary for polarizing the epithelial microtubule network. PMID: 21788367
    19. Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 group, SEPT3 group and SEPT7 group. PMID: 21082023
    20. SEPT7 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
    21. SEPT7 is involved in the regulation of sperm maturation. PMID: 20352323
    22. The expression of SEPT7 mRNA was significantly decreased by 6.9% in subjects with schizophrenia. PMID: 20385374
    23. This study demonstrates that SEPT7 is involved in gliomagenesis and suppresses glioma cell growth. PMID: 20035367
    24. SEPT7 plays an important role in the glioma cell invasion. PMID: 19916744
    25. regulated but the expression of CDK9, CDC20 and CLK3 was down- regulated in azoospermic testes. PMID: 19426592
    26. Sept7/9b/11 form a complex that has effects on filament elongation, bundling, or disruption PMID: 15485874
    27. septin 2, 6, and 7 complexes make up polymerized filaments PMID: 16914550
    28. crystal structures of the human SEPT2 G domain and the heterotrimeric human SEPT2-SEPT6-SEPT7 complex PMID: 17637674
    29. Demonstrate connection between septins/SOCS7/NCK signaling and the DNA damage response. PMID: 17803907
    30. SEPT7 forms a link between kinetochore distribution of CENP-E and the mitotic spindle checkpoint. PMID: 18460473
    31. SEPT7 gene can inhibit the invasion and migration ability of U251 glioma cells by reversing imbalanced state of MMPs/TIMPs, downregulating expression of integrin alpha(v)beta(3) and altering structure of tubulin-alpha. PMID: 18543212

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
  • 蛋白家族:
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 1717

    OMIM: 603151

    KEGG: hsa:989

    STRING: 9606.ENSP00000381992

    UniGene: Hs.191346



主站蜘蛛池模板: 久久99国产综合精品女同| а√天堂资源官网在线资源| 久久久国产精华液| 最近中文字幕免费mv在线| 欧美视频网站www色| 久久99精品久久只有精品| 国色天香成人网| 久久亚洲国产精品亚洲老地址| 2021在线不卡国产麻豆| 免费人成在线观看视频高潮| 中文字幕乱码人妻二区三区| 国产成人无码va在线观看| 中国xxx农村性视频| 国产超碰人人模人人爽人人添| 无尺码精品产品日韩| 新版天堂资源中文www连接| 亚洲男人a在天堂线一区| 亚洲成av人的天堂在线观看| 久久久久久a亚洲欧洲av| 青青草国产精品欧美成人| 日韩成人av无码一区二区三区| 亚洲色欲色欱www在线| 成人乱人乱一区二区三区| 无码国产成人午夜电影观看| 正在播放国产真实露脸高清| 最新精品香蕉在线| 人人爽天天碰天天躁夜夜躁| 日本妇人成熟免费| 国产成人毛片在线视频软件| 亚欧成人无码av在线播放| 隔壁人妻偷人bd中字| 特黄特级毛片免费视频| 又黄又湿啪啪响18禁| 激情综合一区二区三区| 精品国精品国产自在久国产87| 午夜福利视频极品国产83| 国产专区免费资源网站| 国产精品无码人妻一区二区在线| 最新色国产精品精品视频| 56pao国产成视频永久| 国产亚洲精品精华液|