在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SEPT7 Antibody

  • 中文名稱:
    SEPT7兔多克隆抗體
  • 貨號:
    CSB-PA620952DSR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: Septin-7 antibody at 9μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: Mouse gonad tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 51 kDa
      Observed band size: 51 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA620952DSR1HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SEPT7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SEPT7
  • 別名:
    CDC10 antibody; CDC10 protein homolog antibody; CDC3 antibody; Cell division cycle 10 antibody; NBLA02942 antibody; SEPT7 antibody; SEPT7_HUMAN antibody; SEPT7A antibody; Septin 7 antibody; Septin-7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Septin-7 protein (308-437AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
  • 基因功能參考文獻:
    1. The present study identified that SEPT7 was a potential target of miR5903p and demonstrated that SEPT7 is associated with mediating the proapoptotic effect of miR5903p in human osteoblast cell line hFOB 1.19. PMID: 29568931
    2. SEPT7 overexpression and knockdown sept7 protein suppress the expression of 78 kDa glucoseregulated protein (GRP78), C/EBPhomologous protein (CHOP), pro-caspase3 and cleaved caspase3 and eIf 2alpha protein. PMID: 29344665
    3. Study discloses both SEPT2 and SEPT7 are essential for breast cancer cell migration and invasion by controlling MEK/ERK MAPKs activation. PMID: 27557506
    4. SUMOylation of human septins is critical for septin filament bundling and cytokinesis. PMID: 29051266
    5. Low SEPT7 expression is associated with glioma cell invasion. PMID: 27006177
    6. The results of this study found that bipolar Neural crest cells progenitors lose their polarity, retracting their processes to round for division, but generate neurons with bipolar morphology by emitting processes from the same locations as the progenitor. PMID: 28817802
    7. Results show that SEPT7 is involved in glioma cell migration with the assistance of cofilin phosphomediated cytoskeleton locomotion. PMID: 26846171
    8. Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis PMID: 25380047
    9. Significantly lower SEPT7 expression in all expressional categories in encapsulated papillary thyroid carcinoma, follicular variant group may be a sign of different molecular signature in this type of tissue. PMID: 24685401
    10. In response to Candida albicans infection, SEPT7 forms a complex with endothelial cell N-cadherin, is required for normal accumulation of N-cadherin around hyphae, and is necessary for maximal fungal endocytosis. PMID: 24345743
    11. Significantly lower SEPT7 expression in encapsulated follicular variant of papillary thyroid carcinoma may be a sign of different molecular signature in this type of tissue. PMID: 24685401
    12. SEPT2 forms a 1:1:1 complex with SEPT7 and SEPT9. PMID: 23572511
    13. miR-30a-5p is a bona fide negative regulator of SEPT7 and the oncogenic activity of miR-30a-5p in human gliomas is at least in part through the repression of SEPT7 PMID: 23383034
    14. Myeloid K562 cells express three SEPT9 isoforms, all of which have an equal propensity to hetero-oligomerize with SEPT7-containing hexamers to generate octameric heteromers. PMID: 22956766
    15. Mutagenic analyses revealed that mutation of a potential phosphorylation site in SEPT7 (Y318) regulates the interaction with other septins. PMID: 21767235
    16. the purification, crystallization and structure for the GTP-binding domain of human septin 7 PMID: 22064074
    17. Sept7 occupies the ends of hexameric building blocks which assemble into non-polarised filaments. PMID: 21824007
    18. The SEPT7 provides the directional guidance cues necessary for polarizing the epithelial microtubule network. PMID: 21788367
    19. Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 group, SEPT3 group and SEPT7 group. PMID: 21082023
    20. SEPT7 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
    21. SEPT7 is involved in the regulation of sperm maturation. PMID: 20352323
    22. The expression of SEPT7 mRNA was significantly decreased by 6.9% in subjects with schizophrenia. PMID: 20385374
    23. This study demonstrates that SEPT7 is involved in gliomagenesis and suppresses glioma cell growth. PMID: 20035367
    24. SEPT7 plays an important role in the glioma cell invasion. PMID: 19916744
    25. regulated but the expression of CDK9, CDC20 and CLK3 was down- regulated in azoospermic testes. PMID: 19426592
    26. Sept7/9b/11 form a complex that has effects on filament elongation, bundling, or disruption PMID: 15485874
    27. septin 2, 6, and 7 complexes make up polymerized filaments PMID: 16914550
    28. crystal structures of the human SEPT2 G domain and the heterotrimeric human SEPT2-SEPT6-SEPT7 complex PMID: 17637674
    29. Demonstrate connection between septins/SOCS7/NCK signaling and the DNA damage response. PMID: 17803907
    30. SEPT7 forms a link between kinetochore distribution of CENP-E and the mitotic spindle checkpoint. PMID: 18460473
    31. SEPT7 gene can inhibit the invasion and migration ability of U251 glioma cells by reversing imbalanced state of MMPs/TIMPs, downregulating expression of integrin alpha(v)beta(3) and altering structure of tubulin-alpha. PMID: 18543212

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
  • 蛋白家族:
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 組織特異性:
    Widely expressed.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 1717

    OMIM: 603151

    KEGG: hsa:989

    STRING: 9606.ENSP00000381992

    UniGene: Hs.191346



主站蜘蛛池模板: 欧美熟妇的性裸交| 狠狠色噜噜狠狠狠狠7777米奇| 天天爽夜夜爽人人爽一区二区| 凹凸国产熟女精品视频| 亚洲精品拍拍央视网出文| 午夜dy888国产精品影院| 国产精品av在线| 人人妻人人澡人人爽欧美一区| 伊人久久大香线蕉在观看| 日本少妇寂寞少妇aaa| 亚洲中文字幕无码中文字| 黑人糟蹋人妻hd中文字幕| 国产成人mv视频在线观看| 中文字幕av无码一二三区电影 | 国产成人精品电影在线观看| 女人被狂躁c到高潮视频| 色www永久免费视频首页| 国产成人a无码短视频 | 亚洲精品久久久一区| 精品国产av 无码一区二区三区| 亚洲乱亚洲乱少妇无码| 国产精品亚洲玖玖玖在线观看| 女厕厕露p撒尿八个少妇| 久久久久女教师免费一区| 国内精品美女视频免费直播| 最新国产成人无码久久| 少妇无码太爽了不卡视频在线看| 人人妻人人澡人人爽欧美一区九九 | 男生白内裤自慰gv白袜男同 | 久久躁狠狠躁夜夜av| 亚洲妇女行蜜桃av网网站| 欧美人与动牲交免费观看网| 内射少妇一区27p| 国产精品一国产精品| 国产亚洲精品久久久久久小舞| 欧美激性欧美激情在线| 日韩内射美女人妻一区二区三区| 欧美大屁股xxxx高跟欧美黑人| 无遮无挡爽爽免费视频| 少妇愉情理伦片bd| 国产亚洲精品久久777777|