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SEMA4B Antibody, Biotin conjugated

  • 中文名稱:
    SEMA4B兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA868280LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SEMA4B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SEMA4B
  • 別名:
    SEMA4B antibody; KIAA1745 antibody; SEMAC antibody; UNQ749/PRO1480 antibody; Semaphorin-4B antibody; Semaphorin-C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Semaphorin-4B protein (163-253AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
  • 基因功能參考文獻:
    1. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. PMID: 25746385
    2. Decrease in SEMA4b levels are associated with metastasis of non-small cell lung cancer. PMID: 25095981
    3. showed that HIF-1alpha recognized a hypoxia-responsive element (HRE) of SEMA4B gene, which is required for HIF-1-repressed SEMA4B expression PMID: 24474252
  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Semaphorin family
  • 數據庫鏈接:

    HGNC: 10730

    KEGG: hsa:10509

    STRING: 9606.ENSP00000332204

    UniGene: Hs.474935



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