在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SDHC Antibody

  • 中文名稱:
    SDHC兔多克隆抗體
  • 貨號:
    CSB-PA859106LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA859106LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA859106LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA859106LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SDHC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    SDHC; CYB560; SDH3; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Integral membrane protein CII-3; QPs-1; QPs1; Succinate dehydrogenase complex subunit C; Succinate-ubiquinone oxidoreductase cytochrome B large subunit; CYBL
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Succinate dehydrogenase cytochrome b560 subunit, mitochondrial protein (30-62AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,SDHC Antibody (CSB-PA859106LA01HU),的標記方式是Non-conjugated。對于SDHC Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA859106LB01HU SDHC Antibody, HRP conjugated ELISA
    FITC CSB-PA859106LC01HU SDHC Antibody, FITC conjugated
    Biotin CSB-PA859106LD01HU SDHC Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  • 基因功能參考文獻:
    1. SDHC Promoter hypermethylation is associated with Parasympathetic Paragangliomas. PMID: 29126304
    2. 31% of the paragangliomas in the French Canadian can be explained by the SDHC mutation (c.397C>T, p.[Arg133Ter]). PMID: 27700540
    3. Loss of the SDHC gene is associated with metastatic sympathetic paraganglioma. PMID: 26162468
    4. This report provides evidence that SDHC promoter methylation can cause Paragangliomas due to SDHC inactivation PMID: 26652933
    5. significant association with overall survival were confirmed for SDHC gene, SDHD gene and FH gene ... SDHC gene and FH gene were the primary factors contributing to the different overall survival time of colorectal carcinoma PMID: 26377099
    6. The discovery of SDHC epimutation provides a unifying explanation for the pathogenesis of SDH-deficient gastrointestinal stromal tumors. PMID: 25540324
    7. Variant in rs3935401 in the 3' untranslated region of SDHC is associated with hepatocellular carcinoma. PMID: 25081338
    8. these data suggest epigenetic inactivation of the SDHC gene locus with functional impairment of the SDHC as a plausible alternate mechanism of tumorigenesis in Carney Triad PMID: 24859990
    9. Thoracic paragangliomas are common in patients with SDHC mutations, and imaging of this area should be included in surveillance of mutation carriers. PMID: 24758179
    10. this study reports the first patient affected by malignant paraganglioma and< moreover, it reports two more unrelated patients with the same genotype and very different clinical presentations. PMID: 24423348
    11. No SDHC mutation were found in patients with sporadic paraganglioma. PMID: 22566194
    12. Biallelic inactivation of the SDHC gene may represent a new pathway of pathogenesis of syndromic and nonsyndromic renal cell carcinoma, perhaps of both clear cell and papillary histologies PMID: 22351710
    13. Case Report: present a 32-year-old man with a familial SDHC mutation who manifests synchronous paragangliomas of the carotid body and the thoracic aortopulmonary window. PMID: 21106325
    14. mammalian cells over expressing mutations in SDHC demonstrate low-dose/low-LET radiation sensitization that is mediated by increased levels of O*- and HO. PMID: 21268708
    15. A splice donor site mutation in SDHC is associates with autosomal dominant malignant and catecholamine-producing paraganglioma PMID: 12658451
    16. description of a large deletion in a complex II gene and confirmation of the role of SDHC in familial and sporadic paragangliomas PMID: 15342702
    17. Mutant protein in transgenic mice generates oxidative stress and can contribute to nuclear DNA damage, mutagenesis, and ultimately, tumorigenesis PMID: 15665296
    18. Germline mutations of SDHC play a minor role in sporadic head and neck paraganglioma. PMID: 16405730
    19. familial gastrointestinal stromal tumors may be caused by mutations of the succinate dehydrogenase subunit genes SDHB, SDHC, and SDHD, and abdominal paragangliomas associated with gastrointestinal tumors may be caused uniquely by SDHC mutations PMID: 17804857
    20. Gene deletions of SDHD and SDHC represent a substantial proportion of all mutations, and must be considered in paraganglioma patients shown to be negative for mutations by sequencing. PMID: 19546167

    顯示更多

    收起更多

  • 相關疾病:
    Paragangliomas 3 (PGL3); Paraganglioma and gastric stromal sarcoma (PGGSS)
  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cytochrome b560 family
  • 數據庫鏈接:

    HGNC: 10682

    OMIM: 602413

    KEGG: hsa:6391

    STRING: 9606.ENSP00000356953

    UniGene: Hs.444472



主站蜘蛛池模板: 精品国产精品久久一区免费式| 性色av免费网站| 久久精品99久久香蕉国产色戒| 国产看黄网站又黄又爽又色 | 国精品无码一区二区三区在线蜜臀| 在线亚洲日产一区二区| 国产360激情盗摄全集| 久久精品免费一区二区三区| 久久久亚洲精品成人| 国产农村妇女精品一二区| 欧美肥胖老太vidio在线视频| 日韩人妻不卡一区二区三区| 男人靠女人的免费视频| 精品国产av 无码一区二区三区| 在线观看的网站| 好男人资源在线www免费| 99c视频色欲在线| 浪潮av色综合久久天堂| 免费三级现频在线观看免费| 日韩理论午夜无码| 极品少妇被猛得白浆直喷白浆小说 | 国产手机在线亚洲精品观看| 国产女厕所盗摄老师厕所嘘嘘| а√天堂8资源在线官网| 无套内谢老熟女| 亚洲国产精品久久久久婷婷软件 | 久久亚洲精品成人av无码网站 | 国产精品欧美成人片| 无码午夜福利片| 国产精品va无码一区二区| 成在人av抽搐高潮喷水流白浆| 国产杨幂丝袜av在线播放| 日本另类αv欧美另类aⅴ| 中文字幕无码视频专区| 国产 高潮 抽搐 正在播放 | 亚洲人成人伊人成综合网无码| 国产成人av在线免播放观看| 日韩精品人成在线播放| 欧美又粗又长又爽做受| 日韩内射美女片在线观看网站| 特大黑人娇小亚洲女|