在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SDHC Antibody

  • 中文名稱:
    SDHC兔多克隆抗體
  • 貨號(hào):
    CSB-PA020908GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    SDHC; CYB560; SDH3; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Integral membrane protein CII-3; QPs-1; QPs1; Succinate dehydrogenase complex subunit C; Succinate-ubiquinone oxidoreductase cytochrome B large subunit; CYBL
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SDHC
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  • 基因功能參考文獻(xiàn):
    1. SDHC Promoter hypermethylation is associated with Parasympathetic Paragangliomas. PMID: 29126304
    2. 31% of the paragangliomas in the French Canadian can be explained by the SDHC mutation (c.397C>T, p.[Arg133Ter]). PMID: 27700540
    3. Loss of the SDHC gene is associated with metastatic sympathetic paraganglioma. PMID: 26162468
    4. This report provides evidence that SDHC promoter methylation can cause Paragangliomas due to SDHC inactivation PMID: 26652933
    5. significant association with overall survival were confirmed for SDHC gene, SDHD gene and FH gene ... SDHC gene and FH gene were the primary factors contributing to the different overall survival time of colorectal carcinoma PMID: 26377099
    6. The discovery of SDHC epimutation provides a unifying explanation for the pathogenesis of SDH-deficient gastrointestinal stromal tumors. PMID: 25540324
    7. Variant in rs3935401 in the 3' untranslated region of SDHC is associated with hepatocellular carcinoma. PMID: 25081338
    8. these data suggest epigenetic inactivation of the SDHC gene locus with functional impairment of the SDHC as a plausible alternate mechanism of tumorigenesis in Carney Triad PMID: 24859990
    9. Thoracic paragangliomas are common in patients with SDHC mutations, and imaging of this area should be included in surveillance of mutation carriers. PMID: 24758179
    10. this study reports the first patient affected by malignant paraganglioma and< moreover, it reports two more unrelated patients with the same genotype and very different clinical presentations. PMID: 24423348
    11. No SDHC mutation were found in patients with sporadic paraganglioma. PMID: 22566194
    12. Biallelic inactivation of the SDHC gene may represent a new pathway of pathogenesis of syndromic and nonsyndromic renal cell carcinoma, perhaps of both clear cell and papillary histologies PMID: 22351710
    13. Case Report: present a 32-year-old man with a familial SDHC mutation who manifests synchronous paragangliomas of the carotid body and the thoracic aortopulmonary window. PMID: 21106325
    14. mammalian cells over expressing mutations in SDHC demonstrate low-dose/low-LET radiation sensitization that is mediated by increased levels of O*- and HO. PMID: 21268708
    15. A splice donor site mutation in SDHC is associates with autosomal dominant malignant and catecholamine-producing paraganglioma PMID: 12658451
    16. description of a large deletion in a complex II gene and confirmation of the role of SDHC in familial and sporadic paragangliomas PMID: 15342702
    17. Mutant protein in transgenic mice generates oxidative stress and can contribute to nuclear DNA damage, mutagenesis, and ultimately, tumorigenesis PMID: 15665296
    18. Germline mutations of SDHC play a minor role in sporadic head and neck paraganglioma. PMID: 16405730
    19. familial gastrointestinal stromal tumors may be caused by mutations of the succinate dehydrogenase subunit genes SDHB, SDHC, and SDHD, and abdominal paragangliomas associated with gastrointestinal tumors may be caused uniquely by SDHC mutations PMID: 17804857
    20. Gene deletions of SDHD and SDHC represent a substantial proportion of all mutations, and must be considered in paraganglioma patients shown to be negative for mutations by sequencing. PMID: 19546167

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Paragangliomas 3 (PGL3); Paraganglioma and gastric stromal sarcoma (PGGSS)
  • 亞細(xì)胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cytochrome b560 family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 10682

    OMIM: 602413

    KEGG: hsa:6391

    STRING: 9606.ENSP00000356953

    UniGene: Hs.444472



主站蜘蛛池模板: 一个人看的视频www在线| 少妇激情av一区二区三区| 国产免费人成在线视频app| 中文字幕亚洲综合久久青草| 久久人妻av无码中文专区| 熟女少妇精品一区二区| 欧美精品九九久久久久久久久| 51福利国产在线观看午夜天堂 | 亚洲精品久久7777777| 看国产黄大片在线观看| 欧美日韩一本的免费高清视频| 欧美午夜精品一区二区蜜桃| 一区二区亚洲精品国产精华液| 女人被男人桶30分钟无遮挡动态图 | 欧洲熟妇色xxxxx视频 | 成人国产一区二区三区精品| 免费看成人aa片无码视频吃奶| 美女裸体十八禁免费网站| 国产v综合v亚洲欧| 久久精品日韩av无码| 99久久婷婷国产综合精品青草免费 | 中国少妇内射xxxhd免费| 无码人妻精品一区二区三区99不卡| 国产综合精品久久丫| 制服丝袜亚洲中文欧美在线| 天天摸夜夜添夜夜无码| 在线 | 一区二区三区| 亚洲精品久久yy5099| 成年无码a√片在线观看| 亚洲日韩乱码久久久久久| 日日拍夜夜嗷嗷叫|日日摸| 国产福利一区二区麻豆| 亚洲中文字幕无码一区| 无码精品国产一区二区三区免费| 免费无码又爽又刺激软件下载| 精品久久久无码中文字幕天天| 国产l精品国产亚洲区久久| 波多野结衣乱码中文字幕| 亚洲图片综合图区20p| 少妇熟女高潮流白浆| 国产亚洲产品影视在线产品|