在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SDC3 Antibody

  • 中文名稱:
    SDC3兔多克隆抗體
  • 貨號:
    CSB-PA020890GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    SDC3; KIAA0468; Syndecan-3; SYND3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SDC3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
  • 基因功能參考文獻:
    1. High PTN and N-syndecan expression was closely associated with metastasis and poor prognosis, suggesting that they may promote tumor progression and perineural invasion in the orthotopic mouse model of pancreatic cancer. PMID: 28638231
    2. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells PMID: 25617766
    3. Data indicate that the extracellular and cytoplasmic domains of syndecans 1/2/3/4 are intrinsically disordered regions. PMID: 24956062
    4. frequently expressed in pancreatic cancer and associated with perineural invasion PMID: 24659893
    5. Syndecan-3 expression was not associated with disease progression and outcome in specific subtypes of mammary carcinoma. PMID: 23351331
    6. SDC3 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    7. Syndecan-3 may directly transduce Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) signals or serve as a coreceptor, presenting GFLs to the signaling receptor RET. PMID: 21200028
    8. These findings indicate that SDC3 polymorphisms could contribute to the link between female hyperandrogenism and obesity and suggest a novel potential role for SDC3 as a modulator of gonadal steroid function. PMID: 19820907
    9. Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy. PMID: 11968010
    10. Selective induction of CXCL8 binding site on endothelial syndecan-3 in rheumatoid arthritis(RA) synovium. This site may be involved in leukocyte trafficking into RA synovial tissue. PMID: 16052590
    11. The high expression of syndecan 3 and its localization to the smooth muscle bundles during normal labour, together with the significant reduction in prolonged labour, may indicate a role for this protein in the co-ordination of myometrial contractility. PMID: 16674815
    12. There are ethnic differences in the SDC3 polymorphisms, and the polymorphisms are strongly associated with obesity. PMID: 17018662
    13. Midkine, pleiotrophin (PTN), and their receptors syndecan-3 and receptor protein tyrosine phosphatase beta/zeta, were highly expressed in the striatum during developmen PMID: 17368428
    14. Syndecan-3 was identified as a major HIV-1 attachment receptor on DCs. PMID: 18040049
    15. syndecan TMD homodimerization and heterodimerization can be mediated by GxxxG motifs and modulated by sequence context PMID: 18093920
    16. pleiotrophin (PTN) and syndecan-2 and -3 as direct binding partners of Y-P30. PMID: 18599487
    17. found in 57.9% of pancreatic ductal carcinoma specimens PMID: 18716876
    18. Data report that the bFGF, FGFR1/2 and syndecan 1-4 expressions are altered in bladder tumours. PMID: 19822079

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Syndecan proteoglycan family
  • 組織特異性:
    Expressed in the nervous system, the adrenal gland, and the spleen.
  • 數據庫鏈接:

    HGNC: 10660

    OMIM: 186357

    KEGG: hsa:9672

    STRING: 9606.ENSP00000344468

    UniGene: Hs.158287



主站蜘蛛池模板: 无码办公室丝袜ol中文字幕 | 就去干成人网| 日韩网红少妇无码视频香港| 99久久久无码国产精品秋霞网| 无码专区人妻系列日韩精品| 久久婷婷五月综合色和| 久久66热人妻偷产精品| 久久97超碰色中文字幕总站| 国产男女猛烈无遮挡a片漫画| 另类 专区 欧美 制服| 亚洲午夜无码久久yy6080| 国产 制服丝袜 动漫在线| 日韩欧美在线综合网| 香蕉人妻av久久久久天天| 在线v片免费观看视频| 波多野结衣免费一区视频| 无码人妻av一区二区三区蜜臀 | 色一情一乱一伦| 国产免费看又黄又大又污的胸| 亚洲а∨天堂久久精品| 国产精品偷窥熟女精品视频| 最近免费中文字幕中文高清百度| 乱中年女人伦av二区| av无码天一区二区一三区| 男女性爽大片视频| 风韵犹存丰满大屁股熟妇| 少妇人妻久久无码专区| 国产人妖乱国产精品人妖| 亚洲国产精品久久人人爱| 九色精品国产成人综合网站| 思思99热久久精品在线6| 久久久久久综合网天天| 欧美老妇bbbwwbbbww| 玩50岁四川熟女大白屁股直播| 无码熟妇αⅴ人妻又粗又大| 青娱乐极品视觉盛宴av| 2021最新国产在线人成| 国内精品久久久久影院日本 | 亚洲色欲色欱www在线| 麻豆tv入口在线看| 亚洲va久久久噜噜噜久久无码|