在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SDC3 Antibody

  • 中文名稱:
    SDC3兔多克隆抗體
  • 貨號:
    CSB-PA020890GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    SDC3; KIAA0468; Syndecan-3; SYND3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SDC3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
  • 基因功能參考文獻:
    1. High PTN and N-syndecan expression was closely associated with metastasis and poor prognosis, suggesting that they may promote tumor progression and perineural invasion in the orthotopic mouse model of pancreatic cancer. PMID: 28638231
    2. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells PMID: 25617766
    3. Data indicate that the extracellular and cytoplasmic domains of syndecans 1/2/3/4 are intrinsically disordered regions. PMID: 24956062
    4. frequently expressed in pancreatic cancer and associated with perineural invasion PMID: 24659893
    5. Syndecan-3 expression was not associated with disease progression and outcome in specific subtypes of mammary carcinoma. PMID: 23351331
    6. SDC3 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    7. Syndecan-3 may directly transduce Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) signals or serve as a coreceptor, presenting GFLs to the signaling receptor RET. PMID: 21200028
    8. These findings indicate that SDC3 polymorphisms could contribute to the link between female hyperandrogenism and obesity and suggest a novel potential role for SDC3 as a modulator of gonadal steroid function. PMID: 19820907
    9. Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy. PMID: 11968010
    10. Selective induction of CXCL8 binding site on endothelial syndecan-3 in rheumatoid arthritis(RA) synovium. This site may be involved in leukocyte trafficking into RA synovial tissue. PMID: 16052590
    11. The high expression of syndecan 3 and its localization to the smooth muscle bundles during normal labour, together with the significant reduction in prolonged labour, may indicate a role for this protein in the co-ordination of myometrial contractility. PMID: 16674815
    12. There are ethnic differences in the SDC3 polymorphisms, and the polymorphisms are strongly associated with obesity. PMID: 17018662
    13. Midkine, pleiotrophin (PTN), and their receptors syndecan-3 and receptor protein tyrosine phosphatase beta/zeta, were highly expressed in the striatum during developmen PMID: 17368428
    14. Syndecan-3 was identified as a major HIV-1 attachment receptor on DCs. PMID: 18040049
    15. syndecan TMD homodimerization and heterodimerization can be mediated by GxxxG motifs and modulated by sequence context PMID: 18093920
    16. pleiotrophin (PTN) and syndecan-2 and -3 as direct binding partners of Y-P30. PMID: 18599487
    17. found in 57.9% of pancreatic ductal carcinoma specimens PMID: 18716876
    18. Data report that the bFGF, FGFR1/2 and syndecan 1-4 expressions are altered in bladder tumours. PMID: 19822079

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Syndecan proteoglycan family
  • 組織特異性:
    Expressed in the nervous system, the adrenal gland, and the spleen.
  • 數據庫鏈接:

    HGNC: 10660

    OMIM: 186357

    KEGG: hsa:9672

    STRING: 9606.ENSP00000344468

    UniGene: Hs.158287



主站蜘蛛池模板: 欧美亚洲色aⅴ大片| 国产av天堂无码一区二区三区| 国产97色在线 | 日韩| 中国xxxx做受视频| 国产∨亚洲v天堂无码久久久| 成码无人av片在线电影网站| 日日躁夜夜躁狠狠久久av| 亚洲精品乱码久久久久久不卡| 伊人久久大香线蕉午夜av| 伊人狼人大焦香久久网| 国产乱沈阳女人高潮乱叫老 | 国产av亚洲精品久久久久久小说| 亚洲最大成人网站| 国产精品久久..4399| 国产av无码专区亚洲精品| 国产无遮挡色视频免费观看性色| 国产免费二卡3卡四卡| 真人二十三式性视频(动) | 国产香蕉尹人视频在线| 成人免费的视频| 蜜臀av综合网| 衣服被扒开强摸双乳18禁网站| 女人被狂c躁到高潮视频| 国产一区二区三区四区五区vm| 天干天干夜啦天干天干国产 | 久久不见久久见中文字幕免费| 久热这里只精品99国产6-99re视… | 少妇精品偷拍高潮少妇小说| 国产精品无码午夜免费影院| 99久久精品国产一区二区蜜芽| 少妇高潮喷水在线观看| 伊人久久大香线蕉aⅴ色| 怡红院av亚洲一区二区三区h| 老子午夜精品无码不卡 | 精品夜夜澡人妻无码av| 日本一卡2卡三卡4卡免费网站| 狠狠色噜噜狠狠狠888米奇| 天天弄天天模| 亚洲欧洲av一区二区久久| 亚洲人成人影院在线观看| 亚洲成在人线视av|