在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SDC3 Antibody

SDC3 Antibody

  • 中文名稱：
    SDC3兔多克隆抗體
  • 貨號：
    CSB-PA925237
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA925237(SDC3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA925237(SDC3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA925237(SDC3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    SDC3; KIAA0468; Syndecan-3; SYND3
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human SDC3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
  • 基因功能參考文獻：
    1. High PTN and N-syndecan expression was closely associated with metastasis and poor prognosis, suggesting that they may promote tumor progression and perineural invasion in the orthotopic mouse model of pancreatic cancer. PMID: 28638231
    2. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells PMID: 25617766
    3. Data indicate that the extracellular and cytoplasmic domains of syndecans 1/2/3/4 are intrinsically disordered regions. PMID: 24956062
    4. frequently expressed in pancreatic cancer and associated with perineural invasion PMID: 24659893
    5. Syndecan-3 expression was not associated with disease progression and outcome in specific subtypes of mammary carcinoma. PMID: 23351331
    6. SDC3 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    7. Syndecan-3 may directly transduce Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) signals or serve as a coreceptor, presenting GFLs to the signaling receptor RET. PMID: 21200028
    8. These findings indicate that SDC3 polymorphisms could contribute to the link between female hyperandrogenism and obesity and suggest a novel potential role for SDC3 as a modulator of gonadal steroid function. PMID: 19820907
    9. Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy. PMID: 11968010
    10. Selective induction of CXCL8 binding site on endothelial syndecan-3 in rheumatoid arthritis(RA) synovium. This site may be involved in leukocyte trafficking into RA synovial tissue. PMID: 16052590
    11. The high expression of syndecan 3 and its localization to the smooth muscle bundles during normal labour, together with the significant reduction in prolonged labour, may indicate a role for this protein in the co-ordination of myometrial contractility. PMID: 16674815
    12. There are ethnic differences in the SDC3 polymorphisms, and the polymorphisms are strongly associated with obesity. PMID: 17018662
    13. Midkine, pleiotrophin (PTN), and their receptors syndecan-3 and receptor protein tyrosine phosphatase beta/zeta, were highly expressed in the striatum during developmen PMID: 17368428
    14. Syndecan-3 was identified as a major HIV-1 attachment receptor on DCs. PMID: 18040049
    15. syndecan TMD homodimerization and heterodimerization can be mediated by GxxxG motifs and modulated by sequence context PMID: 18093920
    16. pleiotrophin (PTN) and syndecan-2 and -3 as direct binding partners of Y-P30. PMID: 18599487
    17. found in 57.9% of pancreatic ductal carcinoma specimens PMID: 18716876
    18. Data report that the bFGF, FGFR1/2 and syndecan 1-4 expressions are altered in bladder tumours. PMID: 19822079

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Syndecan proteoglycan family
  • 組織特異性：
    Expressed in the nervous system, the adrenal gland, and the spleen.
  • 數據庫鏈接：

    HGNC: 10660

    OMIM: 186357

    KEGG: hsa:9672

    STRING: 9606.ENSP00000344468

    UniGene: Hs.158287



主站蜘蛛池模板： 少妇伦子伦精品无吗| 久久www成人片免费看| 国产av一二三无码影片| 亚洲人成无码网站| 日本在线观看| 在线天堂资源www在线中文| 亚洲男人的天堂一区二区| 久久久精品免费| 亚洲国产日韩欧美一区二区三区| 色老头av亚洲一区二区男男 | 7777奇米成人狠狠成人影视| 色噜噜狠狠狠狠色综合久一 | 精品国产不卡一区二区三区| 成人欧美一区二区三区a片| 蜜桃少妇av久久久久久久 | 亚洲欧美中文字幕高清在线| 久久久亚洲一区二区三区| 天堂а√在线中文在线新版| 西西444www大胆无码视频| 粗大猛烈进出高潮视频| 香港三日本三级少妇三级66| 性无码免费一区二区三区在线| 亚洲欧洲国产综合aⅴ无码| 国内老熟妇乱子伦视频 | 大黑人交xxxx18视频| 欧美性大战久久久久久| 越猛烈欧美xx00动态图| 亚洲人成77777在线播放网站不卡| 乱人伦中文字幕成人网站在线| 24小时日本在线www免费的| 成人麻豆亚洲综合无码精品| 婷婷射精av这里只有精品| 亚洲精品国产品国语在线| 久久综合九色综合欧美就去吻| 亚洲欧美国产va在线播放| 国产xxx69麻豆国语对白| 国产一区二区野外| 亚洲中文超碰中文字幕| 少妇粉嫩小泬喷水视频www| 免费观看性行为视频的网站| 欧美激烈精交gif动态图|