在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SDC3 Antibody

  • 中文名稱:
    SDC3兔多克隆抗體
  • 貨號:
    CSB-PA925237
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA925237(SDC3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA925237(SDC3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA925237(SDC3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    SDC3; KIAA0468; Syndecan-3; SYND3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human SDC3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
  • 基因功能參考文獻:
    1. High PTN and N-syndecan expression was closely associated with metastasis and poor prognosis, suggesting that they may promote tumor progression and perineural invasion in the orthotopic mouse model of pancreatic cancer. PMID: 28638231
    2. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells PMID: 25617766
    3. Data indicate that the extracellular and cytoplasmic domains of syndecans 1/2/3/4 are intrinsically disordered regions. PMID: 24956062
    4. frequently expressed in pancreatic cancer and associated with perineural invasion PMID: 24659893
    5. Syndecan-3 expression was not associated with disease progression and outcome in specific subtypes of mammary carcinoma. PMID: 23351331
    6. SDC3 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    7. Syndecan-3 may directly transduce Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) signals or serve as a coreceptor, presenting GFLs to the signaling receptor RET. PMID: 21200028
    8. These findings indicate that SDC3 polymorphisms could contribute to the link between female hyperandrogenism and obesity and suggest a novel potential role for SDC3 as a modulator of gonadal steroid function. PMID: 19820907
    9. Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy. PMID: 11968010
    10. Selective induction of CXCL8 binding site on endothelial syndecan-3 in rheumatoid arthritis(RA) synovium. This site may be involved in leukocyte trafficking into RA synovial tissue. PMID: 16052590
    11. The high expression of syndecan 3 and its localization to the smooth muscle bundles during normal labour, together with the significant reduction in prolonged labour, may indicate a role for this protein in the co-ordination of myometrial contractility. PMID: 16674815
    12. There are ethnic differences in the SDC3 polymorphisms, and the polymorphisms are strongly associated with obesity. PMID: 17018662
    13. Midkine, pleiotrophin (PTN), and their receptors syndecan-3 and receptor protein tyrosine phosphatase beta/zeta, were highly expressed in the striatum during developmen PMID: 17368428
    14. Syndecan-3 was identified as a major HIV-1 attachment receptor on DCs. PMID: 18040049
    15. syndecan TMD homodimerization and heterodimerization can be mediated by GxxxG motifs and modulated by sequence context PMID: 18093920
    16. pleiotrophin (PTN) and syndecan-2 and -3 as direct binding partners of Y-P30. PMID: 18599487
    17. found in 57.9% of pancreatic ductal carcinoma specimens PMID: 18716876
    18. Data report that the bFGF, FGFR1/2 and syndecan 1-4 expressions are altered in bladder tumours. PMID: 19822079

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Syndecan proteoglycan family
  • 組織特異性:
    Expressed in the nervous system, the adrenal gland, and the spleen.
  • 數據庫鏈接:

    HGNC: 10660

    OMIM: 186357

    KEGG: hsa:9672

    STRING: 9606.ENSP00000344468

    UniGene: Hs.158287



主站蜘蛛池模板: 人妻无码久久久久久久久久久| 亚洲精品国产美女久久久| 国内精品视频一区二区八戒| 欧洲美女熟乱av| 精品无码国产一区二区三区麻豆| 丰满少妇弄高潮了www| 亚洲视频日本有码中文| 男女裸交无遮挡啪啪激情试看| 日本高清无卡码一区二区 | 亚洲精品乱码久久久久久中文字幕| 久久婷婷五月综合97色| 爱性久久久久久久久| 国产精品成人永久在线| 国产成 人 综合 亚洲网站| 亚洲.日韩.欧美另类| 成人亚洲性情网站www在线观看| 天堂va蜜桃一区二区三区| 中文在线а天堂| 亚洲 欧洲 日韩 综合色天使| 国精一二二产品无人区免费应用| 午夜亚洲www湿好爽| 亚洲精品久久久久久下一站| 真人做人试看60分钟免费视频 | 老司机导航亚洲精品导航| 亚洲国产精品久久久久4婷婷 | 亚洲国产午夜精品理论片在线播放| 亚洲伊人久久大香线蕉| 欧美大片欧美激情性色a∨在线| 777午夜福利理论电影网| 成人欧美一区二区三区1314| 偷偷要色偷偷中文无码| 狠狠色色综合站| 内射人妻少妇无码一本一道| 五月花成人网| 无码欧美黑人xxx一区二区三区| 内谢少妇xxxxx8老少交| 久久精品国产精品国产精品污| 国产97色在线 | 日韩| 亚洲色成人网站永久| 亚洲精品久久av无码麻| 亚洲色欲色欱www在线|