在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SCYL1 Antibody

SCYL1 Antibody

  • 中文名稱：
    SCYL1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA839356DSR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: SCYL1 antibody at 3.15 μg/ml
      Lane 1: 293T whole cell lysate
      Lane 2: Hela whole cell lysate
      Lane 3: 3T3 whole cell lysate
      Lane 4: A549 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 90, 89, 79, 87, 70 kDa
      Observed band size: 90, 110 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SCYL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SCYL1
  • 別名：
    Coated vesicle associated kinase of 90 kDa antibody; Coated vesicle-associated kinase of 90 kDa antibody; CVAK90 antibody; GKLP antibody; HT019 antibody; Likely ortholog of mouse N terminal kinase like protein antibody; MGC78454 antibody; N terminal kinase like antibody; N terminal kinase like protein antibody; N-terminal kinase-like protein antibody; NKTL antibody; NTKL antibody; NTKL_HUMAN antibody; NTKLBP1 antibody; P105 antibody; SCY L1 antibody; SCY1 like 1 antibody; SCY1 like 1 protein 1 antibody; SCY1-like protein 1 antibody; SCYL 1 antibody; Scyl1 antibody; SCYL1BP1 antibody; TAPK antibody; TEIF antibody; Telomerase regulation associated protein antibody; Telomerase regulation-associated protein antibody; Telomerase transcriptional element interacting factor antibody; Telomerase transcriptional element-interacting factor antibody; Teratoma associated tyrosine kinase antibody; Teratoma-associated tyrosine kinase antibody; TRAP antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human N-terminal kinase-like protein (460-740AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum. Involved in the maintenance of the Golgi apparatus morphology. Has no detectable kinase activity in vitro.; Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region.
  • 基因功能參考文獻(xiàn)：
    1. findings indicate that SCYL1 does not contribute to REST turnover and thus do not support a previous study suggesting a role for SCYL1 in mediating REST degradation PMID: 28570664
    2. Disruptive SCYL1 mutations underlie a syndrome characterized by recurrent episodes of liver failure, peripheral neuropathy, cerebellar atrophy, and ataxia. PMID: 26581903
    3. Data identified the large GTPase dynamin2 as an interacting protein of NTKL, which might be responsible for the phenotype alterations caused by NTKL overexpression, such as cytokinesis failure, increased cell motility and abnormal of cell division. PMID: 25575811
    4. Data reveal that Scyl1 is a key organizer of a subset of the COPI machinery. PMID: 24481816
    5. TEIF is a downstream effector in EGF/PI3K/Akt signaling. PMID: 24769208
    6. TEIF as a novel MSP58-interacting protein. PMID: 24361335
    7. suggested that the interaction of SCYL1BP1/Pirh2 could accelerate Pirh2 degradation through an ubiquitin-dependent pathway. SCYL1BP1 may function as an important tumor suppressor gene in HCC development PMID: 22570270
    8. TEIF protein and centrosome amplification is commonly found in colorectal tumors. The expression level of TEIF is related to tumor histological grade and malignant degree. PMID: 19958622
    9. Scyl1 interacts with 58K/formiminotransferase cyclodeaminase (FTCD) and golgin p115, and is required for the maintenance of Golgi morphology PMID: 20209057
    10. Scyl1 participates in the nuclear aminoacylation-dependent tRNA export pathway. PMID: 20505071
    11. SCYL1-BP1 can be ubiquitinated and degraded by Pirh2 but not by MDM2, which suggests that SCYL1-BP1 can be regulated by Pirh2. PMID: 20598683
    12. NTKL is involved in centrosome-related cellular functions PMID: 12036289
    13. Molecular cloning of telomerase transcriptional elements-interacting factor,(TEIF). TEIF may take part in the transcriptional activation of hTERT. PMID: 15504359
    14. TEIF could specifically activate transcription of beta-pol promoter, but not that of DNA polymerase alpha or delta promoter. The responsible sequences for binding of TEIF were revealed PMID: 15963946
    15. TEIF functions as a centrosome regulator. Its participation in DNA damage response, including telomere dysfunction and tumorigenesis. PMID: 19198626

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Spinocerebellar ataxia, autosomal recessive, 21 (SCAR21)
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner.; [Isoform 1]: Cytoplasm. Note=Cytoplasmic throughout the cell cycle.; [Isoform 2]: Cytoplasm. Note=Cytoplasmic throughout the cell cycle.; [Isoform 3]: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic during interphase and centrosomal during mitosis, it localizes to the centrosomes in a microtubule-independent manner.; [Isoform 6]: Nucleus.
  • 蛋白家族：
    Protein kinase superfamily
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 14372

    OMIM: 607982

    KEGG: hsa:57410

    STRING: 9606.ENSP00000270176

    UniGene: Hs.238839



主站蜘蛛池模板： 久久久综合亚洲色一区二区三区| 亚洲日韩中文字幕在线播放| 99精品久久精品一区二区| 中文字幕亚洲乱码熟女在线| 精品麻豆丝袜高跟鞋av| 国产黑色丝袜视频在线观看网红| 无码人妻精品一二三区免费| 国产乱妇乱子视频在播放| 亚洲中文字幕在线第二页| 欧美成人午夜性视频| 欧美不卡视频一区发布| 亚洲人成网网址在线看| 免费看国产曰批40分钟| 小说区 综合区 首页| 久久精品娱乐亚洲领先 | 在线精品亚洲一区二区小说| 视频分类 国内精品| 无码国产精成人午夜视频一区二区 | www亚洲精品少妇裸乳一区二区| 久久久久国精品产熟女久色| 国产成人精品视觉盛宴| 好爽又高潮了毛片免费下载| 久久成人影院精品777| 欧美成人精品福利视频| 97精品尹人久久大香线蕉 | 9l国产精品久久久久尤物| 国产一区丝袜在线播放| 天天天天躁天天爱天天碰| www一区二区www免费| 亚洲αⅴ无码乱码在线观看性色| 国产精品天干天干在线综合| 亚洲精品久久久久午夜福禁果tⅴ| 国产日韩在线时看高清视频 | 群交射精白浆视频| 日本老妇人乱xxy| 欧美日韩一卡2卡三卡4卡 乱码欧美孕交| 久久国产av影片| 国产不卡视频一区二区三区| 自拍区小说区图片区亚洲| 高清乱码一区二区三区| 亚洲国产果冻传媒av在线观看|