在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. S1PR5 Antibody, HRP conjugated

S1PR5 Antibody, HRP conjugated

  • 中文名稱：
    S1PR5兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA867132LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) S1PR5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    S1PR5; EDG8; Sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sphingosine 1-phosphate receptor 5 protein (309-398AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
  • 基因功能參考文獻：
    1. Reduced DNA methylation may underlie the increased expression of the S1PR5 gene in alveolar macrophages and associated defective efferocytosis in COPD. PMID: 27868302
    2. Data indicate that the mitotic kinase Polo-like kinase 1 (PLK1) was an important effector of S1P-S1P5 signaling, and a new function of the SphK1-S1P pathway specifically in the control of mitosis in HeLa cells. PMID: 28351953
    3. TGF-beta2 dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF by TGF-beta in mesangial cells. PMID: 25601519
    4. This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss. PMID: 23551178
    5. Data show that sphingosine kinase SphK1 and sphingosine-1-phosphate (S1P) receptors S1P1, S1P2, S1P3, and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 levels were highest in primary tumors. PMID: 24903384
    6. Edg-5 receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium. PMID: 22715976
    7. The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation. PMID: 22541110
    8. The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized. PMID: 11705398
    9. differences between hS1P(5) and rS1P(5) will be an important point to be considered in the development of selective receptor antagonists. PMID: 12234605
    10. identify and characterize the gene; describe its expression in normal tissues and large granular lymphocyte leukemia monocytes PMID: 12427546
    11. FTY720 induces time-dependent modulation of S1P receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process. PMID: 17918267
    12. The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis. PMID: 19211033
    13. Results suggest that, under serum-starved conditions, sphingosine 1-phosphate (S1P) further upregulates autophagic activity through S1P(5)-dependent pathways in PC-3 cells. PMID: 19474291

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overex
  • 數據庫鏈接：

    HGNC: 14299

    OMIM: 605146

    KEGG: hsa:53637

    STRING: 9606.ENSP00000328472

    UniGene: Hs.501561



主站蜘蛛池模板： 四房播色综合久久婷婷| 国产一区二区三区成人欧美日韩在线观看| 亚洲国产精品无码专区| 国产粉嫩嫩00在线正在播放| 亚洲无人区午夜福利码高清完整版 | 色综合视频一区中文字幕| 欧美不卡视频一区发布| 人妻中出受孕 中文字幕在线| 少妇伦子伦情品无吗| 蜜桃av久久久一区二区三区麻豆| 动漫精品专区一区二区三区| 中国白嫩丰满人妻videos| 黑人巨大精品欧美一区二区| 日本免费人成视频播放| 亚洲欧美日韩在线资源观看| 最新在线精品国自产拍福利| 国语自产少妇精品视频| 亚洲 自拍 另类小说综合图区| 成年午夜精品久久久精品| 国产精品久久久久久av福利| 日日鲁鲁鲁夜夜爽爽狠狠视频97| 国产美女在线精品免费观看| 久久www成人看片免费不卡| 少妇人妻精品无码专区视频| 中文精品久久久久人妻不卡| 老鸭窝视频在线观看| 国产午夜片无码区在线观看爱情网| 欧美另类bbbxxxxx另类| 国产精品水嫩水嫩| 人成午夜大片免费视频77777| 中日韩精品无码一区二区三区| 国产精品 欧美 亚洲 制服 | 免费无码一区二区三区a片百度| 国产成人精品综合久久久久| 久久免费视频精品在线| 亚洲免费观看视频| 特黄大片又粗又大又暴| 青青草无码免费一二三区| 成人无码精品免费视频在线观看| 亚洲精品一区二三区不卡| 久久综合久久美利坚合众国|