在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. S1PR5 Antibody, FITC conjugated

S1PR5 Antibody, FITC conjugated

  • 中文名稱：
    S1PR5兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA867132LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) S1PR5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    S1PR5; EDG8; Sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sphingosine 1-phosphate receptor 5 protein (309-398AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
  • 基因功能參考文獻：
    1. Reduced DNA methylation may underlie the increased expression of the S1PR5 gene in alveolar macrophages and associated defective efferocytosis in COPD. PMID: 27868302
    2. Data indicate that the mitotic kinase Polo-like kinase 1 (PLK1) was an important effector of S1P-S1P5 signaling, and a new function of the SphK1-S1P pathway specifically in the control of mitosis in HeLa cells. PMID: 28351953
    3. TGF-beta2 dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF by TGF-beta in mesangial cells. PMID: 25601519
    4. This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss. PMID: 23551178
    5. Data show that sphingosine kinase SphK1 and sphingosine-1-phosphate (S1P) receptors S1P1, S1P2, S1P3, and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 levels were highest in primary tumors. PMID: 24903384
    6. Edg-5 receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium. PMID: 22715976
    7. The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation. PMID: 22541110
    8. The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized. PMID: 11705398
    9. differences between hS1P(5) and rS1P(5) will be an important point to be considered in the development of selective receptor antagonists. PMID: 12234605
    10. identify and characterize the gene; describe its expression in normal tissues and large granular lymphocyte leukemia monocytes PMID: 12427546
    11. FTY720 induces time-dependent modulation of S1P receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process. PMID: 17918267
    12. The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis. PMID: 19211033
    13. Results suggest that, under serum-starved conditions, sphingosine 1-phosphate (S1P) further upregulates autophagic activity through S1P(5)-dependent pathways in PC-3 cells. PMID: 19474291

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overex
  • 數據庫鏈接：

    HGNC: 14299

    OMIM: 605146

    KEGG: hsa:53637

    STRING: 9606.ENSP00000328472

    UniGene: Hs.501561



主站蜘蛛池模板： 亚洲欧美色一区二区三区| 国产欧美日韩中文久久| 色狠狠av老熟女| 香蕉成人伊视频在线观看| 国语自产拍精品香蕉在线播放| 成人av久久一区二区三区| 国产剧情无码播放在线观看| 少妇人妻偷人激情视频| 日韩人妻一区二区三区免费| 插鸡网站在线播放免费观看| 国产av影片麻豆精品传媒| 久久久久人妻一区精品果冻| 国模吧无码一区二区三区| √天堂资源地址中文在线| 欧美三级欧美成人高清| 97se狠狠狠狠狼鲁亚洲综合色 | 国内精品久久久久久久久齐齐| 18禁美女黄网站色大片免费网站| 亚洲不卡1卡2卡三卡入口| 影音先锋中文字幕人妻| 国产麻豆放荡av剧情演绎| 无修无码h里番在线播放网站| 国产免费人成在线视频app| 国产成人无码av一区二区| 精品国产成人亚洲午夜福利| 精品国产小视频在线观看| 99久久超碰中文字幕伊人| 成熟女人牲交片免费观看视频| 99久久婷婷国产综合精品电影| 99热这里只有精品最新地址获取| 无码8090精品久久一区| 免费天堂无码人妻成人av电影| 男男车车的车车网站w98免费| 国内精品久久久久伊人av| 久久精品熟女亚州av麻豆| 亚洲综合久久无码色噜噜| 亚洲国产成人久久综合区| 四虎影视久久久免费观看| 亚洲中文字幕无码一去台湾| 人体内射精一区二区三区| 免费大黄网站在线观|