在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. S1PR5 Antibody, FITC conjugated

S1PR5 Antibody, FITC conjugated

  • 中文名稱：
    S1PR5兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA867132LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) S1PR5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    S1PR5; EDG8; Sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Sphingosine 1-phosphate receptor 5 protein (309-398AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
  • 基因功能參考文獻：
    1. Reduced DNA methylation may underlie the increased expression of the S1PR5 gene in alveolar macrophages and associated defective efferocytosis in COPD. PMID: 27868302
    2. Data indicate that the mitotic kinase Polo-like kinase 1 (PLK1) was an important effector of S1P-S1P5 signaling, and a new function of the SphK1-S1P pathway specifically in the control of mitosis in HeLa cells. PMID: 28351953
    3. TGF-beta2 dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF by TGF-beta in mesangial cells. PMID: 25601519
    4. This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss. PMID: 23551178
    5. Data show that sphingosine kinase SphK1 and sphingosine-1-phosphate (S1P) receptors S1P1, S1P2, S1P3, and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 levels were highest in primary tumors. PMID: 24903384
    6. Edg-5 receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium. PMID: 22715976
    7. The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation. PMID: 22541110
    8. The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized. PMID: 11705398
    9. differences between hS1P(5) and rS1P(5) will be an important point to be considered in the development of selective receptor antagonists. PMID: 12234605
    10. identify and characterize the gene; describe its expression in normal tissues and large granular lymphocyte leukemia monocytes PMID: 12427546
    11. FTY720 induces time-dependent modulation of S1P receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process. PMID: 17918267
    12. The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis. PMID: 19211033
    13. Results suggest that, under serum-starved conditions, sphingosine 1-phosphate (S1P) further upregulates autophagic activity through S1P(5)-dependent pathways in PC-3 cells. PMID: 19474291

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overex
  • 數據庫鏈接：

    HGNC: 14299

    OMIM: 605146

    KEGG: hsa:53637

    STRING: 9606.ENSP00000328472

    UniGene: Hs.501561



主站蜘蛛池模板： 少妇系列之白嫩人妻| 无码被窝影院午夜看片爽爽jk | 国产精品亚洲第一区在线观看| 99久久精品国产波多野结衣| 东京热久久综合久久88| 久久国产精品福利一区二区三区| 色综合久久88色综合天天| 国精产品999一区二区三区有限| 免费人成网视频在线观看| 高清乱码一区二区三区| 国产精品一区二区久久不卡| 欧美亚洲色综久久精品国产| 欧美z0zo人禽交欧美人禽交| 午夜精品久久久久久久四虎| 春色校园亚洲愉拍自拍| 夜夜高潮天天爽欧美| 国产人妻一区二区三区久| 免费观看激色视频网站| 免费h动漫无码网站| 东京热人妻丝袜av无码| 午夜精品久久久久久毛片| 日本高清www午色夜com| 免费观看四虎精品国产地址| 亚洲国产精品无码久久秋霞| 伊人久久精品无码麻豆一区| 后入到高潮免费观看| 久久久精品中文字幕麻豆发布| 国产高潮抽搐喷水高清| 亚洲.日韩.欧美另类| 乌克兰少妇xxxx做受| 国产另类ts人妖一区二区| 中文无码字幕中文有码字幕| 狠狠色丁香久久婷婷综合_中| 2019日韩中文字幕mv| 国产成人麻豆亚洲综合无码精品| 国产女人高潮视频在线观看| 一本大道在线观看无码一区| 国产精品亚洲a∨天堂| 免费又黄又硬又爽大片| 成人国产三级在线观看| a欧美爰片久久毛片a片|