在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RPS6KB2 Antibody

RPS6KB2 Antibody

  • 中文名稱：
    RPS6KB2兔多克隆抗體
  • 貨號：
    CSB-PA018470
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA018470(RPS6KB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA018470(RPS6KB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    70 kDa ribosomal protein S6 kinase 2 antibody; EC 2.7.11.1 antibody; KS6B2_HUMAN antibody; p70 beta antibody; p70 ribosomal S6 kinase beta antibody; p70 S6 kinase beta antibody; p70 S6K-beta antibody; p70 S6KB antibody; p70 S6Kbeta antibody; p70(S6K) beta antibody; p70-beta antibody; p70-S6K 2 antibody; P70S6K2 antibody; p70S6Kb antibody; Ribosomal protein S6 kinase 70kDa; polypeptide 2 antibody; Ribosomal protein S6 kinase B2 antibody; Ribosomal protein S6 kinase beta 2 antibody; Ribosomal protein S6 kinase beta-2 antibody; Rps6kb2 antibody; S6 kinase related kinase antibody; S6 kinase-related kinase antibody; S6K beta 2 antibody; S6K beta antibody; S6K-beta antibody; S6K-beta-2 antibody; S6K2 antibody; Serine/threonine protein kinase 14 beta antibody; Serine/threonine-protein kinase 14B antibody; SRK antibody; STK14B antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human RPS6KB2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.
  • 基因功能參考文獻：
    1. Overexpression of catalytically-active Akt or knockdown of glycogen synthase kinase-3 (GSK3)-beta, a substrate for Akt, had little effect on Mcl-1 downregulation caused by S6K2 deficiency PMID: 28301598
    2. We propose that the S6K2/TRBP node controls miRNA biogenesis in HDLECs and provides a molecular link between the mTOR pathway and the miRNA biogenesis machinery. PMID: 27407113
    3. discovered that ERBB4 and S6K2 were the direct targets of miR-193a-3p and that PIK3R3 and mTOR were the direct targets of miR-193a-5p in non-small-cell lung cancer PMID: 24469061
    4. Degradation of Tiam1 by casein kinase 1 and the SCFbetaTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling. PMID: 25124033
    5. The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer. PMID: 24131622
    6. The p85 S6K1 promotes H2O2-induced cell death via a rapamycin-insensitive mechanism. PMID: 22955948
    7. S6K2 amplification was frequently observed in gastric cancer and was related to a poor prognosis PMID: 23393338
    8. Study shows that the two homologues of S6K have distinct effects on Akt activation and cell survivalin breast cancer. PMID: 21427355
    9. heterogeneous ribonucleoprotein F is involved in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway PMID: 20308064
    10. p70 S6 kinase regulates neutrophilic differentiation in HL-60 cells PMID: 12176053
    11. regulation of nucleocytoplasmic shuttling of S6KbetaII by protein kinase C-mediated phosphorylation PMID: 12529391
    12. the PI3K/p70 S6K/c-Myc cascade plays an important role in neutrophilic proliferation in HL-60 cells. PMID: 12818373
    13. These data suggest that activated p70 S6 kinase could mediate an up-regulation of tau translation. PMID: 12875979
    14. p70 ribosomal protein S6 kinase activity was induced by K-Ras in a phosphatidylinositol 3-kinase and mTOR-dependent manner. PMID: 14729629
    15. S6K2 is active throughout the cell cycle with higher activity in G2 and M phases. PMID: 17786541

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily
  • 數據庫鏈接：

    HGNC: 10437

    OMIM: 608939

    KEGG: hsa:6199

    STRING: 9606.ENSP00000308413

    UniGene: Hs.534345



主站蜘蛛池模板： 精品av无码国产一区二区| 护士的小嫩嫩好紧好爽| 婷婷六月丁香缴 清| 国产精品99久久精品| 香蕉噜噜噜噜私人影院| 乱子伦农村xxxxbbb| av制服丝袜白丝国产网站 | 久久久久久久久免费看无码| 精品国产一区二区av麻豆不卡| 他用舌头给我高潮喷水在线 | 亚洲中文在线精品国产| 老熟女高潮喷水了| 女人大荫蒂毛茸茸视频| 内射人妻无套中出无码| 正在播放的国产a一片| 亚洲国产精品一区二区手机| 久久天天躁狠狠躁夜夜爽| 五月天激情国产综合婷婷婷| 国产综合在线观看| 国产免费一卡二卡三卡四卡| 天天爽天天狠久久久综合麻豆| 国产小屁孩cao大人免费| 无套内谢孕妇毛片免费看| аⅴ天堂中文在线网官网| 人人做人人爽国产视| 亚洲国产成人精品激情姿源| 日本三级香港三级三级人!妇久| 亚洲精品久久久中文字幕痴女| 男人添女人下部高潮视频| 亚洲日本中文字幕乱码在线| 国产成人高清精品亚洲| 欧美牲交a欧美牲交aⅴ一| 人妻夜夜爽天天爽| 欧美人与动人物牲交免费观看| 久久精品人人做人人爱爱漫画 | 337p日本欧洲亚洲大胆色噜噜| 亚洲欧美精品综合在线观看| 亚洲中国最大av网站| 性欧美丰满熟妇xxxx性仙踪林 | 亚洲色自偷自拍另类小说| 国产成人av在线播放影院|